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Science 13 March 1987:
Vol. 235. no. 4794, pp. 1379 - 1382
DOI: 10.1126/science.2881353
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Articles

Science, Vol 235, Issue 4794, 1379-1382
Copyright © 1987 by American Association for the Advancement of Science

articles

Region-specific expression of two mouse homeo box genes

MF Utset, A Awgulewitsch, FH Ruddle, and W McGinnis

Mammalian homeo box genes have been identified on the basis of sequence homology to Drosophila homeotic and segmentation genes. These studies examine the distribution of transcripts from two mouse homeo box genes, Hox-2.1 and Hox-3.1, throughout the latter third of prenatal development. Transcripts from these genes are regionally localized along the rostro-caudal axis of the developing central nervous system, yielding expression patterns very similar to patterns of Drosophila homeotic gene expression.


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