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Science 17 May 1991:
Vol. 252. no. 5008, pp. 958 - 961
DOI: 10.1126/science.2035025

Articles

Science, Vol 252, Issue 5008, 958-961
Copyright © 1991 by American Association for the Advancement of Science


articles

Site-specific recombination between homologous chromosomes in Drosophila

KG Golic

Department of Molecular Genetics and Cell Biology, Howard Hughes Medical Institute, University of Chicago, IL 60637.

The ability to mark a cell and its descendants genetically so that the resulting cell clone can be distinguished from neighboring cells facilitates studies in animal biology and development. A method of generating clones by inducing homologous mitotic recombination in Drosophila with a site-specific yeast recombinase is described. This method allows for frequent mosaicism after mitotic exchange is induced at predefined sites in the genome.


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Dynamics of the sub-nuclear distribution of Modulo and the regulation of position-effect variegation by nucleolus in Drosophila.
L Perrin, O Demakova, L Fanti, S Kallenbach, S Saingery, N. Mal'ceva, S Pimpinelli, I Zhimulev, and J Pradel (1998)
J. Cell Sci. 111, 2753-2761
   Abstract »    PDF »
Identifying loci required for follicular patterning using directed mosaics.
J. Duffy, D. Harrison, and N Perrimon (1998)
Development 125, 2263-2271
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Genetic Analysis of brahma: The Drosophila Homolog of the Yeast Chromatin Remodeling Factor SWI2/SNF2.
(1998)
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eyelid antagonizes wingless signaling during Drosophila development and has homology to the Bright family of DNA-binding proteins.
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Development 124, 4361-4371
   Abstract »    PDF »
Hedgehog acts by distinct gradient and signal relay mechanisms to organise cell type and cell polarity in the Drosophila abdomen.
G Struhl, D. Barbash, and P. Lawrence (1997)
Development 124, 2155-2165
   Abstract »    PDF »
The microtubule motor cytoplasmic dynein is required for spindle orientation during germline cell divisions and oocyte differentiation in Drosophila.
M McGrail and T. Hays (1997)
Development 124, 2409-2419
   Abstract »    PDF »
Hedgehog activity, independent of decapentaplegic, participates in wing disc patterning.
J. Mullor, M Calleja, J Capdevila, and I Guerrero (1997)
Development 124, 1227-1237
   Abstract »    PDF »
klingon, a novel member of the Drosophila immunoglobulin superfamily, is required for the development of the R7 photoreceptor neuron.
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Development 124, 781-792
   Abstract »    PDF »
The spalt gene links the A/P compartment boundary to a linear adult structure in the Drosophila wing.
M. Sturtevant, B Biehs, E Marin, and E Bier (1997)
Development 124, 21-32
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Compartmental organization of the Drosophila genital imaginal discs.
E. Chen and B. Baker (1997)
Development 124, 205-218
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Delta is a ventral to dorsal signal complementary to Serrate, another Notch ligand, in Drosophila wing formation..
D Doherty, G Feger, S Younger-Shepherd, L Y Jan, and Y N Jan (1996)
Genes & Dev. 10, 421-434
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Pointed, an ETS domain transcription factor, negatively regulates the EGF receptor pathway in Drosophila oogenesis.
A. Morimoto, K. Jordan, K Tietze, J. Britton, E. O'Neill, and H Ruohola-Baker (1996)
Development 122, 3745-3754
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The Drosophila decapentaplegic and short gastrulation genes function antagonistically during adult wing vein development.
K Yu, M. Sturtevant, B Biehs, V Francois, R. Padgett, R. Blackman, and E Bier (1996)
Development 122, 4033-4044
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The germ line regulates somatic cyst cell proliferation and fate during Drosophila spermatogenesis.
P Gonczy and S DiNardo (1996)
Development 122, 2437-2447
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DNA topoisomerase and recombinase activities in Nae I restriction endonuclease.
K Jo and M. Topal (1995)
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The Drosophila tumor suppressor gene warts encodes a homolog of human myotonic dystrophy kinase and is required for the control of cell shape and proliferation..
R W Justice, O Zilian, D F Woods, M Noll, and P J Bryant (1995)
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Role of the morphogenetic furrow in establishing polarity in the Drosophila eye.
F Chanut and U Heberlein (1995)
Development 121, 4085-4094
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Creating a Drosophila wing de novo, the role of engrailed, and the compartment border hypothesis.
T Tabata, C Schwartz, E Gustavson, Z Ali, and T. Kornberg (1995)
Development 121, 3359-3369
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Sequential organizing activities of engrailed, hedgehog and decapentaplegic in the Drosophila wing.
M Zecca, K Basler, and G Struhl (1995)
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Identifying tumor suppressors in genetic mosaics: the Drosophila lats gene encodes a putative protein kinase.
T Xu, W Wang, S Zhang, R. Stewart, and W Yu (1995)
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Dual functions of wingless in the Drosophila leg imaginal disc.
E. Wilder and N Perrimon (1995)
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Mechanisms of cell rearrangement and cell recruitment in Drosophila ovary morphogenesis and the requirement of bric a brac.
D Godt and F. Laski (1995)
Development 121, 173-187
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Characterization of Star and its interactions with sevenless and EGF receptor during photoreceptor cell development in Drosophila.
A. Kolodkin, A. Pickup, D. Lin, C. Goodman, and U Banerjee (1994)
Development 120, 1731-1745
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Null alleles reveal novel requirements for Bic-D during Drosophila oogenesis and zygotic development.
B Ran, R Bopp, and B Suter (1994)
Development 120, 1233-1242
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pannier, a negative regulator of achaete and scute in Drosophila, encodes a zinc finger protein with homology to the vertebrate transcription factor GATA-1.
P. Ramain, P. Heitzler, M. Haenlin, and P. Simpson (1993)
Development 119, 1277-1291
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Autosomal P[ovoD1] dominant female-sterile insertions in Drosophila and their use in generating germ-line chimeras.
T. B. Chou, E. Noll, and N. Perrimon (1993)
Development 119, 1359-1369
   Abstract »    PDF »
Ectopic expression of seven-up causes cell fate changes during ommatidial assembly.
Y Hiromi, M Mlodzik, S. West, G. Rubin, and C. Goodman (1993)
Development 118, 1123-1135
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A role for the Drosophila segment polarity gene armadillo in cell adhesion and cytoskeletal integrity during oogenesis.
M Peifer, S Orsulic, D Sweeton, and E Wieschaus (1993)
Development 118, 1191-1207
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Analysis of genetic mosaics in developing and adult Drosophila tissues.
T Xu and G. Rubin (1993)
Development 117, 1223-1237
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Characterization of Sequences Responsible for trans-Inactivation of the Drosophila brown Gene.
L.E. Martin-Morris, K. Loughney, E.O. Kershisnik, G. Poortinga, and S. Henikoff (1993)
Cold Spring Harb Symp Quant Biol 58, 577-584
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Presenilin-mediated transmembrane cleavage is required for Notch signal transduction in Drosophila.
G. Struhl and I. Greenwald (2001)
PNAS 98, 229-234
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