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Science 14 July 1989: Vol. 245. no. 4914, pp. 160 - 164 DOI: 10.1126/science.2665076
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Articles
Science, Vol 245, Issue 4914, 160-164
Copyright © 1989 by American Association for the Advancement of Science
DNA mismatch correction in a defined system
RS Lahue,
KG Au,
and
P Modrich
Department of Biochemistry, Duke University Medical Center, Durham, NC 27710.
DNA mismatch correction is a strand-specific process involving recognition of noncomplementary Watson-Crick nucleotide pairs and participation of widely separated DNA sites. The Escherichia coli methyl-directed reaction has been reconstituted in a purified system consisting of MutH, MutL, and MutS proteins, DNA helicase II, single-strand DNA binding protein, DNA polymerase III holoenzyme, exonuclease I, DNA ligase, along with ATP (adenosine triphosphate), and the four deoxynucleoside triphosphates. This set of proteins can process seven of the eight base-base mismatches in a strand-specific reaction that is directed by the state of methylation of a single d(GATC) sequence located 1 kilobase from the mispair.
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| Abstract »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
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| Abstract »
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| Abstract »
| PDF »
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- I. Biswas, C. Ban, K. G. Fleming, J. Qin, J. W. Lary, D. A. Yphantis, W. Yang, and P. Hsieh (1999)
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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| Abstract »
| Full Text »
| PDF »
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- L. E. Mechanic, M. C. Hall, and S. W. Matson (1999)
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274, 12488-12498
| Abstract »
| Full Text »
| PDF »
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- L. E. Mechanic, M. E. Latta, and S. W. Matson (1999)
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181, 2519-2526
| Abstract »
| Full Text »
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274, 7474-7481
| Abstract »
| Full Text »
| PDF »
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- S. Guerrette, S. Acharya, and R. Fishel (1999)
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| Abstract »
| Full Text »
| PDF »
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- H. T. Tran, D. A. Gordenin, and M. A. Resnick (1999)
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19, 2000-2007
| Abstract »
| Full Text »
| PDF »
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- M. C. Hall and S. W. Matson (1999)
J. Biol. Chem.
274, 1306-1312
| Abstract »
| Full Text »
| PDF »
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- B. Studamire, T. Quach, and E. Alani (1998)
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18, 7590-7601
| Abstract »
| Full Text »
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- L. Worth Jr., T. Bader, J. Yang, and S. Clark (1998)
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| Abstract »
| Full Text »
| PDF »
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- R. Fishel (1998)
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12, 2096-2101
| Full Text »
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- M. Yamaguchi, V. Dao, and P. Modrich (1998)
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273, 9197-9201
| Abstract »
| Full Text »
| PDF »
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- V. Dao and P. Modrich (1998)
J. Biol. Chem.
273, 9202-9207
| Abstract »
| Full Text »
| PDF »
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- C. B. McGill, S. L. Holbeck, and J. N. Strathern (1998)
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148, 1525-1533
| Abstract »
| Full Text »
| PDF »
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- A. Bhui-Kaur, M. F. Goodman, and J. Tower (1998)
Mol. Cell. Biol.
18, 1436-1443
| Abstract »
| Full Text »
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- Y.-L. Lin, M. K. K. Shivji, C. Chen, R. Kolodner, R. D. Wood, and A. Dutta (1998)
J. Biol. Chem.
273, 1453-1461
| Abstract »
| Full Text »
| PDF »
- Functional Properties of Replication Fork Assemblies Established by the Bacteriophage lambda O and P Replication Proteins.
- K. M. Stephens and R. McMacken (1997)
J. Biol. Chem.
272, 28800-28813
| Abstract »
| Full Text »
| PDF »
- Extended Abstracts.
- (1997)
Toxicol Pathol
25, 674-696
| PDF »
- Methyl-directed Repair of Mismatched Small Heterologous Sequences in Cell Extracts from Escherichia coli.
- W.-h. Fang, J.-Y. Wu, and M.-J. Su (1997)
J. Biol. Chem.
272, 22714-22720
| Abstract »
| Full Text »
| PDF »
- Mutation of a Highly Conserved Arginine in Motif IV of Escherichia coli DNA Helicase II Results in an ATP-binding Defect.
- M. C. Hall and S. W. Matson (1997)
J. Biol. Chem.
272, 18614-18620
| Abstract »
| Full Text »
| PDF »
- A Point Mutation in Escherichia coli DNA Helicase II Renders the Enzyme Nonfunctional in Two DNA Repair Pathways. EVIDENCE FOR INITIATION OF UNWINDING FROM A NICK IN VIVO.
- R. M. Brosh Jr. and S. W. Matson (1997)
J. Biol. Chem.
272, 572-579
| Abstract »
| Full Text »
| PDF »
- A Partially Functional DNA Helicase II Mutant Defective in Forming Stable Binary Complexes with ATP and DNA. A ROLE FOR HELICASE MOTIF III.
- R. M. Brosh Jr. and S. W. Matson (1996)
J. Biol. Chem.
271, 25360-25368
| Abstract »
| Full Text »
| PDF »
- Biochemistry and genetics of eukaryotic mismatch repair..
- R Kolodner (1996)
Genes & Dev.
10, 1433-1442
| PDF »
- Identification and Characterization of a Thermostable MutS Homolog from Thermus aquaticus.
- I. Biswas and P. Hsieh (1996)
J. Biol. Chem.
271, 5040-5048
| Abstract »
| Full Text »
| PDF »
- DnaX Complex of Escherichia coli DNA Polymerase III Holoenzyme.
- H. G. Dallmann, R. L. Thimmig, and C. S. McHenry (1995)
J. Biol. Chem.
270, 29555-29562
| Abstract »
| Full Text »
| PDF »
- Appropriate partners make good matches.
- P Karran (1995)
Science
268, 1857-1858
| PDF »
- HU Protein of Escherichia coli Binds Specifically to DNA That Contains Single-strand Breaks or Gaps.
- B. Castaing, C. Zelwer, J. Laval, and S. Boiteux (1995)
J. Biol. Chem.
270, 10291-10296
| Abstract »
| Full Text »
| PDF »
- A role for exonuclease I from S. pombe in mutation avoidance and mismatch correction.
- P Szankasi and G. Smith (1995)
Science
267, 1166-1169
| Abstract »
| PDF »
- The Saccharomyces cerevisiae Msh2 protein specifically binds to duplex oligonucleotides containing mismatched DNA base pairs and insertions..
- E Alani, N W Chi, and R Kolodner (1995)
Genes & Dev.
9, 234-247
| Abstract »
| PDF »
- Greater susceptibility to mutations in lagging strand of DNA replication in Escherichia coli than in leading strand.
- X Veaute and R. Fuchs (1993)
Science
261, 598-600
| Abstract »
| PDF »
- Mismatch Repair and Genetic Stability in Human Cells.
- W.-H. Fang, G.-M. Li, M. Longley, J. Holmes, W. Thilly, and P. Modrich (1993)
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58, 597-603
| Abstract »
| PDF »
- Escherichia coli MutL Loads DNA Helicase II onto DNA.
- L. E. Mechanic, B. A. Frankel, and S. W. Matson (2000)
J. Biol. Chem.
275, 38337-38346
| Abstract »
| Full Text »
| PDF »
- Excision of 3' Termini by the Trex1 and TREX2 3'right-arrow5' Exonucleases. CHARACTERIZATION OF THE RECOMBINANT PROTEINS.
- D. J. Mazur and F. W. Perrino (2001)
J. Biol. Chem.
276, 17022-17029
| Abstract »
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- The Interaction of DNA Mismatch Repair Proteins with Human Exonuclease I.
- C. Schmutte, M. M. Sadoff, K.-S. Shim, S. Acharya, and R. Fishel (2001)
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276, 33011-33018
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- M. Viswanathan, V. Burdett, C. Baitinger, P. Modrich, and S. T. Lovett (2001)
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276, 31053-31058
| Abstract »
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- In vivo requirement for RecJ, ExoVII, ExoI, and ExoX in methyl-directed mismatch repair.
- V. Burdett, C. Baitinger, M. Viswanathan, S. T. Lovett, and P. Modrich (2001)
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