Science 3 January 1992: Vol. 255. no. 5040, pp. 79 - 82 DOI: 10.1126/science.1532456

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Articles

The {alpha}{beta} T Cell Receptor Is an Anisotropic Mechanosensor.

S. T. Kim, K. Takeuchi, Z.-Y. J. Sun, M. Touma, C. E. Castro, A. Fahmy, M. J. Lang, G. Wagner, and E. L. Reinherz (2009)
J. Biol. Chem. 284, 31028-31037
 |  Abstract »  |  Full Text »  |  PDF »

The Membrane-proximal Portion of CD3 {epsilon} Associates with the Serine/Threonine Kinase GRK2.

L. M. DeFord-Watts, J. A. Young, L. A. Pitcher, and N. S. C. van Oers (2007)
J. Biol. Chem. 282, 16126-16134
 |  Abstract »  |  Full Text »  |  PDF »

TCR{zeta}dimlymphocytes define populations of circulating effector cells that migrate to inflamed tissues.

Z. Zhang, C. L. Gorman, A.-C. Vermi, C. Monaco, A. Foey, S. Owen, P. Amjadi, A. Vallance, C. McClinton, F. Marelli-Berg, et al. (2007)
Blood 109, 4328-4335
 |  Abstract »  |  Full Text »  |  PDF »

Importance of the CD3{gamma} Ectodomain Terminal beta-Strand and Membrane Proximal Stalk in Thymic Development and Receptor Assembly.

M. Touma, Z.-Y. J. Sun, L. K. Clayton, W. E. Marissen, A. M. Kruisbeek, G. Wagner, and E. L. Reinherz (2007)
J. Immunol. 178, 3668-3679
 |  Abstract »  |  Full Text »  |  PDF »

Non-T Cell Activation Linker (NTAL) Negatively Regulates TREM-1/DAP12-Induced Inflammatory Cytokine Production in Myeloid Cells.

A. S. Tessarz, S. Weiler, K. Zanzinger, P. Angelisova, V. Horejsi, and A. Cerwenka (2007)
J. Immunol. 178, 1991-1999
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Cloning, expression and functional characterization of the putative regeneration and tolerance factor (RTF/TJ6) as a functional vacuolar ATPase proton pump regulatory subunit with a conserved sequence of immunoreceptor tyrosine-based activation motif.

Y. Babichev, A. Tamir, M. Park, S. Muallem, and N. Isakov (2005)
Int. Immunol. 17, 1303-1313
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Solution structure of the CD3{epsilon}{delta} ectodomain and comparison with CD3{epsilon}{gamma} as a basis for modeling T cell receptor topology and signaling.

Z.-Y. J. Sun, S. T. Kim, I. C. Kim, A. Fahmy, E. L. Reinherz, and G. Wagner (2004)
PNAS 101, 16867-16872
 |  Abstract »  |  Full Text »  |  PDF »

Crystal structure of a human CD3-{epsilon}/{delta} dimer in complex with a UCHT1 single-chain antibody fragment.

K. L. Arnett, S. C. Harrison, and D. C. Wiley (2004)
PNAS 101, 16268-16273
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Dissection of the FcR{beta} Signaling Amplifier.

M. On, J. M. Billingsley, M.-H. Jouvin, and J.-P. Kinet (2004)
J. Biol. Chem. 279, 45782-45790
 |  Abstract »  |  Full Text »  |  PDF »

The Three-dimensional Structure of the ZAP-70 Kinase Domain in Complex with Staurosporine: IMPLICATIONS FOR THE DESIGN OF SELECTIVE INHIBITORS.

L. Jin, S. Pluskey, E. C. Petrella, S. M. Cantin, J. C. Gorga, M. J. Rynkiewicz, P. Pandey, J. E. Strickler, R. E. Babine, D. T. Weaver, et al. (2004)
J. Biol. Chem. 279, 42818-42825
 |  Abstract »  |  Full Text »  |  PDF »

NFAM1, an immunoreceptor tyrosine-based activation motif-bearing molecule that regulates B cell development and signaling.

M. Ohtsuka, H. Arase, A. Takeuchi, S. Yamasaki, R. Shiina, T. Suenaga, D. Sakurai, T. Yokosuka, N. Arase, M. Iwashima, et al. (2004)
PNAS 101, 8126-8131
 |  Abstract »  |  Full Text »  |  PDF »

TCR subunit specificity of CTLA-4-mediated signaling.

E. Siu, B. M. Carreno, and J. Madrenas (2003)
J. Leukoc. Biol. 74, 1102-1107
 |  Abstract »  |  Full Text »

Rosmarinic acid inhibits Ca2+-dependent pathways of T-cell antigen receptor-mediated signaling by inhibiting the PLC-gamma 1 and Itk activity.

M.-A. Kang, S.-Y. Yun, and J. Won (2003)
Blood 101, 3534-3542
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Three NFAT Binding Motifs in the 5'-Upstream Region of the Human CD3gamma Gene That Differentially Bind NFATc1, NFATc2, and NF-kappa B p50.

B. M. Badran, S. M. Wolinsky, A. Burny, and K. E. Willard-Gallo (2002)
J. Biol. Chem. 277, 47136-47148
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of CD3{gamma} to TCR regulation and signaling in human mature T lymphocytes.

P. S. Torres, D. A. Zapata, A. Pacheco-Castro, J. L. Rodriguez-Fernandez, C. Cabanas, and J. R. Regueiro (2002)
Int. Immunol. 14, 1357-1367
 |  Abstract »  |  Full Text »  |  PDF »

Contributions of the T Cell Receptor-associated CD3{gamma}-ITAM to Thymocyte Selection.

M. C. Haks, E. Pepin, J. H.N. van den Brakel, S. A.A. Smeele, S. M. Belkowski, H. W.H.G. Kessels, P. Krimpenfort, and A. M. Kruisbeek (2002)
J. Exp. Med. 196, 1-13
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of the TCR C{beta} FG Loop in Thymic Selection and T Cell Function.

T. Sasada, M. Touma, H.-C. Chang, L. K. Clayton, J.-h. Wang, and E. L. Reinherz (2002)
J. Exp. Med. 195, 1419-1431
 |  Abstract »  |  Full Text »  |  PDF »

Interference with Immunoglobulin (Ig){alpha} Immunoreceptor Tyrosine-Based Activation Motif (Itam) Phosphorylation Modulates or Blocks B Cell Development, Depending on the Availability of an Ig{beta} Cytoplasmic Tail.

M. Kraus, L. I. Pao, A. Reichlin, Y. Hu, B. Canono, J. C. Cambier, M. C. Nussenzweig, and K. Rajewsky (2001)
J. Exp. Med. 194, 455-470
 |  Abstract »  |  Full Text »  |  PDF »

The Transmembrane Adaptor Protein Trim Regulates T Cell Receptor (Tcr) Expression and Tcr-Mediated Signaling via an Association with the Tcr {zeta} Chain.

H. Kirchgessner, J. Dietrich, J. Scherer, P. Isomaki, V. Korinek, I. Hilgert, E. Bruyns, A. Leo, A. P. Cope, and B. Schraven (2001)
J. Exp. Med. 193, 1269-1284
 |  Abstract »  |  Full Text »  |  PDF »

Prolonged Exposure of T Cells to TNF Down-Regulates TCR{{zeta}} and Expression of the TCR/CD3 Complex at the Cell Surface.

P. Isomaki, M. Panesar, A. Annenkov, J. M. Clark, B. M. J. Foxwell, Y. Chernajovsky, and A. P. Cope (2001)
J. Immunol. 166, 5495-5507
 |  Abstract »  |  Full Text »  |  PDF »

A Redundant Role of the CD3{{gamma}}-Immunoreceptor Tyrosine-Based Activation Motif in Mature T Cell Function.

M. C. Haks, T. A. Cordaro, J. H. N. van den Brakel, J. B. A. G. Haanen, E. F. R. de Vries, J. Borst, P. Krimpenfort, and A. M. Kruisbeek (2001)
J. Immunol. 166, 2576-2588
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Conserved transmembrane tyrosine residues of the TCR {beta} chain are required for TCR expression and function in primary T cells and hybridomas.

S. Kunjibettu, S. Fuller-Espie, G. B. Carey, and L. M. Spain (2001)
Int. Immunol. 13, 211-222
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Chronic PMA treatment of Jurkat T lymphocytes results in decreased protein tyrosine phosphorylation and inhibition of CD3- but not Ti-dependent antibody-triggered Ca2+ signaling.

C. E. Ahnadi, P. Giguère, S. Gravel, D. Gagné, A.-C. Goulet, T. Fülöp Jr, M. D. Payet, and G. Dupuis (2000)
J. Leukoc. Biol. 68, 293-300
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RasGRP links T-cell receptor signaling to Ras.

J. O. Ebinu, S. L. Stang, C. Teixeira, D. A. Bottorff, J. Hooton, P. M. Blumberg, M. Barry, R. C. Bleakley, H. L. Ostergaard, and J. C. Stone (2000)
Blood 95, 3199-3203
 |  Abstract »  |  Full Text »  |  PDF »

Partially Phosphorylated T Cell Receptor {zeta} Molecules Can Inhibit T Cell Activation.

E. N. Kersh, G. J. Kersh, and P. M. Allen (1999)
J. Exp. Med. 190, 1627-1636
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Bypassing Immunization: Optimized Design of ""Designer T Cells"" against Carcinoembryonic Antigen (CEA)-expressing Tumors, and Lack of Suppression by Soluble CEA.

K. F. Nolan, C.-O. Yun, Y. Akamatsu, J. C. Murphy, S.-O. Leung, E. J. Beecham, and R. P. Junghans (1999)
Clin. Cancer Res. 5, 3928-3941
 |  Abstract »  |  Full Text »  |  PDF »

Identification and Functional Characterization of the {zeta}-Chain Dimerization Motif for TCR Surface Expression.

L. Bolliger and B. Johansson (1999)
J. Immunol. 163, 3867-3876
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Signal Thresholds for the Unique Antigen Receptor-Linked Gene Expression Programs in Mature and Immature B Cells.

R. J. Benschop, D. Melamed, D. Nemazee, and J. C. Cambier (1999)
J. Exp. Med. 190, 749-756
 |  Abstract »  |  Full Text »  |  PDF »

Signals Transduced by CD3{epsilon}, But Not by Surface Pre-TCR Complexes, Are Able to Induce Maturation of an Early Thymic Lymphoma In Vitro.

M. Carleton, N. R. Ruetsch, M. A. Berger, M. Rhodes, S. Kaptik, and D. L. Wiest (1999)
J. Immunol. 163, 2576-2585
 |  Abstract »  |  Full Text »  |  PDF »

The CD3-gamma delta epsilon Transducing Module Mediates CD38-induced Protein-tyrosine Kinase and Mitogen-activated Protein Kinase Activation in Jurkat T Cells.

M. Zubiaur, M. Guirado, C. Terhorst, F. Malavasi, and J. Sancho (1999)
J. Biol. Chem. 274, 20633-20642
 |  Abstract »  |  Full Text »  |  PDF »

CAST, a Novel CD3epsilon -binding Protein Transducing Activation Signal for Interleukin-2 Production in T Cells.

T. Yamazaki, Y. Hamano, H. Tashiro, K. Itoh, H. Nakano, S. Miyatake, and T. Saito (1999)
J. Biol. Chem. 274, 18173-18180
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor {beta} Chain Lacking the Large Solvent-exposed C{beta} FG Loop Supports Normal {alpha}/{beta} T Cell Development and Function in Transgenic Mice.

S. Degermann, G. Sollami, and K. Karjalainen (1999)
J. Exp. Med. 189, 1679-1684
 |  Abstract »  |  Full Text »  |  PDF »

The TCR {zeta}-Chain Immunoreceptor Tyrosine-Based Activation Motifs Are Sufficient for the Activation and Differentiation of Primary T Lymphocytes.

T. L. Geiger, D. Leitenberg, and R. A. Flavell (1999)
J. Immunol. 162, 5931-5939
 |  Abstract »  |  Full Text »  |  PDF »

Generation of antigen-specific cytotoxic T lymphocytes and regulation of cytokine production takes place in the absence of CD3{zeta}.

J. She, M. C. Ruzek, P. Velupillai, I. de Aos, B. Wang, D. A. Harn, J. Sancho, C. A. Biron, and C. Terhorst (1999)
Int. Immunol. 11, 845-857
 |  Abstract »  |  Full Text »  |  PDF »

Surface Expression and Functional Competence of CD3-Independent TCR {zeta}-Chains in Immature Thymocytes.

F. Grassi, E. Barbier, S. Porcellini, H. von Boehmer, and P.-A. Cazenave (1999)
J. Immunol. 162, 2589-2596
 |  Abstract »  |  Full Text »  |  PDF »

The Lck SH3 Domain Is Required for Activation of the Mitogen-activated Protein Kinase Pathway but Not the Initiation of T-cell Antigen Receptor Signaling.

M. F. Denny, H. C. Kaufman, A. C. Chan, and D. B. Straus (1999)
J. Biol. Chem. 274, 5146-5152
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Basis of T Cell Inactivation by CTLA-4.

K. Lee, E. Chuang, M. Griffin, R. Khattri, D. K. Hong, W. Zhang, D. Straus, L. E. Samelson, C. B. Thompson, and J. A. Bluestone (1998)
Science 282, 2263-2266
 |  Abstract »  |  Full Text »

TCR{alpha}{beta} Chains Associate with the Plasma Membrane Independently of CD3 and TCR{zeta} Chains in Murine Primary T Cells.

J. Zhang, K. Salojin, J.-X. Gao, M. Cameron, C. Geisler, and T. L. Delovitch (1998)
J. Immunol. 161, 2930-2937
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Receptor (TCR) Interacting Molecule (TRIM), A Novel Disulfide-linked Dimer Associated with the TCR-CD3-{zeta} Complex, Recruits Intracellular Signaling Proteins to the Plasma Membrane.

E. Bruyns, A. Marie-Cardine, H. Kirchgessner, K. Sagolla, A. Shevchenko, M. Mann, F. Autschbach, A. Bensussan, S. Meuer, and B. Schraven (1998)
J. Exp. Med. 188, 561-575
 |  Abstract »  |  Full Text »  |  PDF »

Fidelity of T Cell Activation Through Multistep T Cell Receptor {zeta}?Phosphorylation.

E. N. Kersh, A. S. Shaw, and P. M. Allen (1998)
Science 281, 572-575
 |  Abstract »  |  Full Text »  |  PDF »

T Cell Activation Induced by Novel Gain-of-function Mutants of Syk and ZAP-70.

L. Zeitlmann, T. Knorr, M. Knoll, C. Romeo, P. Sirim, and W. Kolanus (1998)
J. Biol. Chem. 273, 15445-15452
 |  Abstract »  |  Full Text »  |  PDF »

Polyomavirus Middle T Antigen as a Probe for T Cell Antigen Receptor-coupled Signaling Pathways.

A. P. Kennedy, A. Sekulic, B. J. Irvin, A. E. Nilson, S. M. Dilworth, and R. T. Abraham (1998)
J. Biol. Chem. 273, 11505-11513
 |  Abstract »  |  Full Text »  |  PDF »

One of the CD3{varepsilon} Subunits within a T Cell Receptor Complex Lies in Close Proximity to the C{beta} FG Loop.

Y. Ghendler, A. Smolyar, H.-C. Chang, and E. L. Reinherz (1998)
J. Exp. Med. 187, 1529-1536
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Signal Transduction Through the TCR-{zeta} Chain Following T Cell Stimulation with Analogue Peptides of Type II Collagen 260-267.

B. Tang, L. K. Myers, E. F. Rosloniec, K. B. Whittington, J. M. Stuart, and A. H. Kang (1998)
J. Immunol. 160, 3135-3142
 |  Abstract »  |  Full Text »  |  PDF »

Asymmetrical Phosphorylation and Function of Immunoreceptor Tyrosine-Based Activation Motif Tyrosines in B Cell Antigen Receptor Signal Transduction.

L. I. Pao, S. J. Famiglietti, and J. C. Cambier (1998)
J. Immunol. 160, 3305-3314
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Evidence for Differential Coupling of Syk Family Kinases to the T-Cell Receptor: Reconstitution Studies in a ZAP-70-Deficient Jurkat T-Cell Line.

B. L. Williams, K. L. Schreiber, W. Zhang, R. L. Wange, L. E. Samelson, P. J. Leibson, and R. T. Abraham (1998)
Mol. Cell. Biol. 18, 1388-1399
 |  Abstract »  |  Full Text »  |  PDF »

A High-Capacity Scintillation Proximity Assay for the Discovery and Evaluation of ZAP-70 Tandem SH2 Domain Antagonists.

M. P. Sheets, U. P. Warrior, H. Yoon, K. W. Mollison, S. W. Djuric, and J. M. Trevillyan (1998)
J Biomol Screen 3, 139-144
 |  Abstract »  |  PDF »

CD28 Receptor Endocytosis Is Targeted by Mutations That Disrupt Phosphatidylinositol 3-Kinase Binding and Costimulation.

D. Cefai, H. Schneider, O. Matangkasombut, H. Kang, J. Brody, and C. E. Rudd (1998)
J. Immunol. 160, 2223-2230
 |  Abstract »  |  Full Text »  |  PDF »

Cytoskeletal Polarization of T Cells Is Regulated by an Immunoreceptor Tyrosine-based Activation Motif-dependent Mechanism.

B. Lowin-Kropf, V. S. Shapiro, and A. Weiss (1998)
J. Cell Biol. 140, 861-871
 |  Abstract »  |  Full Text »  |  PDF »

Membrane Oligomerization and Cleavage Activates the Caspase-8 (FLICE/MACHalpha 1) Death Signal.

D. A. Martin, R. M. Siegel, L. Zheng, and M. J. Lenardo (1998)
J. Biol. Chem. 273, 4345-4349
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of TCR Signal Transduction in Murine Thymocytes by Multiple TCR {zeta}-Chain Signaling Motifs.

N. S. C. van Oers, P. E. Love, E. W. Shores, and A. Weiss (1998)
J. Immunol. 160, 163-170
 |  Abstract »  |  Full Text »  |  PDF »

Jun NH2-terminal kinase is constitutively activated in T cells transformed by the intracellular parasite Theileria parva.

Y. Galley, G. Hagens, I. Glaser, W. Davis, M. Eichhorn, and D. Dobbelaere (1997)
PNAS 94, 5119-5124
 |  Abstract »  |  Full Text »  |  PDF »

Biochemical Evidence That the Phosphorylated Tyrosines, Serines, and Threonines on the Aggregated High Affinity Receptor for IgE Are in the Immunoreceptor Tyrosine-based Activation Motifs.

V. S. Pribluda, C. Pribluda, and H. Metzger (1997)
J. Biol. Chem. 272, 11185-11192
 |  Abstract »  |  Full Text »  |  PDF »

Role of the Multiple T Cell Receptor (TCR)-{zeta} Chain Signaling Motifs in Selection of the T Cell Repertoire.

E. W. Shores, T. Tran, A. Grinberg, C. L. Sommers, H. Shen, and P. E. Love (1997)
J. Exp. Med. 185, 893-900
 |  Abstract »  |  Full Text »  |  PDF »

B-Cell Antigen Receptor-Induced Apoptosis Requires Both Igalpha and Igbeta.

J. Tseng, B. J. Eisfelder, and M. R. Clark (1997)
Blood 89, 1513-1520
 |  Abstract »  |  Full Text »  |  PDF »

Development and function of T cells in T cell antigen receptor/CD3 zeta  knockout mice reconstituted with Fcvarepsilon RI gamma.

C.-P. Liu, W.-J. Lin, M. Huang, J. W. Kappler, and P. Marrack (1997)
PNAS 94, 616-621
 |  Abstract »  |  Full Text »  |  PDF »

Differential Activation of the Tyrosine Kinases ZAP-70 and Syk After Fcgamma RI Stimulation.

N. Taylor, T. Jahn, S. Smith, T. Lamkin, L. Uribe, Y. Liu, D. L. Durden, and K. Weinberg (1997)
Blood 89, 388-396
 |  Abstract »  |  Full Text »  |  PDF »

Downstream Signaling Molecules Bind to Different Phosphorylated Immunoreceptor Tyrosine-based Activation Motif (ITAM) Peptides of the High Affinity IgE Receptor.

T. Kimura, H. Kihara, S. Bhattacharyya, H. Sakamoto, E. Appella, and R. P. Siraganian (1996)
J. Biol. Chem. 271, 27962-27968
 |  Abstract »  |  Full Text »  |  PDF »

The Cytoplasmic Tail of Fcgamma RIIIAalpha Is Involved in Signaling by the Low Affinity Receptor for Immunoglobulin G.

X. Hou, J. Dietrich, N. Odum, and C. Geisler (1996)
J. Biol. Chem. 271, 22815-22822
 |  Abstract »  |  Full Text »  |  PDF »

Purification and Characterization of Human ZAP-70 Protein-tyrosine Kinase from a Baculovirus Expression System.

N. Isakov, R. L. Wange, J. D. Watts, R. Aebersold, and L. E. Samelson (1996)
J. Biol. Chem. 271, 15753-15761
 |  Abstract »  |  Full Text »  |  PDF »

The Cytoplasmic Domain of Syndecan-1 Is Required for Cytoskeleton Association but Not Detergent Insolubility. IDENTIFICATION OF ESSENTIAL CYTOPLASMIC DOMAIN RESIDUES.

D. J. Carey, K. M. Bendt, and R. C. Stahl (1996)
J. Biol. Chem. 271, 15253-15260
 |  Abstract »  |  Full Text »  |  PDF »

SH2 Domain Function Is Essential for the Role of the Lck Tyrosine Kinase in T Cell Receptor Signal Transduction.

D. B. Straus, A. C. Chan, B. Patai, and A. Weiss (1996)
J. Biol. Chem. 271, 9976-9981
 |  Abstract »  |  Full Text »  |  PDF »

Two Distinct Intracytoplasmic Regions of the T-cell Adhesion Molecule CD28 Participate in Phosphatidylinositol 3-Kinase Association.

F.ço. Pagès, M. Ragueneau, S. Klasen, M. Battifora, D. Couez, R. Sweet, A. Truneh, S. G. Ward, and D. Olive (1996)
J. Biol. Chem. 271, 9403-9409
 |  Abstract »  |  Full Text »  |  PDF »

Specific Interaction of Topoisomerase IIbeta and the CD3[IMAGE] Chain of the T Cell Receptor Complex.

H. Nakano, T. Yamazaki, S. Miyatake, N. Nozaki, A. Kikuchi, and T. Saito (1996)
J. Biol. Chem. 271, 6483-6489
 |  Abstract »  |  Full Text »  |  PDF »

Cooperativity and Segregation of Function within the Ig-alpha/beta Heterodimer of the B Cell Antigen Receptor Complex.

P. Luisiri, Y. J. Lee, B. J. Eisfelder, and M. R. Clark (1996)
J. Biol. Chem. 271, 5158-5163
 |  Abstract »  |  Full Text »  |  PDF »

Self-association of N-Syndecan (Syndecan-3) Core Protein Is Mediated by a Novel Structural Motif in the Transmembrane Domain and Ectodomain Flanking Region.

V. K. Asundi and D. J. Carey (1995)
J. Biol. Chem. 270, 26404-26410
 |  Abstract »  |  Full Text »  |  PDF »

A Comparison of the Interaction of Shc and the Tyrosine Kinase ZAP-70 with the T Cell Antigen Receptor [IMAGE] Chain Tyrosine-based Activation Motif.

N. Osman, S. C. Lucas, H. Turner, and D. Cantrell (1995)
J. Biol. Chem. 270, 13981-13986
 |  Abstract »  |  Full Text »  |  PDF »

Syk Is Activated by Phosphotyrosine-containing Peptides Representing the Tyrosine-based Activation Motifs of the High Affinity Receptor for IgE.

L. Shiue, M. J. Zoller, and J. S. Brugge (1995)
J. Biol. Chem. 270, 10498-10502
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of the Adapter Molecule Grb2 by the Fc[IMAGE]R1 in the Mast Cell Line RBL2H3.

H. Turner, K. Reif, J. Rivera, and D. A. Cantrell (1995)
J. Biol. Chem. 270, 9500-9506
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Functions of the Fc[IMAGE]R1 [IMAGE] and beta Subunits in the Control of Fc[IMAGE]R1-mediated Tyrosine Kinase Activation and Signaling Responses in RBL-2H3 Mast Cells.

B. S. Wilson, N. Kapp, R. J. Lee, J. R. Pfeiffer, A. M. Martinez, Y. Platt, F. Letourneur, and J. M. Oliver (1995)
J. Biol. Chem. 270, 4013-4022
 |  Abstract »  |  Full Text »  |  PDF »

The Human Type 1 Inositol 1,4,5-Trisphosphate Receptor from T Lymphocytes.

D. J. Harnick, T. Jayaraman, Y. Ma, P. Mulieri, L. O. Go, and A. R. Marks (1995)
J. Biol. Chem. 270, 2833-2840
 |  Abstract »  |  Full Text »  |  PDF »

F(2)(Pmp)(2)-TAM[IMAGE](3), a Novel Competitive Inhibitor of the Binding of ZAP-70 to the T Cell Antigen Receptor, Blocks Early T Cell Signaling.

R. L. Wange, N. Isakov, T. R. Burke Jr., A. Otaka, P. P. Roller, J. D. Watts, R. Aebersold, and L. E. Samelson (1995)
J. Biol. Chem. 270, 944-948
 |  Abstract »  |  Full Text »  |  PDF »

Role of TCR zeta chain in T cell development and selection.

E. Shores, K Huang, T Tran, E Lee, A Grinberg, and P. Love (1994)
Science 266, 1047-1050
 |  Abstract »  |  PDF »

Sequential interactions of the TCR with two distinct cytoplasmic tyrosine kinases.

M Iwashima, B. Irving, N. van Oers, A. Chan, and A Weiss (1994)
Science 263, 1136-1139
 |  Abstract »  |  PDF »

Interaction of Shc with the zeta chain of the T cell receptor upon T cell activation.

K. Ravichandran, K. Lee, Z Songyang, L. Cantley, P Burn, and S. Burakoff (1993)
Science 262, 902-905
 |  Abstract »  |  PDF »

Reconstitution of T cell receptor zeta-mediated calcium mobilization in nonlymphoid cells.

C. Hall, J Sancho, and C Terhorst (1993)
Science 261, 915-918
 |  Abstract »  |  PDF »

The B cell antigen receptor complex: association of Ig-alpha and Ig-beta with distinct cytoplasmic effectors.

M. Clark, K. Campbell, A Kazlauskas, S. Johnson, M Hertz, T. Potter, C Pleiman, and J. Cambier (1992)
Science 258, 123-126
 |  Abstract »  |  PDF »

Regulation of Protein Tyrosine Kinase Activation by the T-cell Antigen Receptor {zeta} Chain.

A. Weiss, A.C. Chan, M. Iwashima, D. Straus, and B.A. Irving (1992)
Cold Spring Harb Symp Quant Biol 57, 107-116
 |  Abstract »  |  PDF »

Activation of Immune System Effector Function by T-cell or Fc Receptor Intracellular Domains.

C. Romeo, W. Kolanus, M. Amiot, and B. Seed (1992)
Cold Spring Harb Symp Quant Biol 57, 117-125
 |  Abstract »  |  PDF »

Intracellular Redistribution of Nucleolin upon Interaction with the CD3epsilon Chain of the T Cell Receptor Complex.

D. Gil, D. Gutierrez, and B. Alarcon (2001)
J. Biol. Chem. 276, 11174-11179
 |  Abstract »  |  Full Text »  |  PDF »

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