Science 14 June 1991: Vol. 252. no. 5012, pp. 1560 - 1562 DOI: 10.1126/science.1840699

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Articles

Supramolecular Assemblies and Localized Regulation of Voltage-Gated Ion Channels.

S. Dai, D. D. Hall, and J. W. Hell (2009)
Physiol Rev 89, 411-452
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Profile of Barry Ganetzky.

M. Marino (2007)
PNAS 104, 11515-11517
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Genetic Modifications of Seizure Susceptibility and Expression by Altered Excitability in Drosophila Na+ and K+ Channel Mutants.

J. Lee and C.-F. Wu (2006)
J Neurophysiol 96, 2465-2478
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Silencing the Activity and Proliferative Properties of the Human EagI Potassium Channel by RNA Interference.

C. Weber, F. M. de Queiroz, B. R. Downie, A. Suckow, W. Stuhmer, and L. A. Pardo (2006)
J. Biol. Chem. 281, 13030-13037
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In Vivo Analysis of a Gain-of-Function Mutation in the Drosophila eag-Encoded K+ Channel.

R. J. G. Cardnell, D. E. Dalle Nogare, B. Ganetzky, and M. Stern (2006)
Genetics 172, 2351-2358
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Optical detection of rate-determining ion-modulated conformational changes of the ether-a-go-go K+ channel voltage sensor.

J. P. A. Bannister, B. Chanda, F. Bezanilla, and D. M. Papazian (2005)
PNAS 102, 18718-18723
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A Drosophila KCNQ Channel Essential for Early Embryonic Development.

H. Wen, T. M. Weiger, T. S. Ferguson, M. Shahidullah, S. S. Scott, and I. B. Levitan (2005)
J. Neurosci. 25, 10147-10156
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Molecular Physiology of Cardiac Repolarization.

J. M. Nerbonne and R. S. Kass (2005)
Physiol Rev 85, 1205-1253
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Camguk/CASK Enhances Ether-A-Go-Go Potassium Current by a Phosphorylation-Dependent Mechanism.

D. D. Marble, A. P. Hegle, E. D. Snyder II, S. Dimitratos, P. J. Bryant, and G. F. Wilson (2005)
J. Neurosci. 25, 4898-4907
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The VGL-Chanome: A Protein Superfamily Specialized for Electrical Signaling and Ionic Homeostasis.

F. H. Yu and W. A. Catterall (2004)
Sci. STKE 2004, re15
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Voltage-Gated Potassium Channels in Cell Proliferation.

L. A. Pardo (2004)
Physiology 19, 285-292
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Mechanism of Block of hEag1 K+ Channels by Imipramine and Astemizole.

R. E. Garcia-Ferreiro, D. Kerschensteiner, F. Major, F. Monje, W. Stuhmer, and L. A. Pardo (2004)
J. Gen. Physiol. 124, 301-317
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Neuronal Activity and Adenylyl Cyclase in Environment-Dependent Plasticity of Axonal Outgrowth in Drosophila.

Y. Zhong and C.-F. Wu (2004)
J. Neurosci. 24, 1439-1445
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Distribution and functional properties of human KCNH8 (Elk1) potassium channels.

A. Zou, Z. Lin, M. Humble, C. D. Creech, P. K. Wagoner, D. Krafte, T. J. Jegla, and A. D. Wickenden (2003)
Am J Physiol Cell Physiol 285, C1356-C1366
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of a Novel Gastropod Toxin (6-Bromo-2-mercaptotryptamine) That Inhibits Shaker K Channel Activity.

W. P. Kelley, A. M. Wolters, J. T. Sack, R. A. Jockusch, J. C. Jurchen, E. R. Williams, J. V. Sweedler, and W. F. Gilly (2003)
J. Biol. Chem. 278, 34934-34942
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Molecular Dissection of the Contribution of Negatively and Positively Charged Residues in S2, S3, and S4 to the Final Membrane Topology of the Voltage Sensor in the K+ Channel, KAT1.

Y. Sato, M. Sakaguchi, S. Goshima, T. Nakamura, and N. Uozumi (2003)
J. Biol. Chem. 278, 13227-13234
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Caenorhabditis elegans UNC-103 ERG-Like Potassium Channel Regulates Contractile Behaviors of Sex Muscles in Males before and during Mating.

L. R. Garcia and P. W. Sternberg (2003)
J. Neurosci. 23, 2696-2705
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Cyclic Nucleotide-Gated Ion Channels.

U. B. Kaupp and R. Seifert (2002)
Physiol Rev 82, 769-824
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Calcium/Calmodulin-dependent Protein Kinase II Phosphorylates and Regulates the Drosophila Eag Potassium Channel.

Z. Wang, G. F. Wilson, and L. C. Griffith (2002)
J. Biol. Chem. 277, 24022-24029
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Properties of the Drosophila inebriated-Encoded Neurotransmitter Transporter.

Y. Huang and M. Stern (2002)
J. Neurosci. 22, 1698-1708
 |  Abstract »  |  Full Text »  |  PDF »

Heterogeneous Intrinsic Firing Properties of Vertebrate Retinal Ganglion Cells.

T. Tabata and M. Kano (2002)
J Neurophysiol 87, 30-41
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An ion channel 'addicted' to ether, alcohol and cocaine: the HERG potassium channel.

C. A Karle and J. Kiehn (2002)
Cardiovasc Res 53, 6-8
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Genetic Suppression of Seizure Susceptibility in Drosophila.

D. Kuebler, H. Zhang, X. Ren, and M. A. Tanouye (2001)
J Neurophysiol 86, 1211-1225
 |  Abstract »  |  Full Text »  |  PDF »

Mg2+ Modulates Voltage-Dependent Activation in Ether-a-Go-Go Potassium Channels by Binding between Transmembrane Segments S2 and S3.

W. R. Silverman, C.-Y. Tang, A. F. Mock, K.-B. Huh, and D. M. Papazian (2000)
J. Gen. Physiol. 116, 663-678
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A Novel Leg-Shaking Drosophila Mutant Defective in a Voltage-Gated K+ Current and Hypersensitive to Reactive Oxygen Species.

J. W. Wang, J. M. Humphreys, J. P. Phillips, A. J. Hilliker, and C.-F. Wu (2000)
J. Neurosci. 20, 5958-5964
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Molecular basis of functional voltage-gated K+ channel diversity in the mammalian myocardium.

J. M Nerbonne (2000)
J. Physiol. 525, 285-298
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LQT2 : Amplitude Reduction and Loss of Selectivity in the Tail That Wags the HERG Channel.

G. A. Robertson (2000)
Circ. Res. 86, 492-493
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Extracellular Mg2+ Modulates Slow Gating Transitions and the Opening of Drosophila Ether-a-Go-Go Potassium Channels.

C.-Y. Tang, F. Bezanilla, and D. M. Papazian (2000)
J. Gen. Physiol. 115, 319-338
 |  Abstract »  |  Full Text »  |  PDF »

Voltage-Gated Potassium Channels Activated During Action Potentials in Layer V Neocortical Pyramidal Neurons.

J. Kang, J. R. Huguenard, and D. A. Prince (2000)
J Neurophysiol 83, 70-80
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of Components of a Novel Subthreshold-Activating K+ Channel with a Unique Pattern of Expression in the Cerebral Cortex.

M. J. Saganich, E. V.-S. de Miera, M. S. Nadal, H. Baker, W. A. Coetzee, and B. Rudy (1999)
J. Neurosci. 19, 10789-10802
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Purification of an EH Domain-binding Protein from Rat Brain That Modulates the Gating of the Rat ether-a-go-go Channel.

E. T. Piros, L. Shen, and X.-Y. Huang (1999)
J. Biol. Chem. 274, 33677-33683
 |  Abstract »  |  Full Text »  |  PDF »

Block of an ether-a-go-go-Like K+ Channel by Imipramine Rescues egl-2 Excitation Defects in Caenorhabditis elegans.

D. Weinshenker, A. Wei, L. Salkoff, and J. H. Thomas (1999)
J. Neurosci. 19, 9831-9840
 |  Abstract »  |  Full Text »  |  PDF »

A plethora of mechanisms in the HERG-related long QT syndrome: Genetics meets electrophysiology.

D. M Roden and J. R Balser (1999)
Cardiovasc Res 44, 242-246
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New Ether-a-go-go K+ Channel Family Members Localized in Human Telencephalon.

A. Miyake, S. Mochizuki, H. Yokoi, M. Kohda, and K. Furuichi (1999)
J. Biol. Chem. 274, 25018-25025
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Unmasking of a Novel Potassium Current in Drosophila by a Mutation and Drugs.

A. Singh and S. Singh (1999)
J. Neurosci. 19, 6838-6843
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Mutational Analysis of the Shab-encoded Delayed Rectifier K+ Channels in Drosophila.

P. Hegde, G.-G. Gu, D. Chen, S. J. Free, and S. Singh (1999)
J. Biol. Chem. 274, 22109-22113
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Auxiliary Hyperkinetic beta  Subunit of K+ Channels: Regulation of Firing Properties and K+ Currents in Drosophila Neurons.

W.-D. Yao and C.-F. Wu (1999)
J Neurophysiol 81, 2472-2484
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Functional Analysis of a Mouse Brain Elk-Type K+ Channel.

M. C. Trudeau, S. A. Titus, J. L. Branchaw, B. Ganetzky, and G. A. Robertson (1999)
J. Neurosci. 19, 2906-2918
 |  Abstract »  |  Full Text »  |  PDF »

Cloning and functional expression of rat ether-a-go-go-like K+ channel genes.

B. Engeland, A. Neu, J. Ludwig, J. Roeper, and O. Pongs (1998)
J. Physiol. 513, 647-654
 |  Abstract »  |  Full Text »  |  PDF »

A Ca2+/Calmodulin-Dependent Protein Kinase Modulates Drosophila Photoreceptor K+ Currents: A Role in Shaping the Photoreceptor Potential.

A. Peretz, I. Abitbol, A. Sobko, C.-F. Wu, and B. Attali (1998)
J. Neurosci. 18, 9153-9162
 |  Abstract »  |  Full Text »  |  PDF »

Cloning of a mammalian elk potassium channel gene and EAG mRNA distribution in rat sympathetic ganglia.

W. Shi, H.-S. Wang, Z. Pan, R. S Wymore, I. S Cohen, D. McKinnon, and J. E Dixon (1998)
J. Physiol. 511, 675-682
 |  Abstract »  |  Full Text »  |  PDF »

KCR1, a Membrane Protein That Facilitates Functional Expression of Non-inactivating K+ Currents Associates with Rat EAG Voltage-dependent K+ Channels.

N. Hoshi, H. Takahashi, M. Shahidullah, S. Yokoyama, and H. Higashida (1998)
J. Biol. Chem. 273, 23080-23085
 |  Abstract »  |  Full Text »  |  PDF »

Transfer of rapid inactivation and sensitivity to the class III antiarrhythmic drug E-4031 from HERG to M-eag channels.

I. M Herzberg, M. C Trudeau, and G. A Robertson (1998)
J. Physiol. 511, 3-14
 |  Abstract »  |  Full Text »  |  PDF »

The K+ Channel Gene Ether a Go-Go Is Required for the Transduction of a Subset of Odorants in Adult Drosophila melanogaster.

A. E. Dubin, M. M. Liles, and G. L. Harris (1998)
J. Neurosci. 18, 5603-5613
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Ether-a-go-go Channels Present in Photoreceptors Reveals Similarity to IKx, a K+ Current in Rod Inner Segments.

S. Frings, N. Brull, C. Dzeja, A. Angele, V. Hagen, U. B. Kaupp, and A. Baumann (1998)
J. Gen. Physiol. 111, 583-599
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Genetic Dissection of Functional Contributions of Specific Potassium Channel Subunits in Habituation of an Escape Circuit in Drosophila.

J. E. Engel and C.-F. Wu (1998)
J. Neurosci. 18, 2254-2267
 |  Abstract »  |  Full Text »  |  PDF »

A State-independent Interaction between Ligand and a Conserved Arginine Residue in Cyclic Nucleotide-gated Channels Reveals a Functional Polarity of the Cyclic Nucleotide Binding Site.

G. R. Tibbs, D. T. Liu, B. G. Leypold, and S. A. Siegelbaum (1998)
J. Biol. Chem. 273, 4497-4505
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Interactive cloning with the SH3 domain of N-src identifies a new brain specific ion channel protein, with homology to Eag and cyclic nucleotide-gated channels.

B. Santoro, S. G. N. Grant, D. Bartsch, and E. R. Kandel (1997)
PNAS 94, 14815-14820
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Two Nervous System-Specific Members of the erg Potassium Channel Gene Family.

W. Shi, R. S. Wymore, H.-S. Wang, Z. Pan, I. S. Cohen, D. McKinnon, and J. E. Dixon (1997)
J. Neurosci. 17, 9423-9432
 |  Abstract »  |  Full Text »  |  PDF »

Two Isoforms of the Mouse Ether-a-go-go–Related Gene Coassemble to Form Channels With Properties Similar to the Rapidly Activating Component of the Cardiac Delayed Rectifier K+ Current.

B. London, M. C. Trudeau, K. P. Newton, A. K. Beyer, N. G. Copeland, D. J. Gilbert, N. A. J enkins, C. A. Satler, and G. A. Robertson (1997)
Circ. Res. 81, 870-878
 |  Abstract »  |  Full Text »

Regulation of the human ether-a-gogo related gene (HERG) K+ channels by reactive oxygen species.

M. Taglialatela, P. Castaldo, S. Iossa, A. Pannaccione, A. Fresi, E. Ficker, and L. Annunziato (1997)
PNAS 94, 11698-11703
 |  Abstract »  |  Full Text »  |  PDF »

Quantitative Single-Cell-Reverse Transcription-PCR Demonstrates That A-Current Magnitude Varies as a Linear Function of shal Gene Expression in Identified Stomatogastric Neurons.

D. J. Baro, R. M. Levini, M. T. Kim, A. R. Willms, C. C. Lanning, H. E. Rodriguez, and R. M. Harris-Warrick (1997)
J. Neurosci. 17, 6597-6610
 |  Abstract »  |  Full Text »  |  PDF »

Muscarinic Modulation of Spike Backpropagation in the Apical Dendrites of Hippocampal CA1 Pyramidal Neurons.

H. Tsubokawa and W. N. Ross (1997)
J. Neurosci. 17, 5782-5791
 |  Abstract »  |  Full Text »  |  PDF »

Presynaptic Recordings from Drosophila: Correlatin of Macroscopic and Single-Channel K+ Currents.

M. Martinez-Padron and A. Ferrus (1997)
J. Neurosci. 17, 3412-3424
 |  Abstract »  |  Full Text »  |  PDF »

Transfer of Voltage Independence from a Rat Olfactory Channel to the Drosophila Ether-a-go-go K+ Channel.

C.-Y. Tang and D. M. Papazian (1997)
J. Gen. Physiol. 109, 301-311
 |  Abstract »  |  Full Text »  |  PDF »

The Drosophila erg K+ Channel Polypeptide Is Encoded by the Seizure Locus.

S. A. Titus, J. W. Warmke, and B. Ganetzky (1997)
J. Neurosci. 17, 875-881
 |  Abstract »  |  Full Text »  |  PDF »

The Human Delta 1261 Mutation of the HERG Potassium Channel Results in a Truncated Protein That Contains a Subunit Interaction Domain and Decreases the Channel Expression.

X. Li, J. Xu, and M. Li (1997)
J. Biol. Chem. 272, 705-708
 |  Abstract »  |  Full Text »  |  PDF »

Determination of Key Structural Requirements of a K+ Channel Pore.

R. L. Nakamura, J. A. Anderson, and R. F. Gaber (1997)
J. Biol. Chem. 272, 1011-1018
 |  Abstract »  |  Full Text »  |  PDF »

A neurotransmitter transporter encoded by the Drosophila inebriated gene.

H. Soehnge, X. Huang, M. Becker, P. Whitley, D. Conover, and M. Stern (1996)
PNAS 93, 13262-13267
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Mechanisms in the Long-QT Syndrome: Current Knowledge, Gaps, and Future Directions.

D. M. Roden, R. Lazzara, M. Rosen, P. J. Schwartz, J. Towbin, and G. M. Vincent (1996)
Circulation 94, 1996-2012
 |  Abstract »  |  Full Text »

Long QT Syndrome Patients With Gene Mutations.

M. R. Rosen (1995)
Circulation 92, 3373-3375
 |  Full Text »

HERG, a human inward rectifier in the voltage-gated potassium channel family.

M. Trudeau, J. Warmke, B Ganetzky, and G. Robertson (1995)
Science 269, 92-95
 |  Abstract »  |  PDF »

A functional connection between the pores of distantly related ion channels as revealed by mutant K+ channels.

L Heginbotham, T Abramson, and R MacKinnon (1992)
Science 258, 1152-1155
 |  Abstract »  |  PDF »

Similarities in amino acid sequences of Drosophila eag and cyclic nucleotide-gated channels.

H. Guy, Durell SR, J Warmke, R Drysdale, and B Ganetzky (1991)
Science 254, 730
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A component of calcium-activated potassium channels encoded by the Drosophila slo locus.

N. Atkinson, G. Robertson, and B Ganetzky (1991)
Science 253, 551-555
 |  Abstract »  |  PDF »

Alteration of four identified K+ currents in Drosophila muscle by mutations in eag.

Y Zhong and C. Wu (1991)
Science 252, 1562-1564
 |  Abstract »  |  PDF »

Control of Drosophila perineurial glial growth by interacting neurotransmitter-mediated signaling pathways.

J. Yager, S. Richards, D. S. Hekmat-Scafe, D. D. Hurd, V. Sundaresan, D. R. Caprette, W. M. Saxton, J. R. Carlson, and M. Stern (2001)
PNAS 98, 10445-10450
 |  Abstract »  |  Full Text »  |  PDF »

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