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Science 5 June 1987: Vol. 236. no. 4806, pp. 1245 - 1252 DOI: 10.1126/science.2884726
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Articles
Science, Vol 236, Issue 4806, 1245-1252
Copyright © 1987 by American Association for the Advancement of Science
Homeo boxes in the study of development
WJ Gehring
The body plan of Drosophila is determined to a large extent by homeotic genes, which specify the identity and spatial arrangement of the body segments. Homeotic genes share a characteristic DNA segment, the homeo box, which encodes a defined domain of the homeotic proteins. The homeo domain seems to mediate the binding to specific DNA sequences, whereby the homeotic proteins exert a gene regulatory function. By isolating the normal Antennapedia gene, fusing its protein-coding sequences to an inducible promoter, and reintroducing this fusion gene into the germline of flies, it has been possible to transform head structures into thoracic structures and to alter the body plan in a predicted way. Sequence homologies suggest that similar genetic mechanisms may control development in higher organisms.
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| Abstract »
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| Abstract »
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| Abstract »
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| Abstract »
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- M G Rosenfeld (1991)
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- G Lavorgna, H Ueda, J Clos, and C Wu (1991)
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| Abstract »
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- J D Allen, T Lints, N A Jenkins, N G Copeland, A Strasser, R P Harvey, and J M Adams (1991)
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| Abstract »
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| Abstract »
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| Abstract »
| PDF »
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| Abstract »
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- O H Sundin and G Eichele (1990)
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| Abstract »
| PDF »
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| Abstract »
| PDF »
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- M Peifer and E Wieschaus (1990)
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| Abstract »
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| Abstract »
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- D M Simmons, J W Voss, H A Ingraham, J M Holloway, R S Broide, M G Rosenfeld, and L W Swanson (1990)
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| Abstract »
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| Abstract »
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- A two-base change in a POU factor-binding site switches pituitary-specific to lymphoid-specific gene expression..
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| Abstract »
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- H J Mangalam, V R Albert, H A Ingraham, M Kapiloff, L Wilson, C Nelson, H Elsholtz, and M G Rosenfeld (1989)
Genes & Dev.
3, 946-958
| Abstract »
| PDF »
- Cell-specific expression of the prolactin gene in transgenic mice is controlled by synergistic interactions between promoter and enhancer elements..
- E B Crenshaw, K Kalla, D M Simmons, L W Swanson, and M G Rosenfeld (1989)
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3, 959-972
| Abstract »
| PDF »
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- L M Angerer, G J Dolecki, M L Gagnon, R Lum, G Wang, Q Yang, T Humphreys, and R C Angerer (1989)
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| Abstract »
| PDF »
- Purification of growth hormone-specific transcription factor GHF-1 containing homeobox.
- J. Castrillo, M Bodner, and M Karin (1989)
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243, 814-817
| Abstract »
| PDF »
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- W F Odenwald, J Garbern, H Arnheiter, E Tournier-Lasserve, and R A Lazzarini (1989)
Genes & Dev.
3, 158-172
| Abstract »
| PDF »
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- K Kornfeld, R B Saint, P A Beachy, P J Harte, D A Peattie, and D S Hogness (1989)
Genes & Dev.
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| Abstract »
| PDF »
- Peptide and protein synthesis by segment synthesis-condensation.
- E. Kaiser, H Mihara, G. Laforet, J. Kelly, L Walters, M. Findeis, and T Sasaki (1989)
Science
243, 187-192
| Abstract »
| PDF »
- A new family of mouse homeo box-containing genes: molecular structure, chromosomal location, and developmental expression of Hox-7.1..
- R E Hill, P F Jones, A R Rees, C M Sime, M J Justice, N G Copeland, N A Jenkins, E Graham, and D R Davidson (1989)
Genes & Dev.
3, 26-37
| Abstract »
| PDF »
- The B-cell-specific Oct-2 protein contains POU box- and homeo box-type domains..
- R G Clerc, L M Corcoran, J H LeBowitz, D Baltimore, and P A Sharp (1988)
Genes & Dev.
2, 1570-1581
| Abstract »
| PDF »
- A chemically synthesized Antennapedia homeo domain binds to a specific DNA sequence.
- H Mihara and E. Kaiser (1988)
Science
242, 925-927
| Abstract »
| PDF »
- Characterization of a murine homeo box gene, Hox-2.6, related to the Drosophila Deformed gene..
- A Graham, N Papalopulu, J Lorimer, J H McVey, E G Tuddenham, and R Krumlauf (1988)
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| Abstract »
| PDF »
- Expression of homeo box genes during mouse development: a review..
- P W Holland and B L Hogan (1988)
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- R T Sauer, D L Smith, and A D Johnson (1988)
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| Abstract »
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- G. Rubin (1988)
Science
240, 1453-1459
| Abstract »
| PDF »
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- C A Davis, S E Noble-Topham, J Rossant, and A L Joyner (1988)
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| Abstract »
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- D Bohmann, T. Bos, A Admon, T Nishimura, P. Vogt, and R Tjian (1987)
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| Abstract »
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