Science 8 June 1990: Vol. 248. no. 4960, pp. 1227 - 1230 DOI: 10.1126/science.2112266

Prev | Table of Contents | Next

Articles

CCR7-mediated migration of developing thymocytes to the medulla is essential for negative selection to tissue-restricted antigens.

T. Nitta, S. Nitta, Y. Lei, M. Lipp, and Y. Takahama (2009)
PNAS 106, 17129-17133
 |  Abstract »  |  Full Text »  |  PDF »

Gamma Interferon Signaling in Macrophage Lineage Cells Regulates Central Nervous System Inflammation and Chemokine Production.

A. A. Lin, P. K. Tripathi, A. Sholl, M. B. Jordan, and D. A. Hildeman (2009)
J. Virol. 83, 8604-8615
 |  Abstract »  |  Full Text »  |  PDF »

Aberrant Selection and Function of Invariant NKT Cells in the Absence of AP-1 Transcription Factor Fra-2.

V. J. Lawson, D. Maurice, J. D. Silk, V. Cerundolo, and K. Weston (2009)
J. Immunol. 183, 2575-2584
 |  Abstract »  |  Full Text »  |  PDF »

CD8 T Cells in Old Mice Contribute to the Innate Immune Response to Mycobacterium tuberculosis via Interleukin-12p70-Dependent and Antigen-Independent Production of Gamma Interferon.

B. Vesosky, E. K. Rottinghaus, C. Davis, and J. Turner (2009)
Infect. Immun. 77, 3355-3363
 |  Abstract »  |  Full Text »  |  PDF »

Immunopathological Basis of Lymphocytic Choriomeningitis Virus-Induced Chorioretinitis and Keratitis.

M. S. Zinkernagel, B. Bolinger, P. Krebs, L. Onder, S. Miller, and B. Ludewig (2009)
J. Virol. 83, 159-166
 |  Abstract »  |  Full Text »  |  PDF »

Increased Susceptibility to Mycobacterium avium in Hemochromatosis Protein HFE-Deficient Mice.

S. Gomes-Pereira, P. N. Rodrigues, R. Appelberg, and M. S. Gomes (2008)
Infect. Immun. 76, 4713-4719
 |  Abstract »  |  Full Text »  |  PDF »

{beta}2-Microglobulin Signaling Blockade Inhibited Androgen Receptor Axis and Caused Apoptosis in Human Prostate Cancer Cells.

W.-C. Huang, J. J. Havel, H. E. Zhau, W. P. Qian, H.-W. Lue, C.-Y. Chu, T. Nomura, and L. W.K. Chung (2008)
Clin. Cancer Res. 14, 5341-5347
 |  Abstract »  |  Full Text »  |  PDF »

{beta}2-Microglobulin Deficient Mice Catabolize IgG More Rapidly Than FcRn-{alpha}-Chain Deficient Mice.

J. Kim, C. L. Bronson, M. A. Wani, T. M. Oberyszyn, S. Mohanty, C. Chaudhury, W. L. Hayton, J. M. Robinson, and C. L. Anderson (2008)
Experimental Biology and Medicine 233, 603-609
 |  Abstract »  |  Full Text »  |  PDF »

Identification of discrete tumor-induced myeloid-derived suppressor cell subpopulations with distinct T cell-suppressive activity.

K. Movahedi, M. Guilliams, J. Van den Bossche, R. Van den Bergh, C. Gysemans, A. Beschin, P. De Baetselier, and J. A. Van Ginderachter (2008)
Blood 111, 4233-4244
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Regulation of Experimental Autoimmune Encephalomyelitis by NK Cells: Alteration of Primary Adaptive Responses.

R. Winkler-Pickett, H. A. Young, J. M. Cherry, J. Diehl, J. Wine, T. Back, W. E. Bere, A. T. Mason, and J. R. Ortaldo (2008)
J. Immunol. 180, 4495-4506
 |  Abstract »  |  Full Text »  |  PDF »

Neuritogenic Effects of T Cell-Derived IL-3 on Mouse Splenic Sympathetic Neurons In Vivo.

Y. Kannan-Hayashi, K. Okamura, S. Hattori, M. Kuwamura, E. Higuchi, H. Terayama, M. Moriyama, M. Mukamoto, M. Okada, Y. Ohsugi, et al. (2008)
J. Immunol. 180, 4227-4234
 |  Abstract »  |  Full Text »  |  PDF »

Expression of Nonclassical Class I Major Histocompatibility Genes Defines a Tripartite Organization of the Mouse Vomeronasal System.

T. Ishii and P. Mombaerts (2008)
J. Neurosci. 28, 2332-2341
 |  Abstract »  |  Full Text »  |  PDF »

Class II-Restricted Protective Immunity Induced by Malaria Sporozoites.

G. A. Oliveira, K. A. Kumar, J. M. Calvo-Calle, C. Othoro, D. Altszuler, V. Nussenzweig, and E. H. Nardin (2008)
Infect. Immun. 76, 1200-1206
 |  Abstract »  |  Full Text »  |  PDF »

A CD8+/CD103high T Cell Subset Regulates TNF-Mediated Chronic Murine Ileitis.

J. Ho, C. C. Kurtz, M. Naganuma, P. B. Ernst, F. Cominelli, and J. Rivera-Nieves (2008)
J. Immunol. 180, 2573-2580
 |  Abstract »  |  Full Text »  |  PDF »

Replication of Beta- and Gammaretroviruses Is Restricted in I/LnJ Mice via the Same Genetic Mechanism.

L. K. Case, L. Petell, L. Yurkovetskiy, A. Purdy, K. J. Savage, and T. V. Golovkina (2008)
J. Virol. 82, 1438-1447
 |  Abstract »  |  Full Text »  |  PDF »

A Stat5b transgene is capable of inducing CD8+ lymphoblastic lymphoma in the absence of normal TCR/MHC signaling.

K. Bessette, M. L. Lang, R. A. Fava, M. Grundy, J. Heinen, L. Horne, R. Spolski, A. Al-Shami, H. C. Morse III, W. J. Leonard, et al. (2008)
Blood 111, 344-350
 |  Abstract »  |  Full Text »  |  PDF »

CD83 influences cell-surface MHC class II expression on B cells and other antigen-presenting cells.

Y. Kuwano, C. M. Prazma, N. Yazawa, R. Watanabe, N. Ishiura, A. Kumanogoh, H. Okochi, K. Tamaki, M. Fujimoto, and T. F. Tedder (2007)
Int. Immunol. 19, 977-992
 |  Abstract »  |  Full Text »  |  PDF »

Frontiers in Nephrology: The Varied Faces of Natural Killer Cells in Transplantation Contributions to Both Allograft Immunity and Tolerance.

J. N. Beilke and R. G. Gill (2007)
J. Am. Soc. Nephrol. 18, 2262-2267
 |  Abstract »  |  Full Text »  |  PDF »

An Impaired Breeding Phenotype in Mice with a Genetic Deletion of Beta-2 Microglobulin and Diminished MHC Class I Expression: Role in Reproductive Fitness.

J. C. Cooper, G. B. Dealtry, M. A. Ahmed, P. C. Arck, B. F. Klapp, S. M. Blois, and N. Fernandez (2007)
Biol Reprod 77, 274-279
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of CD8+ T Cell Development by Thymus-Specific Proteasomes.

S. Murata, K. Sasaki, T. Kishimoto, S.-i. Niwa, H. Hayashi, Y. Takahama, and K. Tanaka (2007)
Science 316, 1349-1353
 |  Abstract »  |  Full Text »  |  PDF »

Accelerated Transferrin Degradation in HFE-Deficient Mice Is Associated with Increased Transferrin Saturation.

C. Chaudhury, J. Kim, S. Mehnaz, M. A. Wani, T. M. Oberyszyn, C. L. Bronson, S. Mohanty, W. L. Hayton, J. M. Robinson, and C. L. Anderson (2006)
J. Nutr. 136, 2993-2998
 |  Abstract »  |  Full Text »  |  PDF »

Accumulation of Immunosuppressive CD11b+ Myeloid Cells Correlates with the Failure to Prevent Tumor Growth in the Anterior Chamber of the Eye.

K. C. McKenna and J. A. Kapp (2006)
J. Immunol. 177, 1599-1608
 |  Abstract »  |  Full Text »  |  PDF »

Agonist Ligands Expressed by Thymic Epithelium Enhance Positive Selection of Regulatory T Lymphocytes from Precursors with a Normally Diverse TCR Repertoire.

J. Ribot, P. Romagnoli, and J. P. M. van Meerwijk (2006)
J. Immunol. 177, 1101-1107
 |  Abstract »  |  Full Text »  |  PDF »

Scientific and clinical opportunities for modeling blood disorders with embryonic stem cells.

M. W. Lensch and G. Q. Daley (2006)
Blood 107, 2605-2612
 |  Abstract »  |  Full Text »  |  PDF »

Familial hypercatabolic hypoproteinemia caused by deficiency of the neonatal Fc receptor, FcRn, due to a mutant beta2-microglobulin gene.

M. A. Wani, L. D. Haynes, J. Kim, C. L. Bronson, C. Chaudhury, S. Mohanty, T. A. Waldmann, J. M. Robinson, and C. L. Anderson (2006)
PNAS 103, 5084-5089
 |  Abstract »  |  Full Text »  |  PDF »

Expression of m157, a Murine Cytomegalovirus-Encoded Putative Major Histocompatibility Class I (MHC-I)-Like Protein, Is Independent of Viral Regulation of Host MHC-I.

S. K. Tripathy, H. R. C. Smith, E. A. Holroyd, J. T. Pingel, and W. M. Yokoyama (2006)
J. Virol. 80, 545-550
 |  Abstract »  |  Full Text »  |  PDF »

CD8 T Cell-Mediated Lung Damage in Response to the Extracellular Pathogen Pneumocystis Is Dependent on MHC Class I Expression by Radiation-Resistant Lung Cells.

N. N. Meissner, F. E. Lund, S. Han, and A. Harmsen (2005)
J. Immunol. 175, 8271-8279
 |  Abstract »  |  Full Text »  |  PDF »

Molecular Signature of Recent Thymic Selection Events on Effector and Regulatory CD4+ T Lymphocytes.

P. Romagnoli, D. Hudrisier, and J. P. M. van Meerwijk (2005)
J. Immunol. 175, 5751-5758
 |  Abstract »  |  Full Text »  |  PDF »

{gamma}{delta} T cell homeostasis is established in competition with {alpha}{beta} T cells and NK cells.

J. D. French, C. L. Roark, W. K. Born, and R. L. O'Brien (2005)
PNAS 102, 14741-14746
 |  Abstract »  |  Full Text »  |  PDF »

Analyzing Expression of Perforin, Runx3, and Thpok Genes during Positive Selection Reveals Activation of CD8-Differentiation Programs by MHC II-Signaled Thymocytes.

X. Liu, B. J. Taylor, G. Sun, and R. Bosselut (2005)
J. Immunol. 175, 4465-4474
 |  Abstract »  |  Full Text »  |  PDF »

Mitochondrial DNA segregation in hematopoietic lineages does not depend on MHC presentation of mitochondrially encoded peptides.

B. J. Battersby, M. E. Redpath, and E. A. Shoubridge (2005)
Hum. Mol. Genet. 14, 2587-2594
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Bim by TCR Signals in CD4/CD8 Double-Positive Thymocytes.

A. Bunin, F. W. Khwaja, and G. J. Kersh (2005)
J. Immunol. 175, 1532-1539
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic Cells Cross-Present Exogenous Fungal Antigens to Stimulate a Protective CD8 T Cell Response in Infection by Histoplasma capsulatum.

J.-S. Lin, C.-W. Yang, D.-W. Wang, and B. A. Wu-Hsieh (2005)
J. Immunol. 174, 6282-6291
 |  Abstract »  |  Full Text »  |  PDF »

A CD8+ T Cell Heptaepitope Minigene Vaccine Induces Protective Immunity against Chlamydia pneumoniae.

I. Pinchuk, B. C. Starcher, B. Livingston, A. Tvninnereim, S. Wu, E. Appella, J. Sidney, A. Sette, and B. Wizel (2005)
J. Immunol. 174, 5729-5739
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T cells mediate aortic allograft vasculopathy by direct killing and an interferon-{gamma}-dependent indirect pathway.

A. I. Skaro, R. S. Liwski, J. Zhou, E. L. Vessie, T. D.G. Lee, and G. M. Hirsch (2005)
Cardiovasc Res 65, 283-291
 |  Abstract »  |  Full Text »  |  PDF »

From The Cover: A role for MHC class I molecules in synaptic plasticity and regeneration of neurons after axotomy.

A. L. R. Oliveira, S. Thams, O. Lidman, F. Piehl, T. Hokfelt, K. Karre, H. Linda, and S. Cullheim (2004)
PNAS 101, 17843-17848
 |  Abstract »  |  Full Text »  |  PDF »

Centromeric Repositioning of Coreceptor Loci Predicts Their Stable Silencing and the CD4/CD8 Lineage Choice.

M. Merkenschlager, S. Amoils, E. Roldan, A. Rahemtulla, E. O'Connor, A. G. Fisher, and K. E. Brown (2004)
J. Exp. Med. 200, 1437-1444
 |  Abstract »  |  Full Text »  |  PDF »

A Nonclassical MHC Class I Molecule Restricts CTL-Mediated Rejection of a Syngeneic Melanoma Tumor.

E. Y. Chiang and I. Stroynowski (2004)
J. Immunol. 173, 4394-4401
 |  Abstract »  |  Full Text »  |  PDF »

Defined {alpha}{beta} T Cell Receptors with Distinct Ligand Specificities Do Not Require Those Ligands to Signal Double Negative Thymocyte Differentiation.

B. Erman, T. I. Guinter, and A. Singer (2004)
J. Exp. Med. 199, 1719-1724
 |  Abstract »  |  Full Text »  |  PDF »

Infection-Induced Expansion of a MHC Class Ib-Dependent Intestinal Intraepithelial {gamma}{delta} T Cell Subset.

A. Davies, S. Lopez-Briones, H. Ong, C. O'Neil-Marshall, F. A. Lemonnier, K. Nagaraju, E. S. Metcalf, and M. J. Soloski (2004)
J. Immunol. 172, 6828-6837
 |  Abstract »  |  Full Text »  |  PDF »

Comparative Study of Brain CD8+ T Cells Induced by Sporozoites and Those Induced by Blood-Stage Plasmodium berghei ANKA Involved in the Development of Cerebral Malaria.

S. Bagot, F. Nogueira, A. Collette, V. do Rosario, F. Lemonier, P.-A. Cazenave, and S. Pied (2004)
Infect. Immun. 72, 2817-2826
 |  Abstract »  |  Full Text »  |  PDF »

Essential role of MHC II-independent CD4+ T cells, IL-4 and STAT6 in contact hypersensitivity induced by fluorescein isothiocyanate in the mouse.

K. Takeshita, T. Yamasaki, S. Akira, F. Gantner, and K. B. Bacon (2004)
Int. Immunol. 16, 685-695
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxic-T-Lymphocyte Human Papillomavirus Type 16 E5 Peptide with CpG-Oligodeoxynucleotide Can Eliminate Tumor Growth in C57BL/6 Mice.

Y.-F. Chen, C.-W. Lin, Y.-P. Tsao, and S.-L. Chen (2004)
J. Virol. 78, 1333-1343
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T Cells Mediate Recovery and Immunopathology in West Nile Virus Encephalitis.

Y. Wang, M. Lobigs, E. Lee, and A. Mullbacher (2003)
J. Virol. 77, 13323-13334
 |  Abstract »  |  Full Text »  |  PDF »

Functional Genomic Analysis of Remyelination Reveals Importance of Inflammation in Oligodendrocyte Regeneration.

H. A. Arnett, Y. Wang, G. K. Matsushima, K. Suzuki, and J. P.-Y. Ting (2003)
J. Neurosci. 23, 9824-9832
 |  Abstract »  |  Full Text »  |  PDF »

In Vivo Treatment of Class II MHC-Deficient Mice with Anti-TCR Antibody Restores the Generation of Circulating CD4 T Cells and Optimal Architecture of Thymic Medulla.

M. Nasreen, T. Ueno, F. Saito, and Y. Takahama (2003)
J. Immunol. 171, 3394-3400
 |  Abstract »  |  Full Text »  |  PDF »

T Cells Cause Acute Immunopathology and Are Required for Long-Term Survival in Mouse Adenovirus Type 1-Induced Encephalomyelitis.

M. L. Moore, C. C. Brown, and K. R. Spindler (2003)
J. Virol. 77, 10060-10070
 |  Abstract »  |  Full Text »  |  PDF »

Apoptosis by Neglect of CD4+ Th Cells in Granulomas: A Novel Effector Mechanism Involved in the Control of Egg-Induced Immunopathology in Murine Schistosomiasis.

L. I. Rutitzky, G. A. Mirkin, and M. J. Stadecker (2003)
J. Immunol. 171, 1859-1867
 |  Abstract »  |  Full Text »  |  PDF »

Impaired thymic negative selection causes autoimmune graft-versus-host disease.

T. Teshima, P. Reddy, C. Liu, D. Williams, K. R. Cooke, and J. L. M. Ferrara (2003)
Blood 102, 429-435
 |  Abstract »  |  Full Text »  |  PDF »

Vaccine Immunity to Pathogenic Fungi Overcomes the Requirement for CD4 Help in Exogenous Antigen Presentation to CD8+ T Cells: Implications for Vaccine Development in Immune-deficient Hosts.

M. Wuthrich, H. I. Filutowicz, T. Warner, G. S. Deepe Jr., and B. S. Klein (2003)
J. Exp. Med. 197, 1405-1416
 |  Abstract »  |  Full Text »  |  PDF »

Memory Phenotype of CD8+ T Cells in MHC Class Ia-Deficient Mice.

Z. Kurepa, J. Su, and J. Forman (2003)
J. Immunol. 170, 5414-5420
 |  Abstract »  |  Full Text »  |  PDF »

{beta}2-Microglobulin-Associated Regulation of Interferon-{gamma} and Virus-Specific Immunoglobulin G Confer Resistance Against the Development of Chronic Coxsackievirus Myocarditis.

K. Klingel, J.-J. Schnorr, M. Sauter, G. Szalay, and R. Kandolf (2003)
Am. J. Pathol. 162, 1709-1720
 |  Abstract »  |  Full Text »  |  PDF »

IL-15 availability conditions homeostasis of peripheral natural killer T cells.

T. Ranson, C. A. J. Vosshenrich, E. Corcuff, O. Richard, V. Laloux, A. Lehuen, and J. P. Di Santo (2003)
PNAS 100, 2663-2668
 |  Abstract »  |  Full Text »  |  PDF »

The Major Histocompatibility Complex-related Fc Receptor for IgG (FcRn) Binds Albumin and Prolongs Its Lifespan.

C. Chaudhury, S. Mehnaz, J. M. Robinson, W. L. Hayton, D. K. Pearl, D. C. Roopenian, and C. L. Anderson (2003)
J. Exp. Med. 197, 315-322
 |  Abstract »  |  Full Text »  |  PDF »

Bone Marrow B Cell Apoptosis During In Vivo Influenza Virus Infection Requires TNF-{alpha} and Lymphotoxin-{alpha}.

L. M. Sedger, S. Hou, S. R. Osvath, M. B. Glaccum, J. J. Peschon, N. van Rooijen, and L. Hyland (2002)
J. Immunol. 169, 6193-6201
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Fc{gamma}R Signaling in the K/B x N Serum Transfer Model of Arthritis.

M. Corr and B. Crain (2002)
J. Immunol. 169, 6604-6609
 |  Abstract »  |  Full Text »  |  PDF »

Transfection of Macrophage Inflammatory Protein 1{alpha} into B16 F10 Melanoma Cells Inhibits Growth of Pulmonary Metastases But Not Subcutaneous Tumors.

H. W. van Deventer, J. S. Serody, K. P. McKinnon, C. Clements, W. J. Brickey, and J. P.-Y. Ting (2002)
J. Immunol. 169, 1634-1639
 |  Abstract »  |  Full Text »  |  PDF »

The Developmentally Regulated Expression of Twisted Gastrulation Reveals a Role for Bone Morphogenetic Proteins in the Control of T Cell Development.

D. Graf, S. Nethisinghe, D. B. Palmer, A. G. Fisher, and M. Merkenschlager (2002)
J. Exp. Med. 196, 163-171
 |  Abstract »  |  Full Text »  |  PDF »

The Role of Proinflammatory Cytokines in Wasting Disease During Lymphocytic Choriomeningitis Virus Infection.

C. Kamperschroer and D. G. Quinn (2002)
J. Immunol. 169, 340-349
 |  Abstract »  |  Full Text »  |  PDF »

Skin Graft Rejection Elicited by {beta}2-Microglobulin as a Minor Transplantation Antigen Involves Multiple Effector Pathways: Role of Fas-Fas Ligand Interactions and Th2-Dependent Graft Eosinophil Infiltrates.

M. Surquin, A. Le Moine, V. Flamand, N. Nagy, K. Rombaut, F.-X. Demoor, P. Stordeur, I. Salmon, J.-C. Guery, M. Goldman, et al. (2002)
J. Immunol. 169, 500-506
 |  Abstract »  |  Full Text »  |  PDF »

The variable, CH1, CH2 and CH3 domains of Ig heavy chain are dispensable for pre-BCR function in transgenic mice.

S. A. Muljo and M. S. Schlissel (2002)
Int. Immunol. 14, 577-584
 |  Abstract »  |  Full Text »  |  PDF »

Fas-Dependent Elimination of Nonselected CD8 Cells and lpr Disease.

L. A. Trimble, K. A. Prince, G. A. Pestano, J. Daley, and H. Cantor (2002)
J. Immunol. 168, 4960-4967
 |  Abstract »  |  Full Text »  |  PDF »

Probing for Membrane Domains in the Endoplasmic Reticulum: Retention and Degradation of Unassembled MHC Class I Molecules.

E. T. Spiliotis, T. Pentcheva, and M. Edidin (2002)
Mol. Biol. Cell 13, 1566-1581
 |  Abstract »  |  Full Text »  |  PDF »

Naive T cells proliferate strongly in neonatal mice in response to self-peptide/self-MHC complexes.

A. Le Campion, C. Bourgeois, F. Lambolez, B. Martin, S. Leaument, N. Dautigny, C. Tanchot, C. Penit, and B. Lucas (2002)
PNAS 99, 4538-4543
 |  Abstract »  |  Full Text »  |  PDF »

Cutting Edge: Single-Chain Trimers of MHC Class I Molecules Form Stable Structures That Potently Stimulate Antigen-Specific T Cells and B Cells.

Y. Y. L. Yu, N. Netuschil, L. Lybarger, J. M. Connolly, and T. H. Hansen (2002)
J. Immunol. 168, 3145-3149
 |  Abstract »  |  Full Text »  |  PDF »

CD53, a thymocyte selection marker whose induction requires a lower affinity TCR-MHC interaction than CD69, but is up-regulated with slower kinetics.

K. L. Puls, K. A. Hogquist, N. Reilly, and M. D. Wright (2002)
Int. Immunol. 14, 249-258
 |  Abstract »  |  Full Text »  |  PDF »

Up-Regulation of MHC Class I Expression Accompanies but Is Not Required for Spontaneous Myopathy in Dysferlin-Deficient SJL/J Mice.

C. A. Kostek, J. A. Dominov, and J. B. Miller (2002)
Am. J. Pathol. 160, 833-839
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of AML1 Transcription Factor Drives Thymocytes into the CD8 Single-Positive Lineage.

K. Hayashi, N. Abe, T. Watanabe, M. Obinata, M. Ito, T. Sato, S. Habu, and M. Satake (2001)
J. Immunol. 167, 4957-4965
 |  Abstract »  |  Full Text »  |  PDF »

Sensory Adaptation in Naive Peripheral CD4 T Cells.

K. Smith, B. Seddon, M. A. Purbhoo, R. Zamoyska, A. G. Fisher, and M. Merkenschlager (2001)
J. Exp. Med. 194, 1253-1262
 |  Abstract »  |  Full Text »  |  PDF »

A Naturally Processed Mitochondrial Self-Peptide in Complex with Thymic Mhc Molecules Functions as a Selecting Ligand for a Viral-Specific T Cell Receptor.

T. Sasada, Y. Ghendler, J. M. Neveu, W. S. Lane, and E. L. Reinherz (2001)
J. Exp. Med. 194, 883-892
 |  Abstract »  |  Full Text »  |  PDF »

Deficiency in {beta}2-Microglobulin, But Not CD1, Accelerates Spontaneous Lupus Skin Disease While Inhibiting Nephritis in MRL-Faslpr Mice: An Example of Disease Regulation at the Organ Level.

O. T. M. Chan, V. Paliwal, J. M. McNiff, S.-H. Park, A. Bendelac, and M. J. Shlomchik (2001)
J. Immunol. 167, 2985-2990
 |  Abstract »  |  Full Text »  |  PDF »

Multiple Paths for Activation of Naive CD8+ T Cells: CD4-Independent Help.

B. Wang, C. C. Norbury, R. Greenwood, J. R. Bennink, J. W. Yewdell, and J. A. Frelinger (2001)
J. Immunol. 167, 1283-1289
 |  Abstract »  |  Full Text »  |  PDF »

Autonomous Maturation of {alpha}/{beta} T Lineage Cells in the Absence of Cooh-Terminal Src Kinase (Csk).

C. Schmedt and A. Tarakhovsky (2001)
J. Exp. Med. 193, 815-826
 |  Abstract »  |  Full Text »  |  PDF »

MHC-II-Independent CD4+ T Cells Induce Colitis in Immunodeficient RAG-/- Hosts.

Z. Trobonjaca, F. Leithauser, P. Moller, H. Bluethmann, Y. Koezuka, H. R. MacDonald, and J. Reimann (2001)
J. Immunol. 166, 3804-3812
 |  Abstract »  |  Full Text »  |  PDF »

Idiotype-encoding recombinant adenoviruses provide protective immunity against murine B-cell lymphomas.

J. M. Timmerman, C. B. Caspar, S. L. Lambert, A. D. Syrengelas, and R. Levy (2001)
Blood 97, 1370-1377
 |  Abstract »  |  Full Text »  |  PDF »

Activated p56lck Directs Maturation of Both CD4 and CD8 Single-Positive Thymocytes.

S. J. Sohn, K. A. Forbush, X. C. Pan, and R. M. Perlmutter (2001)
J. Immunol. 166, 2209-2217
 |  Abstract »  |  Full Text »  |  PDF »

Expression of the DMT1 (NRAMP2/DCT1) iron transporter in mice with genetic iron overload disorders.

F. Canonne-Hergaux, J. E. Levy, M. D. Fleming, L. K. Montross, N. C. Andrews, and P. Gros (2001)
Blood 97, 1138-1140
 |  Abstract »  |  Full Text »  |  PDF »

Cytotoxic T Cells Play No Essential Role in Acute Rejection of Orthotopic Corneal Allografts in Mice.

J. Yamada, B. R. Ksander, and J. W. Streilein (2001)
Invest. Ophthalmol. Vis. Sci. 42, 386-392
 |  Abstract »  |  Full Text »

Annexin V Binds to Positively Selected B Cells.

S. R. Dillon, A. Constantinescu, and M. S. Schlissel (2001)
J. Immunol. 166, 58-71
 |  Abstract »  |  Full Text »  |  PDF »

Response to RAG-Mediated V(D)J Cleavage by NBS1 and {gamma}-H2AX.

H. T. Chen, A. Bhandoola, M. J. Difilippantonio, J. Zhu, M. J. Brown, X. Tai, E. P. Rogakou, T. M. Brotz, W. M. Bonner, T. Ried, et al. (2000)
Science 290, 1962-1964
 |  Abstract »  |  Full Text »

The Quantity of TCR Signal Determines Positive Selection and Lineage Commitment of T Cells.

N. Watanabe, H. Arase, M. Onodera, P. S. Ohashi, and T. Saito (2000)
J. Immunol. 165, 6252-6261
 |  Abstract »  |  Full Text »  |  PDF »

Dendritic Cells Prime In Vivo Alloreactive CD4 T Lymphocytes Toward Type 2 Cytokine- and TGF-{beta}-Producing Cells in the Absence of CD8 T Cell Activation.

G. Foucras, J. D. Coudert, C. Coureau, and J.-C. Guery (2000)
J. Immunol. 165, 4994-5003
 |  Abstract »  |  Full Text »  |  PDF »

Induction of CD8 T Cells by Vaccination with Recombinant Adenovirus Expressing Human Papillomavirus Type 16 E5 Gene Reduces Tumor Growth.

D.-W. Liu, Y.-P. Tsao, C.-H. Hsieh, J.-T. Hsieh, J. T. Kung, C.-L. Chiang, S.-J. Huang, and S.-L. Chen (2000)
J. Virol. 74, 9083-9089
 |  Abstract »  |  Full Text »

Premature Expression of T Cell Receptor (Tcr){alpha}{beta} Suppresses Tcr{gamma}{delta} Gene Rearrangement but Permits Development of {gamma}{delta} Lineage T Cells.

K. Terrence, C. P. Pavlovich, E. O. Matechak, and B.J. Fowlkes (2000)
J. Exp. Med. 192, 537-548
 |  Abstract »  |  Full Text »  |  PDF »

Response of Murine {gamma}{delta} T Cells to the Synthetic Polypeptide Poly-Glu50Tyr50 1.

C. T. Cady, M. Lahn, M. Vollmer, M. Tsuji, S. J. Seo, C. L. Reardon, R. L. O'Brien, and W. K. Born (2000)
J. Immunol. 165, 1790-1798
 |  Abstract »  |  Full Text »  |  PDF »

{alpha}{beta}TCR+ Cells Are a Minimal Fraction of Peripheral CD8+ Pool in MHC Class I-Deficient Mice.

D. Nesic, F. R. Santori, and S. Vukmanovic (2000)
J. Immunol. 165, 1896-1901
 |  Abstract »  |  Full Text »  |  PDF »

Programming for cytotoxic effector function occurs concomitantly with CD4 extinction during CD8+ T cell differentiation in the thymus.

A. Bhandoola, B. Kithiganahalli, L. Granger, and A. Singer (2000)
Int. Immunol. 12, 1035-1040
 |  Abstract »  |  Full Text »  |  PDF »

Relative contributions of distinct MHC class I-dependent cell populations in protection to tuberculosis infection in mice.

A. O. Sousa, R. J. Mazzaccaro, R. G. Russell, F. K. Lee, O. C. Turner, S. Hong, L. Van Kaer, and B. R. Bloom (2000)
PNAS 97, 4204-4208
 |  Abstract »  |  Full Text »  |  PDF »

Positive Selection Is Limited by Available Peptide-Dependent MHC Conformations.

H. E. Stefanski, S. C. Jameson, and K. A. Hogquist (2000)
J. Immunol. 164, 3519-3526
 |  Abstract »  |  Full Text »  |  PDF »

Crucial Role of TNF-{alpha} in CD8 T Cell-Mediated Elimination of 3LL-A9 Lewis Lung Carcinoma Cells In Vivo.

A. Prevost-Blondel, E. Roth, F. M. Rosenthal, and H. Pircher (2000)
J. Immunol. 164, 3645-3651
 |  Abstract »  |  Full Text »  |  PDF »

Recombinant Adeno-Associated Virus Expressing Human Papillomavirus Type 16 E7 Peptide DNA Fused with Heat Shock Protein DNA as a Potential Vaccine for Cervical Cancer.

D.-W. Liu, Y.-P. Tsao, J. T. Kung, Y.-A. Ding, H.-K. Sytwu, X. Xiao, and S.-L. Chen (2000)
J. Virol. 74, 2888-2894
 |  Abstract »  |  Full Text »

Recognition of a Sequestered Self Peptide by Influenza Virus-Specific CD8+ Cytolytic T Lymphocytes.

R. Fan, S. S. Tykodi, and T. J. Braciale (2000)
J. Immunol. 164, 1669-1680
 |  Abstract »  |  Full Text »  |  PDF »

Annexin V Binds to Viable B Cells and Colocalizes with a Marker of Lipid Rafts upon B Cell Receptor Activation.

S. R. Dillon, M. Mancini, A. Rosen, and M. S. Schlissel (2000)
J. Immunol. 164, 1322-1332
 |  Abstract »  |  Full Text »  |  PDF »

Tetracycline-controllable Selection of CD4+ T Cells: Half-Life and Survival Signals in the Absence of Major Histocompatibility Complex Class II Molecules.

D. Witherden, N. van Oers, C. Waltzinger, A. Weiss, C. Benoist, and D. Mathis (2000)
J. Exp. Med. 191, 355-364
 |  Abstract »  |  PDF »

Comparative Contribution of CD1 on the Development of CD4+ and CD8+ T Cell Compartments.

B. Wang, T. Chun, and C.-R. Wang (2000)
J. Immunol. 164, 739-745
 |  Abstract »  |  Full Text »  |  PDF »

Thymocyte Maturation Is Regulated by the Activity of the Helix-Loop-Helix Protein, E47.

G. Bain, M. W. Quong, R. S. Soloff, S. M. Hedrick, and C. Murre (1999)
J. Exp. Med. 190, 1605-1616
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Lineage Commitment Distinct from Positive Selection.

R. Keefe, V. Dave, D. Allman, D. Wiest, and D. J. Kappes (1999)
Science 286, 1149-1153
 |  Abstract »  |  Full Text »

To Advertise   |   Find Products