Science 27 September 1991: Vol. 253. no. 5027, pp. 1550 - 1553 DOI: 10.1126/science.1654597

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Articles

Divergent Transforming Growth Factor-{beta} Signaling in Hepatic Stellate Cells after Liver Injury: Functional Effects on ECE-1 Regulation.

A.-k. Khimji, R. Shao, and D. C. Rockey (2008)
Am. J. Pathol. 173, 716-727
 |  Abstract »  |  Full Text »  |  PDF »

New insights into the function of the Wilms tumor suppressor gene WT1 in podocytes.

A. A. Morrison, R. L. Viney, M. A. Saleem, and M. R. Ladomery (2008)
Am J Physiol Renal Physiol 295, F12-F17
 |  Abstract »  |  Full Text »  |  PDF »

Vertebrate heart growth is regulated by functional antagonism between Gridlock and Gata5.

H. Jia, I. N. King, S. S. Chopra, H. Wan, T. T. Ni, C. Jiang, X. Guan, S. Wells, D. Srivastava, and T. P. Zhong (2007)
PNAS 104, 14008-14013
 |  Abstract »  |  Full Text »  |  PDF »

The Transcription Factor Wilms Tumor 1 Regulates Matrix Metalloproteinase-9 through a Nitric Oxide-Mediated Pathway.

M. Marcet-Palacios, M. Ulanova, F. Duta, L. Puttagunta, S. Munoz, D. Gibbings, M. Radomski, L. Cameron, I. Mayers, and A. D. Befus (2007)
J. Immunol. 179, 256-265
 |  Abstract »  |  Full Text »  |  PDF »

The Role of MAPKs in B Cell Receptor-induced Down-regulation of Egr-1 in Immature B Lymphoma Cells.

J. Ke, M. Gururajan, A. Kumar, A. Simmons, L. Turcios, R. L. Chelvarajan, D. M. Cohen, D. L. Wiest, J. G. Monroe, and S. Bondada (2006)
J. Biol. Chem. 281, 39806-39818
 |  Abstract »  |  Full Text »  |  PDF »

Wilms' Tumor 1 and Signal Transducers and Activators of Transcription 3 Synergistically Promote Cell Proliferation: A Possible Mechanism in Sporadic Wilms' Tumor.

Y. Rong, L. Cheng, H. Ning, J. Zou, Y. Zhang, F. Xu, L. Liu, Z. Chang, and X.-Y. Fu (2006)
Cancer Res. 66, 8049-8057
 |  Abstract »  |  Full Text »  |  PDF »

Mechanical Stretch Modulates the Promoter Activity of the Profibrotic Factor CCN2 through Increased Actin Polymerization and NF-{kappa}B Activation.

B. Chaqour, R. Yang, and Q. Sha (2006)
J. Biol. Chem. 281, 20608-20622
 |  Abstract »  |  Full Text »  |  PDF »

WT1 Induces Apoptosis through Transcriptional Regulation of the Proapoptotic Bcl-2 Family Member Bak.

D. J. Morrison, M. A. English, and J. D. Licht (2005)
Cancer Res. 65, 8174-8182
 |  Abstract »  |  Full Text »  |  PDF »

Expression, Regulation, and Function of Paired-Box Gene 8 in the Human Placenta and Placental Cancer Cell Lines.

E. Ferretti, F. Arturi, T. Mattei, A. Scipioni, G. Tell, E. Tosi, I. Presta, R. Morisi, L. Lacroix, A. Gulino, et al. (2005)
Endocrinology 146, 4009-4015
 |  Abstract »  |  Full Text »  |  PDF »

The WT1 Wilms' tumor suppressor gene product interacts with estrogen receptor-{alpha} and regulates IGF-I receptor gene transcription in breast cancer cells.

N. Reizner, S. Maor, R. Sarfstein, S. Abramovitch, W. V Welshons, E. M Curran, A. V Lee, and H. Werner (2005)
J. Mol. Endocrinol. 35, 135-144
 |  Abstract »  |  Full Text »  |  PDF »

Egr-1 negatively regulates expression of the sodium-calcium exchanger-1 in cardiomyocytes in vitro and in vivo.

C. Wang, S. Dostanic, N. Servant, and L. E. Chalifour (2005)
Cardiovasc Res 65, 187-194
 |  Abstract »  |  Full Text »  |  PDF »

The role of nuclear Y-box binding protein 1 as a global marker in drug resistance.

M. Kuwano, Y. Oda, H. Izumi, S.-J. Yang, T. Uchiumi, Y. Iwamoto, M. Toi, T. Fujii, H. Yamana, H. Kinoshita, et al. (2004)
Mol. Cancer Ther. 3, 1485-1492
 |  Abstract »  |  Full Text »  |  PDF »

BASP1 Is a Transcriptional Cosuppressor for the Wilms' Tumor Suppressor Protein WT1.

B. Carpenter, K. J. Hill, M. Charalambous, K. J. Wagner, D. Lahiri, D. I. James, J. S. Andersen, V. Schumacher, B. Royer-Pokora, M. Mann, et al. (2004)
Mol. Cell. Biol. 24, 537-549
 |  Abstract »  |  Full Text »  |  PDF »

Progesterone Up-Regulates WT1 mRna and Protein, and Alters the Relsative Expression of WT1 Transcripts in Cultured Endometrial Stromal Cells.

F. W. Anthony, D. D. Mukhtar, M. A. Pickett, and I. T. Cameron (2003)
Reproductive Sciences 10, 509-516
 |  Abstract »  |  PDF »

The WT1 Wilms' Tumor Suppressor Gene: A Novel Target for Insulin-Like Growth Factor-I Action.

I. Bentov, D. LeRoith, and H. Werner (2003)
Endocrinology 144, 4276-4279
 |  Abstract »  |  Full Text »  |  PDF »

Functional Analysis of RF2a, a Rice Transcription Factor.

S. Dai, S. Petruccelli, M. I. Ordiz, Z. Zhang, S. Chen, and R. N. Beachy (2003)
J. Biol. Chem. 278, 36396-36402
 |  Abstract »  |  Full Text »  |  PDF »

Regulated recruitment of HP1 to a euchromatic gene induces mitotically heritable, epigenetic gene silencing: a mammalian cell culture model of gene variegation.

K. Ayyanathan, M. S. Lechner, P. Bell, G. G. Maul, D. C. Schultz, Y. Yamada, K. Tanaka, K. Torigoe, and F. J. Rauscher III (2003)
Genes & Dev. 17, 1855-1869
 |  Abstract »  |  Full Text »  |  PDF »

Egr-1 Mediates Transcriptional Repression of COL2A1 Promoter Activity by Interleukin-1beta.

L. Tan, H. Peng, M. Osaki, B. K. Choy, P. E. Auron, L. J. Sandell, and M. B. Goldring (2003)
J. Biol. Chem. 278, 17688-17700
 |  Abstract »  |  Full Text »  |  PDF »

Biochemical Function of Female-Lethal (2)D/Wilms' Tumor Suppressor-1-associated Proteins in Alternative Pre-mRNA Splicing.

A. Ortega, M. Niksic, A. Bachi, M. Wilm, L. Sanchez, N. Hastie, and J. Valcarcel (2003)
J. Biol. Chem. 278, 3040-3047
 |  Abstract »  |  Full Text »  |  PDF »

Early Growth Response Transcription Factors Are Required for Development of CD4-CD8- Thymocytes to the CD4+CD8+ Stage.

M. Carleton, M. C. Haks, S. A. A. Smeele, A. Jones, S. M. Belkowski, M. A. Berger, P. Linsley, A. M. Kruisbeek, and D. L. Wiest (2002)
J. Immunol. 168, 1649-1658
 |  Abstract »  |  Full Text »  |  PDF »

Functional characterization of WT1 binding sites within the human vitamin D receptor gene promoter.

T. H. LEE and J. PELLETIER (2001)
Physiol Genomics 7, 187-200
 |  Abstract »  |  Full Text »  |  PDF »

Par4 is a coactivator for a splice isoform-specific transcriptional activation domain in WT1.

D. J. Richard, V. Schumacher, B. Royer-Pokora, and S. G.E. Roberts (2001)
Genes & Dev. 15, 328-339
 |  Abstract »  |  Full Text »

Expression and Prognostic Value of Wilms' Tumor 1 and Early Growth Response 1 Proteins in Nephroblastoma.

M. A. Ghanem, T. H. Van der Kwast, J. C. Den Hollander, M. K. Sudaryo, M. H. A. Oomen, M. A. Noordzij, M. M. Van den Heuvel, S. M. Nassef, R. M. Nijman, and G. J. Van Steenbrugge (2000)
Clin. Cancer Res. 6, 4265-4271
 |  Abstract »  |  Full Text »  |  PDF »

Hormone-dependent Tumor Regression in Vivo by an Inducible Transcriptional Repressor Directed at the PAX3-FKHR Oncogene.

K. Ayyanathan, W. J. Fredericks, C. Berking, M. Herlyn, C. Balakrishnan, E. Gunther, and F. J. Rauscher III (2000)
Cancer Res. 60, 5803-5814
 |  Abstract »  |  Full Text »

Molecular Heterogeneity and Function of EWS-WT1 Fusion Transcripts in Desmoplastic Small Round Cell Tumors.

J. Liu, M. M. Nau, J. C. Yeh, C. J. Allegra, E. Chu, and J. J. Wright (2000)
Clin. Cancer Res. 6, 3522-3529
 |  Abstract »  |  Full Text »

Immunity to WT1 in the animal model and in patients with acute myeloid leukemia.

A. Gaiger, V. Reese, M. L. Disis, and M. A. Cheever (2000)
Blood 96, 1480-1489
 |  Abstract »  |  Full Text »  |  PDF »

Expression and function of the homeodomain-containing protein Hex in thyroid cells.

L. Pellizzari, A. D'Elia, A. Rustighi, G. Manfioletti, G. Tell, and G. Damante (2000)
Nucleic Acids Res. 28, 2503-2511
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Insulin-Like Growth Factor I Receptor Promoter Activity by Wild-Type and Mutant Versions of the WT1 Tumor Suppressor.

K. Tajinda, J. Carroll, and C. T. Roberts Jr. (1999)
Endocrinology 140, 4713-4724
 |  Abstract »  |  Full Text »

Transcription repression by Xenopus ET and its human ortholog TBX3, a gene involved in ulnar-mammary syndrome.

M.-l. He, L. Wen, C. E. Campbell, J. Y. Wu, and Y. Rao (1999)
PNAS 96, 10212-10217
 |  Abstract »  |  Full Text »  |  PDF »

The Wilms' Tumor Suppressor, WT1, Inhibits 12-O-Tetradecanoylphorbol-13-acetate Activation of the Multidrug Resistance-1 Promoter.

C. McCoy, S. B. McGee, and M. M. Cornwell (1999)
Cell Growth Differ. 10, 377-386
 |  Abstract »  |  Full Text »

CpG oligodeoxynucleotides rescue BKS-2 immature B cell lymphoma from anti-IgM-mediated growth inhibition by up-regulation of egr-1.

S.-S. Han, S.-T. Chung, D. A. Robertson, R. L. Chelvarajan, and S. Bondada (1999)
Int. Immunol. 11, 871-879
 |  Abstract »  |  Full Text »  |  PDF »

Tumor-associated WT1 Missense Mutants Indicate That Transcriptional Activation by WT1 Is Critical for Growth Control.

M. A. English and J. D. Licht (1999)
J. Biol. Chem. 274, 13258-13263
 |  Abstract »  |  Full Text »  |  PDF »

Expression Cloning and Characterization of PREB (Prolactin Regulatory Element Binding), a Novel WD Motif DNA-Binding Protein with a Capacity to Regulate Prolactin Promoter Activity.

M. S. Fliss, P. M. Hinkle, and C. Bancroft (1999)
Mol. Endocrinol. 13, 644-657
 |  Abstract »  |  Full Text »

Induction of Rb-associated Protein (RbAp46) by Wilms' Tumor Suppressor WT1 Mediates Growth Inhibition.

L.-S. Guan, M. Rauchman, and Z.-Y. Wang (1998)
J. Biol. Chem. 273, 27047-27050
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Nuclear MyoD Is Required for Its Rapid Degradation.

A. Song, Q. Wang, M. G. Goebl, and M. A. Harrington (1998)
Mol. Cell. Biol. 18, 4994-4999
 |  Abstract »  |  Full Text »

Tumor Suppressor p53 Can Participate in Transcriptional Induction of the GADD45 Promoter in the Absence of Direct DNA Binding.

Q. Zhan, I-T. Chen, M. J. Antinore, and A. J. Fornace Jr. (1998)
Mol. Cell. Biol. 18, 2768-2778
 |  Abstract »  |  Full Text »

Ciao 1 Is a Novel WD40 Protein That Interacts with the Tumor Suppressor Protein WT1.

R. W. Johnstone, J. Wang, N. Tommerup, H. Vissing, T. Roberts, and Y. Shi (1998)
J. Biol. Chem. 273, 10880-10887
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the Wilms' Tumor Suppressor Gene, WT1, Is Upregulated by Leukemia Inhibitory Factor and Induces Monocytic Differentiation in M1 Leukemic Cells.

S. I. Smith, D. Weil, G. R. Johnson, A. W. Boyd, and C. L. Li (1998)
Blood 91, 764-773
 |  Abstract »  |  Full Text »  |  PDF »

Human EZF, a Kruppel-like Zinc Finger Protein, Is Expressed in Vascular Endothelial Cells and Contains Transcriptional Activation and Repression Domains.

S.-F. Yet, M. M. McA'Nulty, S. C. Folta, H.-W. Yen, M. Yoshizumi, C.-M. Hsieh, M. D. Layne, M. T. Chin, H. Wang, M. A. Perrella, et al. (1998)
J. Biol. Chem. 273, 1026-1031
 |  Abstract »  |  Full Text »  |  PDF »

A Far Upstream Cis-element Is Required for Wilms' Tumor-1 (WT1) Gene Expression in Renal Cell Culture.

H. Scholz, S. A. Bossone, H. T. Cohen, U. Akella, W. M. Strauss, and V. P. Sukhatme (1997)
J. Biol. Chem. 272, 32836-32846
 |  Abstract »  |  Full Text »  |  PDF »

Ionizing Radiation-inducible Apoptosis in the Absence of p53 Linked to Transcription Factor EGR-1.

M. M. Ahmed, S. F. Sells, K. Venkatasubbarao, S. M. Fruitwala, S. Muthukkumar, C. Harp, M. Mohiuddin, and V. M. Rangnekar (1997)
J. Biol. Chem. 272, 33056-33061
 |  Abstract »  |  Full Text »  |  PDF »

The Kruppel-associated Box (KRAB)-Zinc Finger Protein Kid-1 and the Wilms' Tumor Protein WT1, Two Transcriptional Repressor Proteins, Bind to Heteroduplex DNA.

B. Elser, W. Kriz, J. V. Bonventre, C. Englert, and R. Witzgall (1997)
J. Biol. Chem. 272, 27908-27912
 |  Abstract »  |  Full Text »  |  PDF »

Role of Egr-1 Gene Expression in B Cell Receptor-induced Apoptosis in an Immature B Cell Lymphoma.

S. Muthukkumar, S.-S. Han, S. Muthukkumar, V. M. Rangnekar, and S. Bondada (1997)
J. Biol. Chem. 272, 27987-27993
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Osteoclastogenesis by Antisense Oligodeoxynucleotides Specific to Zinc Finger Nuclear Transcription Factors Egr-1 and WT1 in Rat Bone Marrow Culture System.

T. Kukita, A. Kukita, H. Harada, and T. Iijima (1997)
Endocrinology 138, 4384-4389
 |  Abstract »  |  Full Text »  |  PDF »

Early Growth Response-1-dependent Apoptosis Is Mediated by p53.

P. Nair, S. Muthukkumar, S. F. Sells, S.-S. Han, V. P. Sukhatme, and V. M. Rangnekar (1997)
J. Biol. Chem. 272, 20131-20138
 |  Abstract »  |  Full Text »  |  PDF »

The WT1 Protein Is a Negative Regulator of the Normal bcl-2 Allele in t(14;18) Lymphomas.

C. Heckman, E. Mochon, M. Arcinas, and L. M. Boxer (1997)
J. Biol. Chem. 272, 19609-19614
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of Two Human Homologs of the Drosophila single-minded Gene SIM1 on Chromosome 6q and SIM2 on 21q Within the Down Syndrome Chromosomal Region.

R. Chrast, H. S. Scott, H. Chen, J. Kudoh, C. Rossier, S. Minoshima, Y. Wang, N. Shimizu, and S. E. Antonarakis (1997)
Genome Res. 7, 615-624
 |  Abstract »  |  Full Text »  |  PDF »

Sp1 Is a Critical Regulator of the Wilms' tumor-1 Gene.

H. T. Cohen, S. A. Bossone, G. Zhu, G. A. McDonald, and V. P. Sukhatme (1997)
J. Biol. Chem. 272, 2901-2913
 |  Abstract »  |  Full Text »  |  PDF »

Control of germ-band retraction in Drosophila by the zinc-finger protein HINDSIGHT.

M. Yip, M. Lamka, and H. Lipshitz (1997)
Development 124, 2129-2141
 |  Abstract »  |  PDF »

EGR-1 Induction Is Required for Maximal Radiosensitivity in A375-C6 Melanoma Cells.

M. M. Ahmed, K. Venkatasubbarao, S. M. Fruitwala, S. Muthukkumar, D. P. Wood Jr., S. F. Sells, M. Mohiuddin, and V. M. Rangnekar (1996)
J. Biol. Chem. 271, 29231-29237
 |  Abstract »  |  Full Text »  |  PDF »

DNA Binding by Cut Homeodomain Proteins Is Down-modulated by Protein Kinase C.

O. Coqueret, G. Berube, and A. Nepveu (1996)
J. Biol. Chem. 271, 24862-24868
 |  Abstract »  |  Full Text »  |  PDF »

KAP-1, a novel corepressor for the highly conserved KRAB repression domain..

J R Friedman, W J Fredericks, D E Jensen, D W Speicher, X P Huang, E G Neilson, and F J Rauscher (1996)
Genes & Dev. 10, 2067-2078
 |  Abstract »  |  PDF »

The IGF-I Receptor Gene Promoter Is a Molecular Target for the Ewing's Sarcoma-Wilms' Tumor 1Fusion Protein.

E. Karnieli, H. Werner, F. J. Rauscher III, L. E. Benjamin, and D. LeRoith (1996)
J. Biol. Chem. 271, 19304-19309
 |  Abstract »  |  Full Text »  |  PDF »

Egr-1 Activates Basic Fibroblast Growth Factor Transcription. MECHANISTIC IMPLICATIONS FOR ASTROCYTE PROLIFERATION.

E. Biesiada, M. Razandi, and E. R. Levin (1996)
J. Biol. Chem. 271, 18576-18581
 |  Abstract »  |  Full Text »  |  PDF »

Casein Kinase II Associates with Egr-1 and Acts as a Negative Modulator of Its DNA Binding and Transcription Activities in NIH 3T3 Cells.

N. Jain, R. Mahendran, R. Philp, G. R. Guy, Y. H. Tan, and X. Cao (1996)
J. Biol. Chem. 271, 13530-13536
 |  Abstract »  |  Full Text »  |  PDF »

Differential Function of Wilms' Tumor Gene WT1 Splice Isoforms in Transcriptional Regulation.

S. M. Hewitt, G. C. Fraizer, Y.-J. Wu, F. J. Rauscher III, and G. F. Saunders (1996)
J. Biol. Chem. 271, 8588-8592
 |  Abstract »  |  Full Text »  |  PDF »

A Non-AUG Translational Initiation Event Generates Novel WT1 Isoforms.

W. Bruening and J. Pelletier (1996)
J. Biol. Chem. 271, 8646-8654
 |  Abstract »  |  Full Text »  |  PDF »

Human Cytomegalovirus Immediate-Early Protein IE2 Tethers a Transcriptional Repression Domain to p53.

H.-L. Tsai, G.-H. Kou, S.-C. Chen, C.-W. Wu, and Y.-S. Lin (1996)
J. Biol. Chem. 271, 3534-3540
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms Identified in the Transcriptional Control of Epithelial Gene Expression.

G. Hennig, O. Löwrick, W. Birchmeier, and Jür. Behrens (1996)
J. Biol. Chem. 271, 595-602
 |  Abstract »  |  Full Text »  |  PDF »

The Transcriptional Effect of WT1 Is Modulated by Choice of Expression Vector.

J. C. Reddy, S. Hosono, and J. D. Licht (1995)
J. Biol. Chem. 270, 29976-29982
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Functional Domains within the Multifunctional Transcription Factor, YY1.

S. Bushmeyer, K. Park, and M. L. Atchison (1995)
J. Biol. Chem. 270, 30213-30220
 |  Abstract »  |  Full Text »  |  PDF »

Repression of the c-myb Gene by WT1 Protein in T and B Cell Lines.

S. McCann, J. Sullivan, J. Guerra, M. Arcinas, and L. M. Boxer (1995)
J. Biol. Chem. 270, 23785-23789
 |  Abstract »  |  Full Text »  |  PDF »

Isolation and Characterization of a Novel Zinc-finger Protein with Transcriptional Repressor Activity.

A. J. Williams, L. M. Khachigian, T. Shows, and T. Collins (1995)
J. Biol. Chem. 270, 22143-22152
 |  Abstract »  |  Full Text »  |  PDF »

The WT1 gene product stabilizes p53 and inhibits p53-mediated apoptosis..

S Maheswaran, C Englert, P Bennett, G Heinrich, and D A Haber (1995)
Genes & Dev. 9, 2143-2156
 |  Abstract »  |  PDF »

Transcriptional Silencer of the Wilms' Tumor Gene WT1 Contains an Alu Repeat.

S. M. Hewitt, G. C. Fraizer, and G. F. Saunders (1995)
J. Biol. Chem. 270, 17908-17912
 |  Abstract »  |  Full Text »  |  PDF »

Relief of YY1 transcriptional repression by adenovirus E1A is mediated by E1A-associated protein p300..

J S Lee, K M Galvin, R H See, R Eckner, D Livingston, E Moran, and Y Shi (1995)
Genes & Dev. 9, 1188-1198
 |  Abstract »  |  PDF »

WT1-mediated Transcriptional Activation Is Inhibited by Dominant Negative Mutant Proteins.

J. C. Reddy, J. C. Morris, J. Wang, M. A. English, D. A. Haber, Y. Shi, and J. D. Licht (1995)
J. Biol. Chem. 270, 10878-10884
 |  Abstract »  |  Full Text »  |  PDF »

Masking of the CBF1/RBPJ kappa transcriptional repression domain by Epstein-Barr virus EBNA2.

J. Hsieh and S. Hayward (1995)
Science 268, 560-563
 |  Abstract »  |  PDF »

Inserting the Ftz homeodomain into engrailed creates a dominant transcriptional repressor that specifically turns off Ftz target genes in vivo.

A John, S. Smith, and J. Jaynes (1995)
Development 121, 1801-1813
 |  Abstract »  |  PDF »

Repression of Pax-2 by WT1 during normal kidney development.

G Ryan, V Steele-Perkins, J. Morris, F. Rauscher, and G. Dressler (1995)
Development 121, 867-875
 |  Abstract »  |  PDF »

UME6 is a key regulator of nitrogen repression and meiotic development..

R Strich, R T Surosky, C Steber, E Dubois, F Messenguy, and R E Esposito (1994)
Genes & Dev. 8, 796-810
 |  Abstract »  |  PDF »

RNA editing in the Wilms' tumor susceptibility gene, WT1..

P M Sharma, M Bowman, S L Madden, F J Rauscher, and S Sukumar (1994)
Genes & Dev. 8, 720-731
 |  Abstract »  |  PDF »

Adenovirus E1B oncoprotein tethers a transcriptional repression domain to p53..

P R Yew, X Liu, and A J Berk (1994)
Genes & Dev. 8, 190-202
 |  Abstract »  |  PDF »

Novel Oncogenic Mutations in the WT1 Wilms' Tumor Suppressor Gene: A t(11;22) Fuses the Ewing's Sarcoma Gene, EWS1, to WT1 in Desmoplastic Small Round Cell Tumor.

F.J. Rauscher III, L.E. Benjamin, W.J. Fredericks, and J.F. Morris (1994)
Cold Spring Harb Symp Quant Biol 59, 137-146
 |  Abstract »  |  PDF »

Molecular Characterization of QM, a Novel Gene with Properties Consistent with Tumor Suppressor Function.

E. Stanbridge, A. Farmer, A. Mills, T. Loftus, D. Kongkasuriyachai, S. Dowdy, and B. Weissman (1994)
Cold Spring Harb Symp Quant Biol 59, 573-576
 |  Abstract »  |  PDF »

WT1-mediated growth suppression of Wilms tumor cells expressing a WT1 splicing variant.

D. Haber, S Park, S Maheswaran, C Englert, G. Re, D. Hazen-Martin, D. Sens, and A. Garvin (1993)
Science 262, 2057-2059
 |  Abstract »  |  PDF »

Transcriptional repression by the Drosophila even-skipped protein: definition of a minimal repression domain..

K Han and J L Manley (1993)
Genes & Dev. 7, 491-503
 |  Abstract »  |  PDF »

Anti-oncogenic and oncogenic potentials of interferon regulatory factors-1 and -2.

H Harada, M Kitagawa, N Tanaka, H Yamamoto, K Harada, M Ishihara, and T Taniguchi (1993)
Science 259, 971-974
 |  Abstract »

Repression of the insulin-like growth factor II gene by the Wilms tumor suppressor WT1.

I. Drummond, S. Madden, P Rohwer-Nutter, G. Bell, V. Sukhatme, and F. Rauscher 3rd (1992)
Science 257, 674-678
 |  Abstract »  |  PDF »

Modulation of DNA binding specificity by alternative splicing of the Wilms tumor wt1 gene transcript.

W. Bickmore, K Oghene, M. Little, A Seawright, V van Heyningen, and N. Hastie (1992)
Science 257, 235-237
 |  Abstract »  |  PDF »

PAX8, a human paired box gene: isolation and expression in developing thyroid, kidney and Wilms' tumors.

A Poleev, H Fickenscher, S Mundlos, A Winterpacht, B Zabel, A Fidler, P Gruss, and D Plachov (1992)
Development 116, 611-623
 |  Abstract »  |  PDF »

Tumor suppressor genes.

R. Weinberg (1991)
Science 254, 1138-1146
 |  Abstract »  |  PDF »

The Wilms' Tumor Gene Product (WT1) Modulates the Response to 1,25-Dihydroxyvitamin D3 by Induction of the Vitamin D Receptor.

U. Maurer, F. Jehan, C. Englert, G. Hubinger, E. Weidmann, H. F. DeLuca, and L. Bergmann (2001)
J. Biol. Chem. 276, 3727-3732
 |  Abstract »  |  Full Text »  |  PDF »

Ionizing Radiation Down-regulates p53 Protein in Primary Egr-1-/- Mouse Embryonic Fibroblast Cells Causing Enhanced Resistance to Apoptosis.

A. Das, D. Chendil, S. Dey, M. Mohiuddin, M. Mohiuddin, J. Milbrandt, V. M. Rangnekar, and M. M. Ahmed (2001)
J. Biol. Chem. 276, 3279-3286
 |  Abstract »  |  Full Text »  |  PDF »

The Human Sex-determining Gene SRY Is a Direct Target of WT1.

A. Hossain and G. F. Saunders (2001)
J. Biol. Chem. 276, 16817-16823
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A Functional Interaction with CBP Contributes to Transcriptional Activation by the Wilms Tumor Suppressor WT1.

W. Wang, S. B. Lee, R. Palmer, L. W. Ellisen, and D. A. Haber (2001)
J. Biol. Chem. 276, 16810-16816
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The Zinc Finger Domain of Tzfp Binds to the tbs Motif Located at the Upstream Flanking Region of the Aie1 (aurora-C) Kinase Gene.

C.-J. C. Tang, C.-K. Chuang, H.-M. Hu, and T. K. Tang (2001)
J. Biol. Chem. 276, 19631-19639
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Molecular genetics of chromosome translocations involving EWS and related family members.

J. KIM and J. PELLETIER (1999)
Physiol Genomics 1, 127-138
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