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Science 10 October 1986:
Vol. 234. no. 4773, pp. 161 - 166
DOI: 10.1126/science.3018928

Articles

Science, Vol 234, Issue 4773, 161-166
Copyright © 1986 by American Association for the Advancement of Science


articles

Early signals in the mitogenic response

E Rozengurt

Polypeptide growth factors, regulatory peptides, and a variety of pharmacological agents acting alone or synergistically induce mitogenesis in cultured fibroblasts. The early signals in the membrane, cytosol, and nucleus promoted by these extracellular factors, together with their mitogenic effectiveness, are integrated in a unified hypothesis for the regulation of fibroblast growth.


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H. Weng, S.-Y. Choi, and D. V. Faller (1995)
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J Carmichael (1994)
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Role of Na+/H+ exchange by interferon-gamma in enhanced expression of JE and I-A beta genes.
V Prpic, S. Yu, F Figueiredo, P. Hollenbach, G Gawdi, B Herman, R. Uhing, and D. Adams (1989)
Science 244, 469-471
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Detection of the Cancer-Prone Colon, Using Transepithelial Impedance Analysis.
R. J. Davies, R. Joseph, H. Asbun, and M. Sedwitz (1989)
Arch Surg 124, 480-484
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Structure and function of human amphiregulin: a member of the epidermal growth factor family.
M Shoyab, G. Plowman, V. McDonald, J. Bradley, and G. Todaro (1989)
Science 243, 1074-1076
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Novel regulators of bone formation: molecular clones and activities.
J. Wozney, V Rosen, A. Celeste, L. Mitsock, M. Whitters, R. Kriz, R. Hewick, and E. Wang (1988)
Science 242, 1528-1534
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Potassium salt microinjection into Xenopus oocytes mimics gonadotropin treatment.
Y. Lau, R. Yassin, and S. Horowitz (1988)
Science 240, 1321-1323
   Abstract »    PDF »
The c-fos serum response element responds to protein kinase C-dependent and -independent signals but not to cyclic AMP..
M Z Gilman (1988)
Genes & Dev. 2, 394-402
   Abstract »    PDF »
Mitogenesis in response to PDGF and bombesin abolished by microinjection of antibody to PIP2.
K Matuoka, K Fukami, O Nakanishi, S Kawai, and T Takenawa (1988)
Science 239, 640-643
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Microinjection of the Catalytic Subunit of cAMP-dependent Protein Kinase Induces Expression of the c-fos Gene.
K.T. Riabowol, M.Z. Gilman, and J.R. Feramisco (1988)
Cold Spring Harb Symp Quant Biol 53, 85-90
   Abstract »    PDF »
Tyrosine Phosphorylation in Signal Transduction.
T.M. Roberts, D. Kaplan, W. Morgan, T. Keller, H. Mamon, H. Piwnica-Worms, B. Druker, B. Cohen, B. Schaffhausen, M. Whitman, et al. (1988)
Cold Spring Harb Symp Quant Biol 53, 161-171
   Abstract »    PDF »



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