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Science 24 June 1988:
Vol. 240. no. 4860, pp. 1774 - 1776
DOI: 10.1126/science.3381101
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Articles

Science, Vol 240, Issue 4860, 1774-1776
Copyright © 1988 by American Association for the Advancement of Science

articles

Hair cell regeneration after acoustic trauma in adult Coturnix quail

BM Ryals and EW Rubel

Audiology and Speech Pathology, Veterans Administration Medical Center, Richmond, VA 23249.

Recovery of hair cells was studied at various times after acoustic trauma in adult quail. An initial loss of hair cells recovered to within 5 percent of the original number of cells. Tritium-labeled thymidine was injected after this acoustic trauma to determine if mitosis played a role in recovery of hair cells. Within 10 days of acoustic trauma, incorporation of [3H]thymidine was seen over the nuclei of hair cells and supporting cells in the region of initial hair cell loss. Thus, hair cell regeneration can occur after embryonic terminal mitosis.


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