Science 13 December 1991: Vol. 254. no. 5038, pp. 1598 - 1603 DOI: 10.1126/science.1749933

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Articles

Non-genetic heterogeneity of cells in development: more than just noise.

S. Huang (2009)
Development 136, 3853-3862
 |  Abstract »  |  Full Text »  |  PDF »

Ligand and Substrate Migration in Human Indoleamine 2,3-Dioxygenase.

E. Nickel, K. Nienhaus, C. Lu, S.-R. Yeh, and G. U. Nienhaus (2009)
J. Biol. Chem. 284, 31548-31554
 |  Abstract »  |  Full Text »  |  PDF »

How to mark off paths on the protein energy landscape.

M. Gruebele (2009)
PNAS 106, 18879-18880
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Single-molecule analysis reveals that the lagging strand increases replisome processivity but slows replication fork progression.

N. Y. Yao, R. E. Georgescu, J. Finkelstein, and M. E. O'Donnell (2009)
PNAS 106, 13236-13241
 |  Abstract »  |  Full Text »  |  PDF »

Using dynamics-based comparisons to predict nucleic acid binding sites in proteins: an application to OB-fold domains.

A. Zen, C. de Chiara, A. Pastore, and C. Micheletti (2009)
Bioinformatics 25, 1876-1883
 |  Abstract »  |  Full Text »  |  PDF »

Protein dynamics-induced variation of excitation energy transfer pathways.

M. Brecht, V. Radics, J. B. Nieder, and R. Bittl (2009)
PNAS 106, 11857-11861
 |  Abstract »  |  Full Text »  |  PDF »

Direct single-molecule observation of a protein living in two opposed native structures.

Y. Gambin, A. Schug, E. A. Lemke, J. J. Lavinder, A. C. M. Ferreon, T. J. Magliery, J. N. Onuchic, and A. A. Deniz (2009)
PNAS 106, 10153-10158
 |  Abstract »  |  Full Text »  |  PDF »

Sending Signals Dynamically.

R. G. Smock and L. M. Gierasch (2009)
Science 324, 198-203
 |  Abstract »  |  Full Text »  |  PDF »

A unified model of protein dynamics.

H. Frauenfelder, G. Chen, J. Berendzen, P. W. Fenimore, H. Jansson, B. H. McMahon, I. R. Stroe, J. Swenson, and R. D. Young (2009)
PNAS 106, 5129-5134
 |  Abstract »  |  Full Text »  |  PDF »

Local conformational dynamics in {alpha}-helices measured by fast triplet transfer.

B. Fierz, A. Reiner, and T. Kiefhaber (2009)
PNAS 106, 1057-1062
 |  Abstract »  |  Full Text »  |  PDF »

DNA energy landscapes via calorimetric detection of microstate ensembles of metastable macrostates and triplet repeat diseases.

J. Volker, H. H. Klump, and K. J. Breslauer (2008)
PNAS 105, 18326-18330
 |  Abstract »  |  Full Text »  |  PDF »

Computing the stability diagram of the Trp-cage miniprotein.

D. Paschek, S. Hempel, and A. E. Garcia (2008)
PNAS 105, 17754-17759
 |  Abstract »  |  Full Text »  |  PDF »

Seven Transmembrane Receptors as Nature's Prototype Allosteric Protein: De-emphasizing the Geography of Binding.

T. P. Kenakin (2008)
Mol. Pharmacol. 74, 541-543
 |  Abstract »  |  Full Text »  |  PDF »

Potential landscape and flux framework of nonequilibrium networks: Robustness, dissipation, and coherence of biochemical oscillations.

J. Wang, L. Xu, and E. Wang (2008)
PNAS 105, 12271-12276
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of actin structure and function by phosphorylation of Tyr-53 and profilin binding.

K. Baek, X. Liu, F. Ferron, S. Shu, E. D. Korn, and R. Dominguez (2008)
PNAS 105, 11748-11753
 |  Abstract »  |  Full Text »  |  PDF »

Shoot-and-Trap: Use of specific x-ray damage to study structural protein dynamics by temperature-controlled cryo-crystallography.

J.-P. Colletier, D. Bourgeois, B. Sanson, D. Fournier, J. L. Sussman, I. Silman, and M. Weik (2008)
PNAS 105, 11742-11747
 |  Abstract »  |  Full Text »  |  PDF »

Dynamic energy landscape view of coupled binding and protein conformational change: Induced-fit versus population-shift mechanisms.

K.-i. Okazaki and S. Takada (2008)
PNAS 105, 11182-11187
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Hierarchical organization of eglin c native state dynamics is shaped by competing direct and water-mediated interactions.

C. K. Materese, C. C. Goldmon, and G. A. Papoian (2008)
PNAS 105, 10659-10664
 |  Abstract »  |  Full Text »  |  PDF »

Competing interactions create functionality through frustration.

V. Lubchenko (2008)
PNAS 105, 10635-10636
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Extracting function from a {beta}-trefoil folding motif.

S. Gosavi, P. C. Whitford, P. A. Jennings, and J. N. Onuchic (2008)
PNAS 105, 10384-10389
 |  Abstract »  |  Full Text »  |  PDF »

Direct observation of fast protein conformational switching.

H. Ishikawa, K. Kwak, J. K. Chung, S. Kim, and M. D. Fayer (2008)
PNAS 105, 8619-8624
 |  Abstract »  |  Full Text »  |  PDF »

Being uncomfortable..

P. A. Robbins, B. Suki, J. J. Fredberg, F. E. Yates, J. H. T. Bates, T. Similowski, L. Glass, and A. J. E. Seely (2008)
J Appl Physiol 104, 1848-1849
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Multiscale complex network of protein conformational fluctuations in single-molecule time series.

C.-B. Li, H. Yang, and T. Komatsuzaki (2008)
PNAS 105, 536-541
 |  Abstract »  |  Full Text »  |  PDF »

Localizing frustration in native proteins and protein assemblies.

D. U. Ferreiro, J. A. Hegler, E. A. Komives, and P. G. Wolynes (2007)
PNAS 104, 19819-19824
 |  Abstract »  |  Full Text »  |  PDF »

Construction of effective free energy landscape from single-molecule time series.

A. Baba and T. Komatsuzaki (2007)
PNAS 104, 19297-19302
 |  Abstract »  |  Full Text »  |  PDF »

Coupling of protein and hydration-water dynamics in biological membranes.

K. Wood, M. Plazanet, F. Gabel, B. Kessler, D. Oesterhelt, D. J. Tobias, G. Zaccai, and M. Weik (2007)
PNAS 104, 18049-18054
 |  Abstract »  |  Full Text »  |  PDF »

Illuminating the mechanistic roles of enzyme conformational dynamics.

J. A. Hanson, K. Duderstadt, L. P. Watkins, S. Bhattacharyya, J. Brokaw, J.-W. Chu, and H. Yang (2007)
PNAS 104, 18055-18060
 |  Abstract »  |  Full Text »  |  PDF »

Mutations as trapdoors to two competing native conformations of the Rop-dimer.

A. Schug, P. C. Whitford, Y. Levy, and J. N. Onuchic (2007)
PNAS 104, 17674-17679
 |  Abstract »  |  Full Text »  |  PDF »

Configuration-dependent diffusion can shift the kinetic transition state and barrier height of protein folding.

J. Chahine, R. J. Oliveira, V. B. P. Leite, and J. Wang (2007)
PNAS 104, 14646-14651
 |  Abstract »  |  Full Text »  |  PDF »

Protein folding and unfolding studied at atomic resolution by fast two-dimensional NMR spectroscopy.

P. Schanda, V. Forge, and B. Brutscher (2007)
PNAS 104, 11257-11262
 |  Abstract »  |  Full Text »  |  PDF »

Bacteriorhodopsin photocycle at cryogenic temperatures reveals distributed barriers of conformational substates.

A. K. Dioumaev and J. K. Lanyi (2007)
PNAS 104, 9621-9626
 |  Abstract »  |  Full Text »  |  PDF »

Molecular evolution of affinity and flexibility in the immune system.

I. F. Thorpe and C. L. Brooks III (2007)
PNAS 104, 8821-8826
 |  Abstract »  |  Full Text »  |  PDF »

Signatures of hydrophobic collapse in extended proteins captured with force spectroscopy.

K. A. Walther, F. Grater, L. Dougan, C. L. Badilla, B. J. Berne, and J. M. Fernandez (2007)
PNAS 104, 7916-7921
 |  Abstract »  |  Full Text »  |  PDF »

Influence of the Redox Potential of the Primary Quinone Electron Acceptor on Photoinhibition in Photosystem II.

C. Fufezan, C. M. Gross, M. Sjodin, A. W. Rutherford, A. Krieger-Liszkay, and D. Kirilovsky (2007)
J. Biol. Chem. 282, 12492-12502
 |  Abstract »  |  Full Text »  |  PDF »

Dissection of complex protein dynamics in human thioredoxin.

W. Qiu, L. Wang, W. Lu, A. Boechler, D. A. R. Sanders, and D. Zhong (2007)
PNAS 104, 5366-5371
 |  Abstract »  |  Full Text »  |  PDF »

Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin.

C. Zong, C. J. Wilson, T. Shen, P. Wittung-Stafshede, S. L. Mayo, and P. G. Wolynes (2007)
PNAS 104, 3159-3164
 |  Abstract »  |  Full Text »  |  PDF »

Loop formation in unfolded polypeptide chains on the picoseconds to microseconds time scale.

B. Fierz, H. Satzger, C. Root, P. Gilch, W. Zinth, and T. Kiefhaber (2007)
PNAS 104, 2163-2168
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Complex network analysis of free-energy landscapes.

D. Gfeller, P. De Los Rios, A. Caflisch, and F. Rao (2007)
PNAS 104, 1817-1822
 |  Abstract »  |  Full Text »  |  PDF »

Inaugural Article: Connecting nitrogenase intermediates with the kinetic scheme for N2 reduction by a relaxation protocol and identification of the N2 binding state.

D. Lukoyanov, B. M. Barney, D. R. Dean, L. C. Seefeldt, and B. M. Hoffman (2007)
PNAS 104, 1451-1455
 |  Abstract »  |  Full Text »  |  PDF »

A backbone-based theory of protein folding.

G. D. Rose, P. J. Fleming, J. R. Banavar, and A. Maritan (2006)
PNAS 103, 16623-16633
 |  Abstract »  |  Full Text »  |  PDF »

Protein complex formation by acetylcholinesterase and the neurotoxin fasciculin-2 appears to involve an induced-fit mechanism.

J. M. Bui and J. A. McCammon (2006)
PNAS 103, 15451-15456
 |  Abstract »  |  Full Text »  |  PDF »

Protein folding is slaved to solvent motions.

H. Frauenfelder, P. W. Fenimore, G. Chen, and B. H. McMahon (2006)
PNAS 103, 15469-15472
 |  Abstract »  |  Full Text »  |  PDF »

Two ligand-binding sites in the O2-sensing signal transducer HemAT: Implications for ligand recognition/discrimination and signaling.

E. Pinakoulaki, H. Yoshimura, V. Daskalakis, S. Yoshioka, S. Aono, and C. Varotsis (2006)
PNAS 103, 14796-14801
 |  Abstract »  |  Full Text »  |  PDF »

Antibody evolution constrains conformational heterogeneity by tailoring protein dynamics.

J. Zimmermann, E. L. Oakman, I. F. Thorpe, X. Shi, P. Abbyad, C. L. Brooks III, S. G. Boxer, and F. E. Romesberg (2006)
PNAS 103, 13722-13727
 |  Abstract »  |  Full Text »  |  PDF »

Hierarchic Finite Level Energy Landscape Model: TO DESCRIBE THE REFOLDING KINETICS OF PHOSPHOGLYCERATE KINASE.

S. Osvath, L. Herenyi, P. Zavodszky, J. Fidy, and G. Kohler (2006)
J. Biol. Chem. 281, 24375-24380
 |  Abstract »  |  Full Text »  |  PDF »

Complementarity of ensemble and single-molecule measures of protein motion: A relaxation dispersion NMR study of an enzyme complex.

P. Vallurupalli and L. E. Kay (2006)
PNAS 103, 11910-11915
 |  Abstract »  |  Full Text »  |  PDF »

A two-dimensional view of the folding energy landscape of cytochrome c.

J. H. Werner, R. Joggerst, R. B. Dyer, and P. M. Goodwin (2006)
PNAS 103, 11130-11135
 |  Abstract »  |  Full Text »  |  PDF »

The inherent structure landscape of a protein.

N. Nakagawa and M. Peyrard (2006)
PNAS 103, 5279-5284
 |  Abstract »  |  Full Text »  |  PDF »

Extended subnanosecond structural dynamics of myoglobin revealed by Laue crystallography.

D. Bourgeois, B. Vallone, A. Arcovito, G. Sciara, F. Schotte, P. A. Anfinrud, and M. Brunori (2006)
PNAS 103, 4924-4929
 |  Abstract »  |  Full Text »  |  PDF »

Novel Conformational States of Peptide Deformylase from Pathogenic Bacterium Leptospira interrogans: IMPLICATIONS FOR POPULATION SHIFT.

Z. Zhou, X. Song, and W. Gong (2005)
J. Biol. Chem. 280, 42391-42396
 |  Abstract »  |  Full Text »  |  PDF »

The Position 68(E11) Side Chain in Myoglobin Regulates Ligand Capture, Bond Formation with Heme Iron, and Internal Movement into the Xenon Cavities.

D. Dantsker, C. Roche, U. Samuni, G. Blouin, J. S. Olson, and J. M. Friedman (2005)
J. Biol. Chem. 280, 38740-38755
 |  Abstract »  |  Full Text »  |  PDF »

Conformational dependence of a protein kinase phosphate transfer reaction.

G. Henkelman, M. X. LaBute, C.-S. Tung, P. W. Fenimore, and B. H. McMahon (2005)
PNAS 102, 15347-15351
 |  Abstract »  |  Full Text »  |  PDF »

Single-molecule Forster resonance energy transfer study of protein dynamics under denaturing conditions.

E. V. Kuzmenkina, C. D. Heyes, and G. U. Nienhaus (2005)
PNAS 102, 15471-15476
 |  Abstract »  |  Full Text »  |  PDF »

Identification of slow correlated motions in proteins using residual dipolar and hydrogen-bond scalar couplings.

G. Bouvignies, P. Bernado, S. Meier, K. Cho, S. Grzesiek, R. Bruschweiler, and M. Blackledge (2005)
PNAS 102, 13885-13890
 |  Abstract »  |  Full Text »  |  PDF »

Pre-Unfolding Resonant Oscillations of Single Green Fluorescent Protein Molecules.

G. Baldini, F. Cannone, and G. Chirico (2005)
Science 309, 1096-1100
 |  Abstract »  |  Full Text »  |  PDF »

Functional conformational motions in the turnover cycle of cholesterol oxidase.

H.-P. Lerch, R. Rigler, and A. S. Mikhailov (2005)
PNAS 102, 10807-10812
 |  Abstract »  |  Full Text »  |  PDF »

Gating of proton and water transfer in the respiratory enzyme cytochrome c oxidase.

M. Wikstrom, C. Ribacka, M. Molin, L. Laakkonen, M. Verkhovsky, and A. Puustinen (2005)
PNAS 102, 10478-10481
 |  Abstract »  |  Full Text »  |  PDF »

History-Dependent Multiple-Time-Scale Dynamics in a Single-Neuron Model.

G. Gilboa, R. Chen, and N. Brenner (2005)
J. Neurosci. 25, 6479-6489
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Human myoglobin recognition of oxygen: Dynamics of the energy landscape.

Y. Wang, J. S. Baskin, T. Xia, and A. H. Zewail (2004)
PNAS 101, 18000-18005
 |  Abstract »  |  Full Text »  |  PDF »

Unveiling functional protein motions with picosecond x-ray crystallography and molecular dynamics simulations.

G. Hummer, F. Schotte, and P. A. Anfinrud (2004)
PNAS 101, 15330-15334
 |  Abstract »  |  Full Text »  |  PDF »

Dynamical transition and proteinquake in photoactive yellow protein.

K. Itoh and M. Sasai (2004)
PNAS 101, 14736-14741
 |  Abstract »  |  Full Text »  |  PDF »

Bulk-solvent and hydration-shell fluctuations, similar to {alpha}- and {beta}-fluctuations in glasses, control protein motions and functions.

P. W. Fenimore, H. Frauenfelder, B. H. McMahon, and R. D. Young (2004)
PNAS 101, 14408-14413
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Domain swapping is a consequence of minimal frustration.

S. Yang, S. S. Cho, Y. Levy, M. S. Cheung, H. Levine, P. G. Wolynes, and J. N. Onuchic (2004)
PNAS 101, 13786-13791
 |  Abstract »  |  Full Text »  |  PDF »

Viscosity-dependent Relaxation Significantly Modulates the Kinetics of CO Recombination in the Truncated Hemoglobin TrHbN from Mycobacterium tuberculosis.

D. Dantsker, U. Samuni, Y. Ouellet, B. A. Wittenberg, J. B. Wittenberg, M. Milani, M. Bolognesi, M. Guertin, and J. M. Friedman (2004)
J. Biol. Chem. 279, 38844-38853
 |  Abstract »  |  Full Text »  |  PDF »

A single-amino-acid lid renders a gas-tight compartment within a membrane-bound transporter.

L. Salomonsson, A. Lee, R. B. Gennis, and P. Brzezinski (2004)
PNAS 101, 11617-11621
 |  Abstract »  |  Full Text »  |  PDF »

Allosteric Modulators: The New Generation of Receptor Antagonist.

T. Kenakin (2004)
Mol. Interv. 4, 222-229
 |  Abstract »  |  Full Text »  |  PDF »

Thermal-activated protein mobility and its correlation with catalysis in thermophilic alcohol dehydrogenase.

Z.-X. Liang, T. Lee, K. A. Resing, N. G. Ahn, and J. P. Klinman (2004)
PNAS 101, 9556-9561
 |  Abstract »  |  Full Text »  |  PDF »

Analytic models for mechanotransduction: Gating a mechanosensitive channel.

P. Wiggins and R. Phillips (2004)
PNAS 101, 4071-4076
 |  Abstract »  |  Full Text »  |  PDF »

Diversity in the Rates of Transcript Elongation by Single RNA Polymerase Molecules.

S. F. Tolic-Norrelykke, A. M. Engh, R. Landick, and J. Gelles (2004)
J. Biol. Chem. 279, 3292-3299
 |  Abstract »  |  Full Text »  |  PDF »

Direct observation of tiers in the energy landscape of a chromoprotein: A single-molecule study.

C. Hofmann, T. J. Aartsma, H. Michel, and J. Kohler (2003)
PNAS 100, 15534-15538
 |  Abstract »  |  Full Text »  |  PDF »

Adhesive-cohesive model for protein compressibility: An alternative perspective on stability.

V. M. Dadarlat and C. B. Post (2003)
PNAS 100, 14778-14783
 |  Abstract »  |  Full Text »  |  PDF »

Nonlinear elasticity, proteinquakes, and the energy landscapes of functional transitions in proteins.

O. Miyashita, J. N. Onuchic, and P. G. Wolynes (2003)
PNAS 100, 12570-12575
 |  Abstract »  |  Full Text »  |  PDF »

Noise and stochastic resonance in voltage-gated ion channels.

R. K. Adair (2003)
PNAS 100, 12099-12104
 |  Abstract »  |  Full Text »  |  PDF »

Protein Conformational Dynamics Probed by Single-Molecule Electron Transfer.

H. Yang, G. Luo, P. Karnchanaphanurach, T.-M. Louie, I. Rech, S. Cova, L. Xun, and X. S. Xie (2003)
Science 302, 262-266
 |  Abstract »  |  Full Text »  |  PDF »

Docking Site Dynamics of ba3-Cytochrome c Oxidase from Thermus thermophilus.

C. Koutsoupakis, T. Soulimane, and C. Varotsis (2003)
J. Biol. Chem. 278, 36806-36809
 |  Abstract »  |  Full Text »  |  PDF »

Hydrogen atoms in proteins: Positions and dynamics.

N. Engler, A. Ostermann, N. Niimura, and F. G. Parak (2003)
PNAS 100, 10243-10248
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Mechanisms and Therapeutical Implications of Intramembrane Receptor/Receptor Interactions among Heptahelical Receptors with Examples from the Striatopallidal GABA Neurons.

L. F. Agnati, S. Ferre, C. Lluis, R. Franco, and K. Fuxe (2003)
Pharmacol. Rev. 55, 509-550
 |  Abstract »  |  Full Text »  |  PDF »

Single-Molecule Kinetics of {lambda} Exonuclease Reveal Base Dependence and Dynamic Disorder.

A. M. van Oijen, P. C. Blainey, D. J. Crampton, C. C. Richardson, T. Ellenberger, and X. S. Xie (2003)
Science 301, 1235-1238
 |  Abstract »  |  Full Text »  |  PDF »

Myoglobin: The hydrogen atom of biology and a paradigm of complexity.

H. Frauenfelder, B. H. McMahon, and P. W. Fenimore (2003)
PNAS 100, 8615-8617
 |  Full Text »  |  PDF »

Complex landscape of protein structural dynamics unveiled by nanosecond Laue crystallography.

D. Bourgeois, B. Vallone, F. Schotte, A. Arcovito, A. E. Miele, G. Sciara, M. Wulff, P. Anfinrud, and M. Brunori (2003)
PNAS 100, 8704-8709
 |  Abstract »  |  Full Text »  |  PDF »

Fast gating in the Shaker K+ channel and the energy landscape of activation.

D. Sigg, F. Bezanilla, and E. Stefani (2003)
PNAS 100, 7611-7615
 |  Abstract »  |  Full Text »  |  PDF »

Picosecond conformational transition and equilibration of a cyclic peptide.

J. Bredenbeck, J. Helbing, A. Sieg, T. Schrader, W. Zinth, C. Renner, R. Behrendt, L. Moroder, J. Wachtveitl, and P. Hamm (2003)
PNAS 100, 6452-6457
 |  Abstract »  |  Full Text »  |  PDF »

Buffed energy landscapes: Another solution to the kinetic paradoxes of protein folding.

S. S. Plotkin and P. G. Wolynes (2003)
PNAS 100, 4417-4422
 |  Abstract »  |  Full Text »  |  PDF »

Slaving: Solvent fluctuations dominate protein dynamics and functions.

P. W. Fenimore, H. Frauenfelder, B. H. McMahon, and F. G. Parak (2002)
PNAS 99, 16047-16051
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: Probing the folding free energy landscape of the src-SH3 protein domain.

J.-E. Shea, J. N. Onuchic, and C. L. Brooks III (2002)
PNAS 99, 16064-16068
 |  Abstract »  |  Full Text »  |  PDF »

Conformational-relaxation models of single-enzyme kinetics.

H.-P. Lerch, A. S. Mikhailov, and B. Hess (2002)
PNAS 99, 15410-15415
 |  Abstract »  |  Full Text »  |  PDF »

Folding free energy function selects native-like protein sequences in the core but not on the surface.

A. Jaramillo, L. Wernisch, S. Hery, and S. J. Wodak (2002)
PNAS 99, 13554-13559
 |  Abstract »  |  Full Text »  |  PDF »

Spectroscopically and Kinetically Distinct Conformational Populations of Sol-Gel-encapsulated Carbonmonoxy Myoglobin. A COMPARISON WITH HEMOGLOBIN.

U. Samuni, D. Dantsker, I. Khan, A. J. Friedman, E. Peterson, and J. M. Friedman (2002)
J. Biol. Chem. 277, 25783-25790
 |  Abstract »  |  Full Text »  |  PDF »

Ultrafast spectroscopy reveals subnanosecond peptide conformational dynamics and validates molecular dynamics simulation.

S. Sporlein, H. Carstens, H. Satzger, C. Renner, R. Behrendt, L. Moroder, P. Tavan, W. Zinth, and J. Wachtveitl (2002)
PNAS 99, 7998-8002
 |  Abstract »  |  Full Text »  |  PDF »

Ligand binding and protein dynamics in neuroglobin.

J. M. Kriegl, A. J. Bhattacharyya, K. Nienhaus, P. Deng, O. Minkow, and G. U. Nienhaus (2002)
PNAS 99, 7992-7997
 |  Abstract »  |  Full Text »  |  PDF »

G Protein-Coupled Receptor Allosterism and Complexing.

A. Christopoulos and T. Kenakin (2002)
Pharmacol. Rev. 54, 323-374
 |  Abstract »  |  Full Text »  |  PDF »

Gaussian fluctuations and linear response in an electron transfer protein.

T. Simonson (2002)
PNAS 99, 6544-6549
 |  Abstract »  |  Full Text »  |  PDF »

Structural Dynamics of Myoglobin. LIGAND MIGRATION AMONG PROTEIN CAVITIES STUDIED BY FOURIER TRANSFORM INFRARED/TEMPERATURE DERIVATIVE SPECTROSCOPY.

D. C. Lamb, K. Nienhaus, A. Arcovito, F. Draghi, A. E. Miele, M. Brunori, and G. U. Nienhaus (2002)
J. Biol. Chem. 277, 11636-11644
 |  Abstract »  |  Full Text »  |  PDF »

Ion channel gating: A first-passage time analysis of the Kramers type.

I. Goychuk and P. Hanggi (2002)
PNAS 99, 3552-3556
 |  Abstract »  |  Full Text »  |  PDF »

Proteins: Paradigms of complexity.

H. Frauenfelder (2002)
PNAS 99, 2479-2480
 |  Abstract »  |  Full Text »  |  PDF »

On the nature of a glassy state of matter in a hydrated protein: Relation to protein function.

M. M. Teeter, A. Yamano, B. Stec, and U. Mohanty (2001)
PNAS 98, 11242-11247
 |  Abstract »  |  Full Text »  |  PDF »

Inverse, protean, and ligand-selective agonism: matters of receptor conformation.

T. KENAKIN (2001)
FASEB J 15, 598-611
 |  Abstract »  |  Full Text »  |  PDF »

Solvent dependence of dynamic transitions in protein solutions.

V. Reat, R. Dunn, M. Ferrand, J. L. Finney, R. M. Daniel, and J. C. Smith (2000)
PNAS 97, 9961-9966
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