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Science 17 March 1989:
Vol. 243. no. 4897, pp. 1464 - 1466
DOI: 10.1126/science.2648569

Articles

Science, Vol 243, Issue 4897, 1464-1466
Copyright © 1989 by American Association for the Advancement of Science


articles

The neutrophil-activating protein (NAP-1) is also chemotactic for T lymphocytes

CG Larsen, AO Anderson, E Appella, JJ Oppenheim, and K Matsushima

Laboratory of Molecular Immunoregulation, National Cancer Institute, Frederick, MD 21701.

T lymphocyte chemotactic factor (TCF) was purified to homogeneity from the conditioned media of phytohemagglutinin-stimulated human blood mononuclear leukocytes by a sequence of chromatography procedures. The amino-terminal amino acid sequence of the purified TCF showed identity with neutrophil-activating protein (NAP-1). Both TCF and recombinant NAP-1 (rNAP-1) were chemotactic for neutrophils and T lymphocytes in vitro supporting the identity of TCF with NAP-1. Injection of rNAP-1 into lymphatic drainage areas of lymph nodes in Fisher rats caused accelerated emigration of only lymphocytes in high endothelial venules. Intradermal injection of rNAP-1 caused dose-dependent accumulation of neutrophils and lymphocytes.


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   Abstract »    PDF »
Ca2+-Dependent Production and Release of IL-8 in Human Neutrophils.
D. B. Kuhns, H. A. Young, E. K. Gallin, and J. I. Gallin (1998)
J. Immunol. 161, 4332-4339
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Elevated Concentrations of Eotaxin and Interleukin-5 in Human Neurocysticercosis.
C. A. W. Evans, H. H. Garcia, A. Hartnell, R. H. Gilman, P. J. Jose, M. Martinez, D. G. Remick, T. J. Williams, and J. S. Friedland (1998)
Infect. Immun. 66, 4522-4525
   Abstract »    Full Text »    PDF »
Chemokines Induced by Infection of Mononuclear Phagocytes with Mycobacteria and Present in Lung Alveoli during Active Pulmonary Tuberculosis.
M. I. Sadek, E. Sada, Z. Toossi, S. K. Schwander, and E. A. Rich (1998)
Am. J. Respir. Cell Mol. Biol. 19, 513-521
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A monoclonal anti-interleukin 8 antibody (WS-4) inhibits cytokine response and acute lung injury in experimental severe acute necrotising pancreatitis in rabbits.
M O Osman, J U Kristensen, N O Jacobsen, S B Lausten, B Deleuran, M Deleuran, B Gesser, K Matsushima, C G Larsen, and S L Jensen (1998)
Gut 43, 232-239
   Abstract »    Full Text »    PDF »
High Fas ligand expression on lymphocytes in lesions of ulcerative colitis.
H Ueyama, T Kiyohara, N Sawada, K Isozaki, S Kitamura, S Kondo, J Miyagawa, S Kanayama, Y Shinomura, H Ishikawa, et al. (1998)
Gut 43, 48-55
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Individual Cell Analysis of the Cytokine Repertoire in Human Immunodeficiency Virus-1-Infected Monocytes/Macrophages by a Combination of Immunocytochemistry and In Situ Hybridization.
R. Esser, W. Glienke, R. Andreesen, R. E. Unger, M. Kreutz, H. Rubsamen-Waigmann, and H. von Briesen (1998)
Blood 91, 4752-4760
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Cyclic Stretch Upregulates Production of Interleukin-8 and Monocyte Chemotactic and Activating Factor/Monocyte Chemoattractant Protein-1 in Human Endothelial Cells.
M. Okada, A. Matsumori, K. Ono, Y. Furukawa, T. Shioi, A. Iwasaki, K. Matsushima, and S. Sasayama (1998)
Arterioscler Thromb Vasc Biol 18, 894-901
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Interleukin-8 in the Human Endometrium.
A. Arici, E. Seli, L. M. Senturk, L. S. Gutierrez, E. Oral, and H. S. Taylor (1998)
J. Clin. Endocrinol. Metab. 83, 1783-1787
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Nitric Oxide Inhibits Rhinovirus-Induced Cytokine Production and Viral Replication in a Human Respiratory Epithelial Cell Line.
S. P. Sanders, E. S. Siekierski, J. D. Porter, S. M. Richards, and D. Proud (1998)
J. Virol. 72, 934-942
   Abstract »    Full Text »    PDF »
T cell syncytia induced by HIV release. T cell chemoattractants: demonstration with a newly developed single cell chemotaxis chamber.
D. Shutt, L. Jenkins, E. Carolan, J Stapleton, K. Daniels, R. Kennedy, and D. Soll (1998)
J. Cell Sci. 111, 99-109
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Human Thyroid Fibroblasts Exhibit a Distinctive Phenotype in Culture: Characteristic Ganglioside Profile and Functional CD40 Expression.
T. J. Smith, G. D. Sempowski, C. S. Berenson, H. J. Cao, H.-S. Wang, and R. P. Phipps (1997)
Endocrinology 138, 5576-5588
   Abstract »    Full Text »    PDF »
Upregulation of Interleukin 8 by Oxygen-deprived Cells in Glioblastoma Suggests a Role in Leukocyte Activation, Chemotaxis, and Angiogenesis.
I. Desbaillets, A.-C. Diserens, N. d. Tribolet, M.-F. Hamou, and E. G. V. Meir (1997)
J. Exp. Med. 186, 1201-1212
   Abstract »    Full Text »    PDF »
Induction of various cytokines and development of severe mucosal inflammation by cagA gene positive Helicobacter pylori strains.
Y Yamaoka, M Kita, T Kodama, N Sawai, K Kashima, and J Imanishi (1997)
Gut 41, 442-451
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Interleukin-15 (IL-15) Induces IL-8 and Monocyte Chemotactic Protein 1 Production in Human Monocytes.
R. Badolato, A. N. Ponzi, M. Millesimo, L. D. Notarangelo, and T. Musso (1997)
Blood 90, 2804-2809
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Identification of Human Neutrophil-derived Cathepsin G and Azurocidin/CAP37 as Chemoattractants for Mononuclear Cells and Neutrophils.
O. Chertov, H. Ueda, L. L. Xu, K. Tani, W. J. Murphy, J. M. Wang, O.M. Z. Howard, T. J. Sayers, and J. J. Oppenheim (1997)
J. Exp. Med. 186, 739-747
   Abstract »    Full Text »    PDF »
Chemokines.
B. J. Rollins (1997)
Blood 90, 909-928
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Stimulation of Interleukin-8 Production by Okadaic Acid and Vanadate in a Human Promyelocyte Cell Line, an HL-60 Subline. POSSIBLE ROLE OF MITOGEN-ACTIVATED PROTEIN KINASE ON THE OKADAIC ACID-INDUCED NF-kappa B ACTIVATION.
Y. Sonoda, T. Kasahara, Y. Yamaguchi, K. Kuno, K. Matsushima, and N. Mukaida (1997)
J. Biol. Chem. 272, 15366-15372
   Abstract »    Full Text »    PDF »
Cloning and Characterization of a Novel Murine beta  Chemokine Receptor, D6. COMPARISON TO THREE OTHER RELATED MACROPHAGE INFLAMMATORY PROTEIN-1alpha RECEPTORS, CCR-1, CCR-3, AND CCR-5.
R. J. B. Nibbs, S. M. Wylie, I. B. Pragnell, and G. J. Graham (1997)
J. Biol. Chem. 272, 12495-12504
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Presence of Cyclophilin A in Synovial Fluids of Patients with Rheumatoid Arthritis.
A. Billich, G. Winkler, H. Aschauer, A. Rot, and P. Peichl (1997)
J. Exp. Med. 185, 975-980
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Macrophages Isolated From Human Atherosclerotic Plaques Produce IL-8, and Oxysterols May Have a Regulatory Function for IL-8 Production.
Y. Liu, L. M. Hulten, and O. Wiklund (1997)
Arterioscler Thromb Vasc Biol 17, 317-323
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CD4+ Lymphocytes Are Increased in the Sinus Mucosa of Children With Chronic Sinusitis.
P. V. Driscoll, R. M. Naclerio, and F. M. Baroody (1996)
Arch Otolaryngol Head Neck Surg 122, 1071-1076
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Interleukin-8 Production by Macrophages From Atheromatous Plaques.
J. Apostolopoulos, P. Davenport, and P. G. Tipping (1996)
Arterioscler Thromb Vasc Biol 16, 1007-1012
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Molecular Expression of the alpha-Chemokine Rabbit GRO in Escherichia coli and Characterization of Its Production by Lung Cells in Vitro and in Vivo.
M. C. Johnson II, O. Kajikawa, R. B. Goodman, V. A. Wong, S. M. Mongovin, W. B. Wong, R. Fox-Dewhurst, and T. R. Martin (1996)
J. Biol. Chem. 271, 10853-10858
   Abstract »    Full Text »    PDF »



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