Science 15 July 1988: Vol. 241. no. 4863, pp. 317 - 322 DOI: 10.1126/science.3291120

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Articles

A Role for Checkpoint Kinase-Dependent Rad26 Phosphorylation in Transcription-Coupled DNA Repair in Saccharomyces cerevisiae.

M. Taschner, M. Harreman, Y. Teng, H. Gill, R. Anindya, S. L. Maslen, J. M. Skehel, R. Waters, and J. Q. Svejstrup (2010)
Mol. Cell. Biol. 30, 436-446
 |  Abstract »  |  Full Text »  |  PDF »

How Telomeres Solve the End-Protection Problem.

T. de Lange (2009)
Science 326, 948-952
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae Rad6 Postreplication Repair and Siz1/Srs2 Homologous Recombination-Inhibiting Pathways Process DNA Damage That Arises in asf1 Mutants.

E. S. Kats, J. M. Enserink, S. Martinez, and R. D. Kolodner (2009)
Mol. Cell. Biol. 29, 5226-5237
 |  Abstract »  |  Full Text »  |  PDF »

A G2-Phase Microtubule-Damage Response in Fission Yeast.

F. R. Balestra and J. Jimenez (2008)
Genetics 180, 2073-2080
 |  Abstract »  |  Full Text »  |  PDF »

Structural and functional analysis of the Crb2-BRCT2 domain reveals distinct roles in checkpoint signaling and DNA damage repair.

M. L. Kilkenny, A. S. Dore, S. M. Roe, K. Nestoras, J. C.Y. Ho, F. Z. Watts, and L. H. Pearl (2008)
Genes & Dev. 22, 2034-2047
 |  Abstract »  |  Full Text »  |  PDF »

Distinct Phosphatases Mediate the Deactivation of the DNA Damage Checkpoint Kinase Rad53.

A. Travesa, A. Duch, and D. G. Quintana (2008)
J. Biol. Chem. 283, 17123-17130
 |  Abstract »  |  Full Text »  |  PDF »

Yeast mother cell-specific ageing, genetic (in)stability, and the somatic mutation theory of ageing.

P. Laun, C. V. Bruschi, J. Richard Dickinson, M. Rinnerthaler, G. Heeren, R. Schwimbersky, R. Rid, and M. Breitenbach (2007)
Nucleic Acids Res.
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms of Checkpoint Kinase Rad53 Inactivation after a Double-Strand Break in Saccharomyces cerevisiae.

G. Guillemain, E. Ma, S. Mauger, S. Miron, R. Thai, R. Guerois, F. Ochsenbein, and M.-C. Marsolier-Kergoat (2007)
Mol. Cell. Biol. 27, 3378-3389
 |  Abstract »  |  Full Text »  |  PDF »

Modelling the checkpoint response to telomere uncapping in budding yeast.

C.J Proctor, D.A Lydall, R.J Boys, C.S Gillespie, D.P Shanley, D.J Wilkinson, and T.B.L Kirkwood (2007)
J R Soc Interface 4, 73-90
 |  Abstract »  |  Full Text »  |  PDF »

Yeast Rtt109 Promotes Genome Stability by Acetylating Histone H3 on Lysine 56.

R. Driscoll, A. Hudson, and S. P. Jackson (2007)
Science 315, 649-652
 |  Abstract »  |  Full Text »  |  PDF »

The Spindle Assembly Checkpoint Regulates the Phosphorylation State of a Subset of DNA Checkpoint Proteins in Saccharomyces cerevisiae.

C. Clemenson and M.-C. Marsolier-Kergoat (2006)
Mol. Cell. Biol. 26, 9149-9161
 |  Abstract »  |  Full Text »  |  PDF »

The Tandem BRCT Domain of 53BP1 Is Not Required for Its Repair Function.

I. Ward, J.-E. Kim, K. Minn, C. C. Chini, G. Mer, and J. Chen (2006)
J. Biol. Chem. 281, 38472-38477
 |  Abstract »  |  Full Text »  |  PDF »

Contribution of Growth and Cell Cycle Checkpoints to Radiation Survival in Drosophila.

B. Jaklevic, L. Uyetake, W. Lemstra, J. Chang, W. Leary, A. Edwards, S. Vidwans, O. Sibon, and T. Tin Su (2006)
Genetics 174, 1963-1972
 |  Abstract »  |  Full Text »  |  PDF »

DNA Damage Checkpoints Are Involved in Postreplication Repair.

L. Barbour, L. G. Ball, K. Zhang, and W. Xiao (2006)
Genetics 174, 1789-1800
 |  Abstract »  |  Full Text »  |  PDF »

Phosphorylation of Rad55 on Serines 2, 8, and 14 Is Required for Efficient Homologous Recombination in the Recovery of Stalled Replication Forks.

K. Herzberg, V. I. Bashkirov, M. Rolfsmeier, E. Haghnazari, W. H. McDonald, S. Anderson, E. V. Bashkirova, J. R. Yates III, and W.-D. Heyer (2006)
Mol. Cell. Biol. 26, 8396-8409
 |  Abstract »  |  Full Text »  |  PDF »

Re-oxygenation Improves Hypoxia-induced Pulp Cell Arrest.

Y. Ueno, C. Kitamura, M. Terashita, and T. Nishihara (2006)
Journal of Dental Research 85, 824-828
 |  Abstract »  |  Full Text »  |  PDF »

The RAD6/BRE1 Histone Modification Pathway in Saccharomyces Confers Radiation Resistance Through a RAD51-Dependent Process That Is Independent of RAD18.

J. C. Game, M. S. Williamson, T. Spicakova, and J. M. Brown (2006)
Genetics 173, 1951-1968
 |  Abstract »  |  Full Text »  |  PDF »

A mitotic topoisomerase II checkpoint in budding yeast is required for genome stability but acts independently of Pds1/securin..

C. A. Andrews, A. C. Vas, B. Meier, J. F. Gimenez-Abian, L. A. Diaz-Martinez, J. Green, S. L. Erickson, K. E. VanderWaal, W.-S. Hsu, and D. J. Clarke (2006)
Genes & Dev. 20, 1162-1174
 |  Abstract »  |  Full Text »  |  PDF »

Linking uracil base excision repair and 5-fluorouracil toxicity in yeast.

L. Seiple, P. Jaruga, M. Dizdaroglu, and J. T. Stivers (2006)
Nucleic Acids Res. 34, 140-151
 |  Abstract »  |  Full Text »  |  PDF »

Cooperative Control of Crb2 by ATM Family and Cdc2 Kinases Is Essential for the DNA Damage Checkpoint in Fission Yeast.

T. M. Nakamura, B. A. Moser, L.-L. Du, and P. Russell (2005)
Mol. Cell. Biol. 25, 10721-10730
 |  Abstract »  |  Full Text »  |  PDF »

A haploid-specific transcriptional response to irradiation in Saccharomyces cerevisiae.

G. Mercier, N. Berthault, N. Touleimat, F. Kepes, G. Fourel, E. Gilson, and M. Dutreix (2005)
Nucleic Acids Res. 33, 6635-6643
 |  Abstract »  |  Full Text »  |  PDF »

Role of Dot1-Dependent Histone H3 Methylation in G1 and S Phase DNA Damage Checkpoint Functions of Rad9.

R. Wysocki, A. Javaheri, S. Allard, F. Sha, J. Cote, and S. J. Kron (2005)
Mol. Cell. Biol. 25, 8430-8443
 |  Abstract »  |  Full Text »  |  PDF »

hMOF Histone Acetyltransferase Is Required for Histone H4 Lysine 16 Acetylation in Mammalian Cells.

M. Taipale, S. Rea, K. Richter, A. Vilar, P. Lichter, A. Imhof, and A. Akhtar (2005)
Mol. Cell. Biol. 25, 6798-6810
 |  Abstract »  |  Full Text »  |  PDF »

DNA damage-induced mitotic catastrophe is mediated by the Chk1-dependent mitotic exit DNA damage checkpoint.

X. Huang, T. Tran, L. Zhang, R. Hatcher, and P. Zhang (2005)
PNAS 102, 1065-1070
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of 14-3-3 protein with Chk1 affects localization and checkpoint function.

S. Dunaway, H.-Y. Liu, and N. C. Walworth (2005)
J. Cell Sci. 118, 39-50
 |  Abstract »  |  Full Text »  |  PDF »

The adaptive imbalance to genotoxic stress: genome guardians rear their ugly heads.

L. J. Hofseth (2004)
Carcinogenesis 25, 1787-1793
 |  Abstract »  |  Full Text »  |  PDF »

Potentiation of Cytotoxicity of Topoisomerase I Poison by Concurrent and Sequential Treatment with the Checkpoint Inhibitor UCN-01 Involves Disparate Mechanisms Resulting in Either p53-Independent Clonogenic Suppression or p53-Dependent Mitotic Catastrophe.

A. N. Tse and G. K. Schwartz (2004)
Cancer Res. 64, 6635-6644
 |  Abstract »  |  Full Text »  |  PDF »

Design and synthesis of fluorescent substrates for human tyrosyl-DNA phosphodiesterase I.

M. C. Rideout, A. C. Raymond, and A. B. Burgin Jr (2004)
Nucleic Acids Res. 32, 4657-4664
 |  Abstract »  |  Full Text »  |  PDF »

Kinetochores Prevent Repair of UV Damage in Saccharomyces cerevisiae Centromeres.

C. Capiaghi, T. V. Ho, and F. Thoma (2004)
Mol. Cell. Biol. 24, 6907-6918
 |  Abstract »  |  Full Text »  |  PDF »

The Clp1p/Flp1p phosphatase ensures completion of cytokinesis in response to minor perturbation of the cell division machinery in Schizosaccharomyces pombe.

M. Mishra, J. Karagiannis, S. Trautmann, H. Wang, D. McCollum, and M. K. Balasubramanian (2004)
J. Cell Sci. 117, 3897-3910
 |  Abstract »  |  Full Text »  |  PDF »

Saccharomyces cerevisiae Rrm3p DNA Helicase Promotes Genome Integrity by Preventing Replication Fork Stalling: Viability of rrm3 Cells Requires the Intra-S-Phase Checkpoint and Fork Restart Activities.

J. Z. Torres, S. L. Schnakenberg, and V. A. Zakian (2004)
Mol. Cell. Biol. 24, 3198-3212
 |  Abstract »  |  Full Text »  |  PDF »

Association of Rad9 with Double-Strand Breaks through a Mec1-Dependent Mechanism.

T. Naiki, T. Wakayama, D. Nakada, K. Matsumoto, and K. Sugimoto (2004)
Mol. Cell. Biol. 24, 3277-3285
 |  Abstract »  |  Full Text »  |  PDF »

Cell Cycle Progression in G1 and S Phases Is CCR4 Dependent following Ionizing Radiation or Replication Stress in Saccharomyces cerevisiae.

T. J. Westmoreland, J. R. Marks, J. A. Olson Jr., E. M. Thompson, M. A. Resnick, and C. B. Bennett (2004)
Eukaryot. Cell 3, 430-446
 |  Abstract »  |  Full Text »  |  PDF »

Human Checkpoint Protein hRad9 Functions as a Negative Coregulator To Repress Androgen Receptor Transactivation in Prostate Cancer Cells.

L. Wang, C.-L. Hsu, J. Ni, P.-H. Wang, S. Yeh, P. Keng, and C. Chang (2004)
Mol. Cell. Biol. 24, 2202-2213
 |  Abstract »  |  Full Text »  |  PDF »

Mec1 and Rad53 Inhibit Formation of Single-Stranded DNA at Telomeres of Saccharomyces cerevisiae cdc13-1 Mutants.

X. Jia, T. Weinert, and D. Lydall (2004)
Genetics 166, 753-764
 |  Abstract »  |  Full Text »  |  PDF »

A domain of Rad9 specifically required for activation of Chk1 in budding yeast.

R. T. Blankley and D. Lydall (2004)
J. Cell Sci. 117, 601-608
 |  Abstract »  |  Full Text »  |  PDF »

Interaction of Saccharomyces Cdc13p with Pol1p, Imp4p, Sir4p and Zds2p is involved in telomere replication, telomere maintenance and cell growth control.

C.-L. Hsu, Y.-S. Chen, S.-Y. Tsai, P.-J. Tu, M.-J. Wang, and J.-J. Lin (2004)
Nucleic Acids Res. 32, 511-521
 |  Abstract »  |  Full Text »  |  PDF »

End Resection Initiates Genomic Instability in the Absence of Telomerase.

J. A. Hackett and C. W. Greider (2003)
Mol. Cell. Biol. 23, 8450-8461
 |  Abstract »  |  Full Text »  |  PDF »

Hiding at the ends of yeast chromosomes: telomeres, nucleases and checkpoint pathways.

D. Lydall (2003)
J. Cell Sci. 116, 4057-4065
 |  Abstract »  |  Full Text »  |  PDF »

Potential Role for 53BP1 in DNA End-joining Repair through Direct Interaction with DNA.

K. Iwabuchi, B. P. Basu, B. Kysela, T. Kurihara, M. Shibata, D. Guan, Y. Cao, T. Hamada, K. Imamura, P. A. Jeggo, et al. (2003)
J. Biol. Chem. 278, 36487-36495
 |  Abstract »  |  Full Text »  |  PDF »

The Checkpoint Protein Rad24 of Saccharomyces cerevisiae Is Involved in Processing Double-Strand Break Ends and in Recombination Partner Choice.

Y. Aylon and M. Kupiec (2003)
Mol. Cell. Biol. 23, 6585-6596
 |  Abstract »  |  Full Text »  |  PDF »

Expression deconvolution: A reinterpretation of DNA microarray data reveals dynamic changes in cell populations.

P. Lu, A. Nakorchevskiy, and E. M. Marcotte (2003)
PNAS 100, 10370-10375
 |  Abstract »  |  Full Text »  |  PDF »

XRad17 Is Required for the Activation of XChk1 But Not XCds1 during Checkpoint Signaling in Xenopus.

R. E. Jones, J. R. Chapman, C. Puligilla, J. M. Murray, A. M. Car, C. C. Ford, and H. D. Lindsay (2003)
Mol. Biol. Cell 14, 3898-3910
 |  Abstract »  |  Full Text »  |  PDF »

Mrc1 is a replication fork component whose phosphorylation in response to DNA replication stress activates Rad53.

A. J. Osborn and S. J. Elledge (2003)
Genes & Dev. 17, 1755-1767
 |  Abstract »  |  Full Text »  |  PDF »

The Rad51 Pathway of Telomerase-Independent Maintenance of Telomeres Can Amplify TG1-3 Sequences in yku and cdc13 Mutants of Saccharomyces cerevisiae.

N. Grandin and M. Charbonneau (2003)
Mol. Cell. Biol. 23, 3721-3734
 |  Abstract »  |  Full Text »  |  PDF »

A DNA-Damage-Induced Cell Cycle Checkpoint in Arabidopsis.

S. B. Preuss and A. B. Britt (2003)
Genetics 164, 323-334
 |  Abstract »  |  Full Text »  |  PDF »

Exposure of Single-stranded Telomeric DNA Causes G2/M Cell Cycle Arrest in Saccharomyces cerevisiae.

T.-L. Pang, C.-Y. Wang, C.-L. Hsu, M.-Y. Chen, and J.-J. Lin (2003)
J. Biol. Chem. 278, 9318-9321
 |  Abstract »  |  Full Text »  |  PDF »

Short Telomeres Induce a DNA Damage Response in Saccharomyces cerevisiae.

A. S. IJpma and C. W. Greider (2003)
Mol. Biol. Cell 14, 987-1001
 |  Abstract »  |  Full Text »  |  PDF »

NFBD1, a Novel Nuclear Protein with Signature Motifs of FHA and BRCT, and an Internal 41-Amino Acid Repeat Sequence, Is an Early Participant in DNA Damage Response.

Y. L. Shang, A. J. Bodero, and P.-L. Chen (2003)
J. Biol. Chem. 278, 6323-6329
 |  Abstract »  |  Full Text »  |  PDF »

Nuclear oscillations and nuclear filament formation accompany single-strand annealing repair of a dicentric chromosome in Saccharomyces cerevisiae.

D. A. Thrower, J. Stemple, E. Yeh, and K. Bloom (2003)
J. Cell Sci. 116, 561-569
 |  Abstract »  |  Full Text »  |  PDF »

Histone H3 and the Histone Acetyltransferase Hat1p Contribute to DNA Double-Strand Break Repair.

S. Qin and M. R. Parthun (2002)
Mol. Cell. Biol. 22, 8353-8365
 |  Abstract »  |  Full Text »  |  PDF »

A dominant-negative MEC3 mutant uncovers new functions for the Rad17 complex and Tel1.

M. Giannattasio, E. Sommariva, R. Vercillo, F. Lippi-Boncambi, G. Liberi, M. Foiani, P. Plevani, and M. Muzi-Falconi (2002)
PNAS 99, 12997-13002
 |  Abstract »  |  Full Text »  |  PDF »

DNA replication is required for the checkpoint response to damaged DNA in Xenopus egg extracts.

M. P. Stokes, R. Van Hatten, H. D. Lindsay, and W. M. Michael (2002)
J. Cell Biol. 158, 863-872
 |  Abstract »  |  Full Text »  |  PDF »

MEC3, MEC1, and DDC2 Are Essential Components of a Telomere Checkpoint Pathway Required for Cell Cycle Arrest during Senescence in Saccharomyces cerevisiae.

S. Enomoto, L. Glowczewski, and J. Berman (2002)
Mol. Biol. Cell 13, 2626-2638
 |  Abstract »  |  Full Text »  |  PDF »

Robust G1 checkpoint arrest in budding yeast: dependence on DNA damage signaling and repair.

J. N. F. Gerald, J. M. Benjamin, and S. J. Kron (2002)
J. Cell Sci. 115, 1749-1757
 |  Abstract »  |  Full Text »  |  PDF »

Inaugural Article: Suppression of genome instability by redundant S-phase checkpoint pathways in Saccharomycescerevisiae.

K. Myung and R. D. Kolodner (2002)
PNAS 99, 4500-4507
 |  Abstract »  |  Full Text »  |  PDF »

Involvement of RAD9-Dependent Damage Checkpoint Control in Arrest of Cell Cycle, Induction of Cell Death, and Chromosome Instability Caused by Defects in Origin Recognition Complex in Saccharomyces cerevisiae.

K. Watanabe, J. Morishita, K. Umezu, K. Shirahige, and H. Maki (2002)
Eukaryot. Cell 1, 200-212
 |  Abstract »  |  Full Text »  |  PDF »

Two Molecularly Distinct G2/M Checkpoints Are Induced by Ionizing Irradiation.

B. Xu, S.-T. Kim, D.-S. Lim, and M. B. Kastan (2002)
Mol. Cell. Biol. 22, 1049-1059
 |  Abstract »  |  Full Text »  |  PDF »

Cell-Based Assays for Identification of Novel Double-Strand Break-Inducing Agents.

H. M. Dunstan, C. Ludlow, S. Goehle, M. Cronk, P. Szankasi, D. R. H. Evans, J. A. Simon, and J. R. Lamb (2002)
J Natl Cancer Inst 94, 88-94
 |  Abstract »  |  Full Text »  |  PDF »

Binding and Partial Denaturing of G-quartet DNA by Cdc13p of Saccharomyces cerevisiae.

Y.-C. Lin, J.-W. Shih, C.-L. Hsu, and J.-J. Lin (2001)
J. Biol. Chem. 276, 47671-47674
 |  Abstract »  |  Full Text »  |  PDF »

DNA Damage-dependent and -independent Phosphorylation of the hRad9 Checkpoint Protein.

R. P. St.Onge, B. D. A. Besley, M. Park, R. Casselman, and S. Davey (2001)
J. Biol. Chem. 276, 41898-41905
 |  Abstract »  |  Full Text »  |  PDF »

Human Rad17 Is Phosphorylated upon DNA Damage and also Overexpressed in Primary Non-Small Cell Lung Cancer Tissues.

X. Wang, L. Wang, M. D. Callister, J. B. Putnam, L. Mao, and L. Li (2001)
Cancer Res. 61, 7417-7421
 |  Abstract »  |  Full Text »  |  PDF »

Genomic Expression Responses to DNA-damaging Agents and the Regulatory Role of the Yeast ATR Homolog Mec1p.

A. P. Gasch, M. Huang, S. Metzner, D. Botstein, S. J. Elledge, and P. O. Brown (2001)
Mol. Biol. Cell 12, 2987-3003
 |  Abstract »  |  Full Text »  |  PDF »

Mutations in SID2, a Novel Gene in Saccharomyces cerevisiae, Cause Synthetic Lethality With sic1 Deletion and May Cause a Defect During S Phase.

M. D. Jacobson, C. X. Munoz, K. S. Knox, B. E. Williams, L. L. Lu, F. R. Cross, and E. A. Vallen (2001)
Genetics 159, 17-33
 |  Abstract »  |  Full Text »  |  PDF »

Dicentric Chromosome Stretching during Anaphase Reveals Roles of Sir2/Ku in Chromatin Compaction in Budding Yeast.

D. A. Thrower and K. Bloom (2001)
Mol. Biol. Cell 12, 2800-2812
 |  Abstract »  |  Full Text »  |  PDF »

SIR Functions Are Required for the Toleration of an Unrepaired Double-Strand Break in a Dispensable Yeast Chromosome.

C. B. Bennett, J. R. Snipe, J. W. Westmoreland, and M. A. Resnick (2001)
Mol. Cell. Biol. 21, 5359-5373
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of mec1 Kinase-Deficient Mutants and of New Hypomorphic mec1 Alleles Impairing Subsets of the DNA Damage Response Pathway.

V. Paciotti, M. Clerici, M. Scotti, G. Lucchini, and M. P. Longhese (2001)
Mol. Cell. Biol. 21, 3913-3925
 |  Abstract »  |  Full Text »  |  PDF »

Rfc4 Interacts with Rpa1 and Is Required for Both DNA Replication and DNA Damage Checkpoints in Saccharomyces cerevisiae.

H.-S. Kim and S. J. Brill (2001)
Mol. Cell. Biol. 21, 3725-3737
 |  Abstract »  |  Full Text »  |  PDF »

p53 protein at the hub of cellular DNA damage response pathways through sequence-specific and non-sequence-specific DNA binding.

Y. Liu and M. Kulesz-Martin (2001)
Carcinogenesis 22, 851-860
 |  Abstract »  |  Full Text »  |  PDF »

Identification of a Saccharomyces cerevisiae Gene that Is Required for G1 Arrest in Response to the Lipid Oxidation Product Linoleic Acid Hydroperoxide*.

N. Alic, V. J. Higgins, and I. W. Dawes (2001)
Mol. Biol. Cell 12, 1801-1810
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae RAD9 cell cycle checkpoint gene is required for optimal repair of UV-induced pyrimidine dimers in both G1 and G2/M phases of the cell cycle.

N. M. Al-Moghrabi, I. S. Al-Sharif, and A. Aboussekhra (2001)
Nucleic Acids Res. 29, 2020-2025
 |  Abstract »  |  Full Text »  |  PDF »

Cell cycle progression and cell division are sensitive to hypoxia in Drosophila melanogaster embryos.

R. M. Douglas, T. Xu, and G. G. Haddad (2001)
Am J Physiol Regulatory Integrative Comp Physiol 280, R1555-R1563
 |  Abstract »  |  Full Text »  |  PDF »

Overexpression of CDC25B Overrides Radiation-induced G2-M Arrest and Results in Increased Apoptosis in Esophageal Cancer Cells.

H. Miyata, Y. Doki, H. Yamamoto, K. Kishi, H. Takemoto, Y. Fujiwara, T. Yasuda, M. Yano, M. Inoue, H. Shiozaki, et al. (2001)
Cancer Res. 61, 3188-3193
 |  Abstract »  |  Full Text »

The Short Life Span of Saccharomyces cerevisiae sgs1 and srs2 Mutants Is a Composite of Normal Aging Processes and Mitotic Arrest Due to Defective Recombination.

M. McVey, M. Kaeberlein, H. A. Tissenbaum, and L. Guarente (2001)
Genetics 157, 1531-1542
 |  Abstract »  |  Full Text »

Pie1, a Protein Interacting with Mec1, Controls Cell Growth and Checkpoint Responses in Saccharomyces cerevisiae.

T. Wakayama, T. Kondo, S. Ando, K. Matsumoto, and K. Sugimoto (2001)
Mol. Cell. Biol. 21, 755-764
 |  Abstract »  |  Full Text »  |  PDF »

Tof1p Regulates DNA Damage Responses During S Phase in Saccharomyces cerevisiae.

E. J. Foss (2001)
Genetics 157, 567-577
 |  Abstract »  |  Full Text »

Conversion of Normal To Malignant Phenotype: Telomere Shortening, Telomerase Activation, and Genomic Instability During Immortalization of Human Oral Keratinocytes.

M.K. Kang and M.-H. Park (2001)
Critical Reviews in Oral Biology & Medicine 12, 38-54
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Cell Cycle Progression by Swe1p and Hog1p Following Hypertonic Stress.

M. R. Alexander, M. Tyers, M. Perret, B. M. Craig, K. S. Fang, and M. C. Gustin (2001)
Mol. Biol. Cell 12, 53-62
 |  Abstract »  |  Full Text »

P53 Binding Protein 1 (53bp1) Is an Early Participant in the Cellular Response to DNA Double-Strand Breaks.

L. B. Schultz, N. H. Chehab, A. Malikzay, and T. D. Halazonetis (2000)
J. Cell Biol. 151, 1381-1390
 |  Abstract »  |  Full Text »  |  PDF »

Telomere-binding and Stn1p-interacting activities are required for the essential function of Saccharomyces cerevisiae Cdc13p.

M.-J. Wang, Y.-C. Lin, T.-L. Pang, J.-M. Lee, C.-C. Chou, and J.-J. Lin (2000)
Nucleic Acids Res. 28, 4733-4741
 |  Abstract »  |  Full Text »  |  PDF »

Yeast Mutants As a Model System for Identification of Determinants of Chemosensitivity.

P. Perego, G. S. Jimenez, L. Gatti, S. B. Howell, and F. Zunino (2000)
Pharmacol. Rev. 52, 477-492
 |  Abstract »  |  Full Text »  |  PDF »

CDC25B and p53 Are Independently Implicated in Radiation Sensitivity for Human Esophageal Cancers.

H. Miyata, Y. Doki, H. Shiozaki, M. Inoue, M. Yano, Y. Fujiwara, H. Yamamoto, K. Nishioka, K. Kishi, and M. Monden (2000)
Clin. Cancer Res. 6, 4859-4865
 |  Abstract »  |  Full Text »

Regulatory Networks Revealed by Transcriptional Profiling of Damaged Saccharomyces cerevisiae Cells: Rpn4 Links Base Excision Repair with Proteasomes.

S. A. Jelinsky, P. Estep, G. M. Church, and L. D. Samson (2000)
Mol. Cell. Biol. 20, 8157-8167
 |  Abstract »  |  Full Text »  |  PDF »

RB-Dependent S-Phase Response to DNA Damage.

K. E. Knudsen, D. Booth, S. Naderi, Z. Sever-Chroneos, A. F. Fribourg, I. C. Hunton, J. R. Feramisco, J. Y. J. Wang, and E. S. Knudsen (2000)
Mol. Cell. Biol. 20, 7751-7763
 |  Abstract »  |  Full Text »  |  PDF »

Rfc5, in Cooperation with Rad24, Controls DNA Damage Checkpoints throughout the Cell Cycle in Saccharomyces cerevisiae.

T. Naiki, T. Shimomura, T. Kondo, K. Matsumoto, and K. Sugimoto (2000)
Mol. Cell. Biol. 20, 5888-5896
 |  Abstract »  |  Full Text »  |  PDF »

The checkpoint protein Ddc2, functionally related to S. pombe Rad26, interacts with Mec1 and is regulated by Mec1-dependent phosphorylation in budding yeast.

V. Paciotti, M. Clerici, G. Lucchini, and M. P. Longhese (2000)
Genes & Dev. 14, 2046-2059
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POB3 Is Required for Both Transcription and Replication in the Yeast Saccharomyces cerevisiae.

M. B. Schlesinger and T. Formosa (2000)
Genetics 155, 1593-1606
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Genetic Analyses of Schizosaccharomyces pombe dna2+ Reveal That Dna2 Plays an Essential Role in Okazaki Fragment Metabolism.

H.-Y. Kang, E. Choi, S.-H. Bae, K.-H. Lee, B.-S. Gim, H.-D. Kim, C. Park, S. A. MacNeill, and Y.-S. Seo (2000)
Genetics 155, 1055-1067
 |  Abstract »  |  Full Text »

Mechanism of Caffeine-Induced Checkpoint Override in Fission Yeast.

B. A. Moser, J.-M. Brondello, B. Baber-Furnari, and P. Russell (2000)
Mol. Cell. Biol. 20, 4288-4294
 |  Abstract »  |  Full Text »  |  PDF »

DNA Repair Protein Rad55 Is a Terminal Substrate of the DNA Damage Checkpoints.

V. I. Bashkirov, J. S. King, E. V. Bashkirova, J. Schmuckli-Maurer, and W.-D. Heyer (2000)
Mol. Cell. Biol. 20, 4393-4404
 |  Abstract »  |  Full Text »  |  PDF »

The Saccharomyces cerevisiae Centromere Protein Slk19p Is Required for Two Successive Divisions During Meiosis.

X. Zeng and W. S. Saunders (2000)
Genetics 155, 577-587
 |  Abstract »  |  Full Text »

EXO1 and MSH6 Are High-Copy Suppressors of Conditional Mutations in the MSH2 Mismatch Repair Gene of Saccharomyces cerevisiae.

T. Sokolsky and E. Alani (2000)
Genetics 155, 589-599
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Involvement of the PP2C-Like Phosphatase Ptc2p in the DNA Checkpoint Pathways of Saccharomyces cerevisiae.

M.-C. Marsolier, P. Roussel, C. Leroy, and C. Mann (2000)
Genetics 154, 1523-1532
 |  Abstract »  |  Full Text »

The Aspergillus nidulans uvsB Gene Encodes an ATM-Related Kinase Required for Multiple Facets of the DNA Damage Response.

A. F. Hofmann and S. D. Harris (2000)
Genetics 154, 1577-1586
 |  Abstract »  |  Full Text »

mus304 encodes a novel DNA damage checkpoint protein required during Drosophila development.

M. H. Brodsky, J. J. Sekelsky, G. Tsang, R. S. Hawley, and G. M. Rubin (2000)
Genes & Dev. 14, 666-678
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Mik1 levels accumulate in S phase and may mediate an intrinsic link between S phase and mitosis.

P. U. Christensen, N. J. Bentley, R. G. Martinho, O. Nielsen, and A. M. Carr (2000)
PNAS 97, 2579-2584
 |  Abstract »  |  Full Text »  |  PDF »

DNA Damage-Inducible and RAD52-Independent Repair of DNA Double-Strand Breaks in Saccharomyces cerevisiae.

C. W. Moore, J. McKoy, M. Dardalhon, D. Davermann, M. Martinez, and D. Averbeck (2000)
Genetics 154, 1085-1099
 |  Abstract »  |  Full Text »

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