Science 20 September 1991: Vol. 253. no. 5026, pp. 1417 - 1420 DOI: 10.1126/science.1910207

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Articles

MHC Drives TCR Repertoire Shaping, but not Maturation, in Recent Thymic Emigrants.

E. G. Houston Jr. and P. J. Fink (2009)
J. Immunol. 183, 7244-7249
 |  Abstract »  |  Full Text »  |  PDF »

The Activation Threshold of CD4+ T Cells Is Defined by TCR/Peptide-MHC Class II Interactions in the Thymic Medulla.

T. L. Stephen, A. Tikhonova, J. M. Riberdy, and T. M. Laufer (2009)
J. Immunol. 183, 5554-5562
 |  Abstract »  |  Full Text »  |  PDF »

Functionally Mature CD4 and CD8 TCR{alpha}{beta} Cells Are Generated in OP9-DL1 Cultures from Human CD34+ Hematopoietic Cells.

S. Van Coppernolle, G. Verstichel, F. Timmermans, I. Velghe, D. Vermijlen, M. De Smedt, G. Leclercq, J. Plum, T. Taghon, B. Vandekerckhove, et al. (2009)
J. Immunol. 183, 4859-4870
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: CD4-Independent Development of Functional FoxP3+ Regulatory T Cells.

C. Blache, S. Adriouch, S. Calbo, L. Drouot, S. Dulauroy, C. Arnoult, S. Le Corre, A. Six, M. Seman, and O. Boyer (2009)
J. Immunol. 183, 4182-4186
 |  Abstract »  |  Full Text »  |  PDF »

Alveolar Macrophages and Lung Dendritic Cells Sense RNA and Drive Mucosal IgA Responses.

J. Bessa, A. Jegerlehner, H. J. Hinton, P. Pumpens, P. Saudan, P. Schneider, and M. F. Bachmann (2009)
J. Immunol. 183, 3788-3799
 |  Abstract »  |  Full Text »  |  PDF »

Expansion of peripheral naturally occurring T regulatory cells by Fms-like tyrosine kinase 3 ligand treatment.

L. K. Swee, N. Bosco, B. Malissen, R. Ceredig, and A. Rolink (2009)
Blood 113, 6277-6287
 |  Abstract »  |  Full Text »  |  PDF »

Colitis immunoregulation by CD8+ T cell requires T cell cytotoxicity and B cell peptide antigen presentation.

M. McPherson, B. Wei, O. Turovskaya, D. Fujiwara, S. Brewer, and J. Braun (2008)
Am J Physiol Gastrointest Liver Physiol 295, G485-G492
 |  Abstract »  |  Full Text »  |  PDF »

Alloreactive CD8 T Cell Tolerance Requires Recipient B Cells, Dendritic Cells, and MHC Class II.

T. Fehr, F. Haspot, J. Mollov, M. Chittenden, T. Hogan, and M. Sykes (2008)
J. Immunol. 181, 165-173
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Functions of C2D macrophage cells after adoptive transfer.

B. E. Potts and S. K. Chapes (2008)
J. Leukoc. Biol. 83, 602-609
 |  Abstract »  |  Full Text »  |  PDF »

Effector memory CD4+ T cells mediate graft-versus-leukemia without inducing graft-versus-host disease.

H. Zheng, C. Matte-Martone, H. Li, B. E. Anderson, S. Venketesan, H. Sheng Tan, D. Jain, J. McNiff, and W. D. Shlomchik (2008)
Blood 111, 2476-2484
 |  Abstract »  |  Full Text »  |  PDF »

Repression of the Transcription Factor Th-POK by Runx Complexes in Cytotoxic T Cell Development.

R. Setoguchi, M. Tachibana, Y. Naoe, S. Muroi, K. Akiyama, C. Tezuka, T. Okuda, and I. Taniuchi (2008)
Science 319, 822-825
 |  Abstract »  |  Full Text »  |  PDF »

Differentiation of C2D Macrophage Cells after Adoptive Transfer.

B. E. Potts, M. L. Hart, L. L. Snyder, D. Boyle, D. A. Mosier, and S. K. Chapes (2008)
Clin. Vaccine Immunol. 15, 243-252
 |  Abstract »  |  Full Text »  |  PDF »

CCR7 Expression in Developing Thymocytes Is Linked to the CD4 versus CD8 Lineage Decision.

X. Yin, E. Ladi, S. W. Chan, O. Li, N. Killeen, D. J. Kappes, and E. A. Robey (2007)
J. Immunol. 179, 7358-7364
 |  Abstract »  |  Full Text »  |  PDF »

Natural Killer Cells and CD4+ T-Cells Modulate Collateral Artery Development.

V. van Weel, R.E.M. Toes, L. Seghers, M.M.L. Deckers, M.R. de Vries, P.H. Eilers, J. Sipkens, A. Schepers, D. Eefting, V.W.M. van Hinsbergh, et al. (2007)
Arterioscler Thromb Vasc Biol 27, 2310-2318
 |  Abstract »  |  Full Text »  |  PDF »

Antigen, in the Presence of TGF-beta, Induces Up-Regulation of FoxP3gfp+ in CD4+ TCR Transgenic T Cells That Mediate Linked Suppression of CD8+ T Cell Responses.

J. A. Kapp, K. Honjo, L. M. Kapp, K. Goldsmith, and R. P. Bucy (2007)
J. Immunol. 179, 2105-2114
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Antigen Stability Affects DNA Vaccine Immunogenicity.

A. D. Bins, M. C. Wolkers, M. D. van den Boom, J. B. A. G. Haanen, and T. N. M. Schumacher (2007)
J. Immunol. 179, 2126-2133
 |  Abstract »  |  Full Text »  |  PDF »

OX40 Costimulation Promotes Persistence of Cytomegalovirus-Specific CD8 T Cells: A CD4-Dependent Mechanism.

I. R. Humphreys, A. Loewendorf, C. de Trez, K. Schneider, C. A. Benedict, M. W. Munks, C. F. Ware, and M. Croft (2007)
J. Immunol. 179, 2195-2202
 |  Abstract »  |  Full Text »  |  PDF »

CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.

Y. Kuwano, C. M. Prazma, N. Yazawa, R. Watanabe, N. Ishiura, A. Kumanogoh, H. Okochi, K. Tamaki, M. Fujimoto, and T. F. Tedder (2007)
Int. Immunol. 19, 977-992
 |  Abstract »  |  Full Text »  |  PDF »

The Antiviral CD8+ T Cell Response Is Differentially Dependent on CD4+ T Cell Help Over the Course of Persistent Infection.

C. C. Kemball, C. D. Pack, H. M. Guay, Z.-N. Li, D. A. Steinhauer, E. Szomolanyi-Tsuda, and A. E. Lukacher (2007)
J. Immunol. 179, 1113-1121
 |  Abstract »  |  Full Text »  |  PDF »

Regulatory function of CD4+CD25+ T cells from Class II MHC-deficient mice in contact hypersensitivity responses.

D. D. Kish, A. V. Gorbachev, and R. L. Fairchild (2007)
J. Leukoc. Biol. 82, 85-92
 |  Abstract »  |  Full Text »  |  PDF »

Cytomegalovirus exploits IL-10-mediated immune regulation in the salivary glands.

I. R. Humphreys, C. de Trez, A. Kinkade, C. A. Benedict, M. Croft, and C. F. Ware (2007)
J. Exp. Med. 204, 1217-1225
 |  Abstract »  |  Full Text »  |  PDF »

Live Attenuated Streptococcus pneumoniae Strains Induce Serotype-Independent Mucosal and Systemic Protection in Mice.

A. M. Roche, S. J. King, and J. N. Weiser (2007)
Infect. Immun. 75, 2469-2475
 |  Abstract »  |  Full Text »  |  PDF »

Antiviral CD4+ memory T cells are IL-15 dependent.

J. F. Purton, J. T. Tan, M. P. Rubinstein, D. M. Kim, J. Sprent, and C. D. Surh (2007)
J. Exp. Med. 204, 951-961
 |  Abstract »  |  Full Text »  |  PDF »

Donor-derived thymic-dependent T cells cause chronic graft-versus-host disease.

Y. Sakoda, D. Hashimoto, S. Asakura, K. Takeuchi, M. Harada, M. Tanimoto, and T. Teshima (2007)
Blood 109, 1756-1764
 |  Abstract »  |  Full Text »  |  PDF »

CD4+ T-Cell Responses Are Required for Clearance of West Nile Virus from the Central Nervous System.

E. M. Sitati and M. S. Diamond (2006)
J. Virol. 80, 12060-12069
 |  Abstract »  |  Full Text »  |  PDF »

Functional Adaptive CD4 Foxp3 T Cells Develop in MHC Class II-Deficient Mice.

P. Bochtler, C. Wahl, R. Schirmbeck, and J. Reimann (2006)
J. Immunol. 177, 8307-8314
 |  Abstract »  |  Full Text »  |  PDF »

Coreceptor Signal Strength Regulates Positive Selection but Does Not Determine CD4/CD8 Lineage Choice in a Physiologic In Vivo Model.

B. Erman, A. S. Alag, O. Dahle, F. van Laethem, S. D. Sarafova, T. I. Guinter, S. O. Sharrow, A. Grinberg, P. E. Love, and A. Singer (2006)
J. Immunol. 177, 6613-6625
 |  Abstract »  |  Full Text »  |  PDF »

A Pathogenic Role for CD8+ T Cells in a Spontaneous Model of Demyelinating Disease.

M. Brisebois, S. P. Zehntner, J. Estrada, T. Owens, and S. Fournier (2006)
J. Immunol. 177, 2403-2411
 |  Abstract »  |  Full Text »  |  PDF »

Gastric mucosal hyperplasia via upregulation of gastrin induced by persistent activation of gastric innate immunity in major histocompatibility complex class II deficient mice.

T Fukui, A Nishio, K Okazaki, N Uza, S Ueno, M Kido, S Inoue, H Kitamura, K Kiriya, S Ohashi, et al. (2006)
Gut 55, 607-615
 |  Abstract »  |  Full Text »  |  PDF »

H2-O Expression in Primary Dendritic Cells.

X. Chen, L. M. Reed-Loisel, L. Karlsson, and P. E. Jensen (2006)
J. Immunol. 176, 3548-3556
 |  Abstract »  |  Full Text »  |  PDF »

Developmental Alterations in Thymocyte Sensitivity Are Actively Regulated by MHC Class II Expression in the Thymic Medulla.

S. C. Eck, P. Zhu, M. Pepper, S. J. Bensinger, B. D. Freedman, and T. M. Laufer (2006)
J. Immunol. 176, 2229-2237
 |  Abstract »  |  Full Text »  |  PDF »

Purified hematopoietic stem cell engraftment of rare niches corrects severe lymphoid deficiencies without host conditioning.

D. Bhattacharya, D. J. Rossi, D. Bryder, and I. L. Weissman (2006)
J. Exp. Med. 203, 73-85
 |  Abstract »  |  Full Text »  |  PDF »

Molecular, Cellular, and Antigen Requirements for Development of Age-Associated T Cell Clonal Expansions In Vivo.

I. Messaoudi, J. Warner, D. Nikolich-Zugich, M. Fischer, and J. Nikolich-Zugich (2006)
J. Immunol. 176, 301-308
 |  Abstract »  |  Full Text »  |  PDF »

CD1d-Independent Developmental Acquisition of Prompt IL-4 Gene Inducibility in Thymus CD161(NK1)-CD44lowCD4+CD8- T Cells Is Associated with Complementarity Determining Region 3-Diverse and Biased V{beta}2/V{beta}7/V{beta}8/V{alpha}3.2 T Cell Receptor Usage.

Y.-T. Chen and J. T. Kung (2005)
J. Immunol. 175, 6537-6550
 |  Abstract »  |  Full Text »  |  PDF »

Host and Bacterial Factors Contributing to the Clearance of Colonization by Streptococcus pneumoniae in a Murine Model.

A. M. C. van Rossum, E. S. Lysenko, and J. N. Weiser (2005)
Infect. Immun. 73, 7718-7726
 |  Abstract »  |  Full Text »  |  PDF »

A {beta}-lactamase with reduced immunogenicity for the targeted delivery of chemotherapeutics using antibody-directed enzyme prodrug therapy.

F. A. Harding, A. D. Liu, M. Stickler, O. J. Razo, R. Chin, N. Faravashi, W. Viola, T. Graycar, V. P. Yeung, W. Aehle, et al. (2005)
Mol. Cancer Ther. 4, 1791-1800
 |  Abstract »  |  Full Text »  |  PDF »

MHC-Mismatched Islet Allografts Are Vulnerable to Autoimmune Recognition In Vivo.

T. M. Kupfer, M. L. Crawford, K. Pham, and R. G. Gill (2005)
J. Immunol. 175, 2309-2316
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic Cells Cross-Present Exogenous Fungal Antigens to Stimulate a Protective CD8 T Cell Response in Infection by Histoplasma capsulatum.

J.-S. Lin, C.-W. Yang, D.-W. Wang, and B. A. Wu-Hsieh (2005)
J. Immunol. 174, 6282-6291
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Impaired Antitumor Immunity by Fusion of MHC Class II-Deficient Dendritic Cells with Tumor Cells.

Y. Tanaka, S. Koido, M. Ohana, C. Liu, and J. Gong (2005)
J. Immunol. 174, 1274-1280
 |  Abstract »  |  Full Text »  |  PDF »

Induction of CD70 on Dendritic Cells through CD40 or TLR Stimulation Contributes to the Development of CD8+ T Cell Responses in the Absence of CD4+ T Cells.

T. N. J. Bullock and H. Yagita (2005)
J. Immunol. 174, 710-717
 |  Abstract »  |  Full Text »  |  PDF »

Mechanism of Action of Donor-Specific Transfusion in Inducing Tolerance: Role of Donor MHC Molecules, Donor Co-stimulatory Molecules, and Indirect Antigen Presentation.

K. Kishimoto, X. Yuan, H. Auchincloss Jr., A. H. Sharpe, D. A. Mandelbrot, and M. H. Sayegh (2004)
J. Am. Soc. Nephrol. 15, 2423-2428
 |  Abstract »  |  Full Text »  |  PDF »

Dissecting MHC Class II Export, B Cell Maturation, and DM Stability Defects in Invariant Chain Mutant Mice.

C. H. Koonce and E. K. Bikoff (2004)
J. Immunol. 173, 3271-3280
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the B7.1 Costimulatory Molecule on Pancreatic {beta} Cells Abrogates the Requirement for CD4 T Cells in the Development of Type 1 Diabetes.

E. Havari, A. M. Lennon-Dumenil, L. Klein, D. Neely, J. A. Taylor, M. F. McInerney, K. W. Wucherpfennig, and M. A. Lipes (2004)
J. Immunol. 173, 787-796
 |  Abstract »  |  Full Text »  |  PDF »

MHC class II-independent and -dependent T cell expansion and B cell hyperactivity in vivo in mice deficient in CD152 (CTLA-4).

W. Stohl, D. Xu, K. S. Kim, C. S. David, and J. P. Allison (2004)
Int. Immunol. 16, 895-904
 |  Abstract »  |  Full Text »  |  PDF »

Defined {alpha}{beta} T Cell Receptors with Distinct Ligand Specificities Do Not Require Those Ligands to Signal Double Negative Thymocyte Differentiation.

B. Erman, T. I. Guinter, and A. Singer (2004)
J. Exp. Med. 199, 1719-1724
 |  Abstract »  |  Full Text »  |  PDF »

Host Dendritic Cells Alone Are Sufficient to Initiate Acute Graft-versus-Host Disease.

U. A. Duffner, Y. Maeda, K. R. Cooke, P. Reddy, R. Ordemann, C. Liu, J. L. M. Ferrara, and T. Teshima (2004)
J. Immunol. 172, 7393-7398
 |  Abstract »  |  Full Text »  |  PDF »

Development of Antigen-Specific CD8+ CTL in MHC Class I-Deficient Mice through CD4 to CD8 Conversion.

Y. Tanaka, S. Koido, J. Xia, M. Ohana, C. Liu, G. M. Cote, D. B. Sawyer, S. Calderwood, and J. Gong (2004)
J. Immunol. 172, 7848-7858
 |  Abstract »  |  Full Text »  |  PDF »

Graft-versus-leukemia in a retrovirally induced murine CML model: mechanisms of T-cell killing.

C. C. Matte, J. Cormier, B. E. Anderson, I. Athanasiadis, J. Liu, S. G. Emerson, W. Pear, and W. D. Shlomchik (2004)
Blood 103, 4353-4361
 |  Abstract »  |  Full Text »  |  PDF »

Essential role of MHC II-independent CD4+ T cells, IL-4 and STAT6 in contact hypersensitivity induced by fluorescein isothiocyanate in the mouse.

K. Takeshita, T. Yamasaki, S. Akira, F. Gantner, and K. B. Bacon (2004)
Int. Immunol. 16, 685-695
 |  Abstract »  |  Full Text »  |  PDF »

Highly attenuated smallpox vaccine protects mice with and without immune deficiencies against pathogenic vaccinia virus challenge.

L. S. Wyatt, P. L. Earl, L. A. Eller, and B. Moss (2004)
PNAS 101, 4590-4595
 |  Abstract »  |  Full Text »  |  PDF »

The CD8 Population in CD4-deficient Mice Is Heavily Contaminated with MHC Class II-restricted T Cells.

A. J. Tyznik, J. C. Sun, and M. J. Bevan (2004)
J. Exp. Med. 199, 559-565
 |  Abstract »  |  Full Text »  |  PDF »

A Spontaneous Model for Autoimmune Myocarditis Using the Human MHC Molecule HLA-DQ8.

J. A. Taylor, E. Havari, M. F. McInerney, R. Bronson, K. W. Wucherpfennig, and M. A. Lipes (2004)
J. Immunol. 172, 2651-2658
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxic-T-Lymphocyte Human Papillomavirus Type 16 E5 Peptide with CpG-Oligodeoxynucleotide Can Eliminate Tumor Growth in C57BL/6 Mice.

Y.-F. Chen, C.-W. Lin, Y.-P. Tsao, and S.-L. Chen (2004)
J. Virol. 78, 1333-1343
 |  Abstract »  |  Full Text »  |  PDF »

Delayed Clearance of Ehrlichia chaffeensis Infection in CD4+ T-Cell Knockout Mice{dagger}.

R. R. Ganta, C. Cheng, M. J. Wilkerson, and S. K. Chapes (2004)
Infect. Immun. 72, 159-167
 |  Abstract »  |  Full Text »  |  PDF »

CD8{alpha}+ and CD11b+ Dendritic Cell-Restricted MHC Class II Controls Th1 CD4+ T Cell Immunity.

M. P. Lemos, L. Fan, D. Lo, and T. M. Laufer (2003)
J. Immunol. 171, 5077-5084
 |  Abstract »  |  Full Text »  |  PDF »

Functional Genomic Analysis of Remyelination Reveals Importance of Inflammation in Oligodendrocyte Regeneration.

H. A. Arnett, Y. Wang, G. K. Matsushima, K. Suzuki, and J. P.-Y. Ting (2003)
J. Neurosci. 23, 9824-9832
 |  Abstract »  |  Full Text »  |  PDF »

An Early CD4+ T Cell-dependent Immunoglobulin A Response to Influenza Infection in the Absence of Key Cognate T-B Interactions.

M. Y. Sangster, J. M. Riberdy, M. Gonzalez, D. J. Topham, N. Baumgarth, and P. C. Doherty (2003)
J. Exp. Med. 198, 1011-1021
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla.

M. Nasreen, T. Ueno, F. Saito, and Y. Takahama (2003)
J. Immunol. 171, 3394-3400
 |  Abstract »  |  Full Text »  |  PDF »

Negative selection imparts peptide specificity to the mature T cell repertoire.

E. S. Huseby, F. Crawford, J. White, J. Kappler, and P. Marrack (2003)
PNAS 100, 11565-11570
 |  Abstract »  |  Full Text »  |  PDF »

T Cells Cause Acute Immunopathology and Are Required for Long-Term Survival in Mouse Adenovirus Type 1-Induced Encephalomyelitis.

M. L. Moore, C. C. Brown, and K. R. Spindler (2003)
J. Virol. 77, 10060-10070
 |  Abstract »  |  Full Text »  |  PDF »

Impaired thymic negative selection causes autoimmune graft-versus-host disease.

T. Teshima, P. Reddy, C. Liu, D. Williams, K. R. Cooke, and J. L. M. Ferrara (2003)
Blood 102, 429-435
 |  Abstract »  |  Full Text »  |  PDF »

Unraveling a Revealing Paradox: Why Major Histocompatibility Complex I-signaled Thymocytes "Paradoxically" Appear as CD4+8lo Transitional Cells During Positive Selection of CD8+ T Cells.

R. Bosselut, T. I. Guinter, S. O. Sharrow, and A. Singer (2003)
J. Exp. Med. 197, 1709-1719
 |  Abstract »  |  Full Text »  |  PDF »

Protection and compensation in the influenza virus-specific CD8+ T cell response.

R. J. Webby, S. Andreansky, J. Stambas, J. E. Rehg, R. G. Webster, P. C. Doherty, and S. J. Turner (2003)
PNAS 100, 7235-7240
 |  Abstract »  |  Full Text »  |  PDF »

Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells: Implications for Vaccine Development in Immune-deficient Hosts.

M. Wuthrich, H. I. Filutowicz, T. Warner, G. S. Deepe Jr., and B. S. Klein (2003)
J. Exp. Med. 197, 1405-1416
 |  Abstract »  |  Full Text »  |  PDF »

The Degree of Phylogenetic Disparity of Islet Grafts Dictates the Reliance on Indirect CD4 T-Cell Antigen Recognition for Rejection.

G. R. Rayat, Z. A. Johnson, J. N. Beilke, G. S. Korbutt, R. V. Rajotte, and R. G. Gill (2003)
Diabetes 52, 1433-1440
 |  Abstract »  |  Full Text »  |  PDF »

Promoter IV of the class II transactivator gene is essential for positive selection of CD4+ T cells.

J.-M. Waldburger, S. Rossi, G. A. Hollander, H.-R. Rodewald, W. Reith, and H. Acha-Orbea (2003)
Blood 101, 3550-3559
 |  Abstract »  |  Full Text »  |  PDF »

Hierarchical Contributions of Allorecognition Pathways in Chronic Lung Rejection.

W. Chalermskulrat, I. P. Neuringer, W. J. Brickey, N. J. Felix, S. H. Randell, J. P. Ting, and R. M. Aris (2003)
Am. J. Respir. Crit. Care Med. 167, 999-1007
 |  Abstract »  |  Full Text »  |  PDF »

Antigen presentation by keratinocytes directs autoimmune skin disease.

L. Fan, B. W. Busser, T. Q. Lifsted, D. Lo, and T. M. Laufer (2003)
PNAS 100, 3386-3391
 |  Abstract »  |  Full Text »  |  PDF »

Primed Peritoneal B Lymphocytes Are Sufficient To Transfer Protection against Brugia pahangi Infection in Mice.

N. Paciorkowski, L. D. Shultz, and T. V. Rajan (2003)
Infect. Immun. 71, 1370-1378
 |  Abstract »  |  Full Text »  |  PDF »

Toll-Like Receptor 4-Positive Macrophages Protect Mice from Pasteurella pneumotropica-Induced Pneumonia.

M. L. Hart, D. A. Mosier, and S. K. Chapes (2003)
Infect. Immun. 71, 663-670
 |  Abstract »  |  Full Text »  |  PDF »

Murine CD4 T Cells Selected in a Highly Disparate Xenogeneic Porcine Thymus Graft Do Not Show Rapid Decay in the Absence of Selecting MHC in the Periphery.

J.-I. Rodriguez-Barbosa, Y. Zhao, G. Zhao, A. Ezquerra, and M. Sykes (2002)
J. Immunol. 169, 6697-6710
 |  Abstract »  |  Full Text »  |  PDF »

Tumor suppression induced by intratumor administration of adenovirus vector expressing NK4, a 4-kringle antagonist of hepatocyte growth factor, and naive dendritic cells.

T. Kikuchi, M. Maemondo, K. Narumi, K. Matsumoto, T. Nakamura, and T. Nukiwa (2002)
Blood 100, 3950-3959
 |  Abstract »  |  Full Text »  |  PDF »

Compromised Influenza Virus-Specific CD8+-T-Cell Memory in CD4+-T-Cell-Deficient Mice.

G. T. Belz, D. Wodarz, G. Diaz, M. A. Nowak, and P. C. Doherty (2002)
J. Virol. 76, 12388-12393
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of thymic epithelium by keratinocyte growth factor.

M. Erickson, S. Morkowski, S. Lehar, G. Gillard, C. Beers, J. Dooley, J. S. Rubin, A. Rudensky, and A. G. Farr (2002)
Blood 100, 3269-3278
 |  Abstract »  |  Full Text »  |  PDF »

Mice Deficient in Perforin, CD4+ T Cells, or CD28-Mediated Signaling Maintain the Typical Immunodominance Hierarchies of CD8+ T-Cell Responses to Influenza Virus.

W. Chen, J. R. Bennink, P. A. Morton, and J. W. Yewdell (2002)
J. Virol. 76, 10332-10337
 |  Abstract »  |  Full Text »  |  PDF »

Inhibitory Effects of Cytomegalovirus Proteins US2 and US11 Point to Contributions from Direct Priming and Cross-Priming in Induction of Vaccinia Virus-Specific CD8+ T Cells.

S. Basta, W. Chen, J. R. Bennink, and J. W. Yewdell (2002)
J. Immunol. 168, 5403-5408
 |  Abstract »  |  Full Text »  |  PDF »

Optimizing the Efficacy of Epitope-Directed DNA Vaccination.

M. C. Wolkers, M. Toebes, M. Okabe, J. B. A. G. Haanen, and T. N. M. Schumacher (2002)
J. Immunol. 168, 4998-5004
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant Expression of Fas Ligand in Mice Deficient for the MHC Class II Transactivator.

T. S. Gourley, D. R. Patel, K. Nickerson, S.-C. Hong, and C.-H. Chang (2002)
J. Immunol. 168, 4414-4419
 |  Abstract »  |  Full Text »  |  PDF »

Reduced Functional Capacity of CD8+ T Cells Expanded by Post-Exposure Vaccination of {gamma}-Herpesvirus-Infected CD4-Deficient Mice.

H. Liu, S. Andreansky, G. Diaz, T. Hogg, and P. C. Doherty (2002)
J. Immunol. 168, 3477-3483
 |  Abstract »  |  Full Text »  |  PDF »

Persistent Ehrlichia chaffeensis Infection Occurs in the Absence of Functional Major Histocompatibility Complex Class II Genes.

R. R. Ganta, M. J. Wilkerson, C. Cheng, A. M. Rokey, and S. K. Chapes (2002)
Infect. Immun. 70, 380-388
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Recipient MHC Class II Expression Is Required to Achieve Long-Term Survival of Murine Cardiac Allografts After Costimulatory Blockade.

A. Yamada, A. Chandraker, T. M. Laufer, A. J. Gerth, M. H. Sayegh, and H. Auchincloss Jr. (2001)
J. Immunol. 167, 5522-5526
 |  Abstract »  |  Full Text »  |  PDF »

Modulation of Blood Fluke Development in the Liver by Hepatic CD4+ Lymphocytes.

S. J. Davies, J. L. Grogan, R. B. Blank, K. C. Lim, R. M. Locksley, and J. H. McKerrow (2001)
Science 294, 1358-1361
 |  Abstract »  |  Full Text »  |  PDF »

Acute Rejection of Orthotopic Corneal Xenografts in Mice Depends on CD4+ T Cells and Self-Antigen-Presenting Cells.

K. Tanaka, K.-h. Sonoda, and J. W. Streilein (2001)
Invest. Ophthalmol. Vis. Sci. 42, 2878-2884
 |  Abstract »  |  Full Text »  |  PDF »

Redundancy of Direct Priming and Cross-Priming in Tumor-Specific CD8+ T Cell Responses.

M. C. Wolkers, G. Stoetter, F. A. Vyth-Dreese, and T. N. M. Schumacher (2001)
J. Immunol. 167, 3577-3584
 |  Abstract »  |  Full Text »  |  PDF »

Genome sequence of an industrial microorganism Streptomyces avermitilis: Deducing the ability of producing secondary metabolites.

S. Omura, H. Ikeda, J. Ishikawa, A. Hanamoto, C. Takahashi, M. Shinose, Y. Takahashi, H. Horikawa, H. Nakazawa, T. Osonoe, et al. (2001)
PNAS
 |  Abstract »  |  Full Text »  |  PDF »

""What"" and ""where"" in the human auditory system.

C. Alain, S. R. Arnott, S. Hevenor, S. Graham, and C. L. Grady (2001)
PNAS
 |  Abstract »  |  Full Text »  |  PDF »

Major Histocompatibility Complex Class II-Positive Cortical Epithelium Mediates the Selection of Cd4+25+ Immunoregulatory T Cells.

S. J. Bensinger, A. Bandeira, M. S. Jordan, A. J. Caton, and T. M. Laufer (2001)
J. Exp. Med. 194, 427-438
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Paths for Activation of Naive CD8+ T Cells: CD4-Independent Help.

B. Wang, C. C. Norbury, R. Greenwood, J. R. Bennink, J. W. Yewdell, and J. A. Frelinger (2001)
J. Immunol. 167, 1283-1289
 |  Abstract »  |  Full Text »  |  PDF »

Neural change in Trichinella-infected mice is MHC II independent and involves M-CSF-derived macrophages.

F. Galeazzi, P. Lovato, P. A. Blennerhassett, E. M. Haapala, B. A. Vallance, and S. M. Collins (2001)
Am J Physiol Gastrointest Liver Physiol 281, G151-G158
 |  Abstract »  |  Full Text »  |  PDF »

Virus-Specific and Bystander CD8+ T-Cell Proliferation in the Acute and Persistent Phases of a Gammaherpesvirus Infection.

G. T. Belz and P. C. Doherty (2001)
J. Virol. 75, 4435-4438
 |  Abstract »  |  Full Text »

Negative Regulation of CD4 Gene Expression by a HES-1-c-Myb Complex.

R. D. Allen III, H. K. Kim, S. D. Sarafova, and G. Siu (2001)
Mol. Cell. Biol. 21, 3071-3082
 |  Abstract »  |  Full Text »

Autonomous Maturation of {alpha}/{beta} T Lineage Cells in the Absence of Cooh-Terminal Src Kinase (Csk).

C. Schmedt and A. Tarakhovsky (2001)
J. Exp. Med. 193, 815-826
 |  Abstract »  |  Full Text »  |  PDF »

MHCII, Tlr4 and Nramp1 genes control host pulmonary resistance against the opportunistic bacterium Pasteurella pneumotropica.

S. K. Chapes, D. A. Mosier, A. D. Wright, and M. L. Hart (2001)
J. Leukoc. Biol. 69, 381-386
 |  Abstract »  |  Full Text »

Organ-Specific Regulation of the CD8 T Cell Response to Listeria monocytogenes Infection.

C. Pope, S.-K. Kim, A. Marzo, K. Williams, J. Jiang, H. Shen, and L. Lefrancois (2001)
J. Immunol. 166, 3402-3409
 |  Abstract »  |  Full Text »  |  PDF »

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