Science 5 September 1986: Vol. 233. no. 4768, pp. 1089 - 1093 DOI: 10.1126/science.3016903

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Articles

Genetically Modified CD34+ Hematopoietic Stem Cells Contribute to Turnover of Brain Perivascular Macrophages in Long-Term Repopulated Primates.

C. Soulas, R. E. Donahue, C. E. Dunbar, D. A. Persons, X. Alvarez, and K. C. Williams (2009)
Am. J. Pathol. 174, 1808-1817
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1 Infection Increases the In Vivo Capacity of Peripheral Monocytes To Cross the Blood-Brain Barrier into the Brain and the In Vivo Sensitivity of the Blood-Brain Barrier to Disruption by Lipopolysaccharide.

H. Wang, J. Sun, and H. Goldstein (2008)
J. Virol. 82, 7591-7600
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 Tat Mediates Degradation of RON Receptor Tyrosine Kinase, a Regulator of Inflammation.

P. Kalantari, O. F. Harandi, P. A. Hankey, and A. J. Henderson (2008)
J. Immunol. 181, 1548-1555
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Response to Comment on "Transcription Factor FOXO3a Mediates Apoptosis in HIV-1-Infected Macrophages".

Y. Huang, M. Cui, N. Erdmann, A. A. Constantino, Y. Zhao, and J. Zheng (2008)
J. Immunol. 180, 7783-7784
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Transcription Factor FOXO3a Mediates Apoptosis in HIV-1-Infected Macrophages.

M. Cui, Y. Huang, Y. Zhao, and J. Zheng (2008)
J. Immunol. 180, 898-906
 |  Abstract »  |  Full Text »  |  PDF »

Although Macrophage-Tropic Simian/Human Immunodeficiency Viruses Can Exhibit a Range of Pathogenic Phenotypes, a Majority of Isolates Induce No Clinical Disease in Immunocompetent Macaques.

T. Igarashi, O. K. Donau, H. Imamichi, Y. Nishimura, T. S. Theodore, R. Iyengar, C. Erb, A. Buckler-White, C. E. Buckler, and M. A. Martin (2007)
J. Virol. 81, 10669-10679
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Comparative Study of Methods for Detecting Sequence Compartmentalization in Human Immunodeficiency Virus Type 1.

S. Zarate, S. L. K. Pond, P. Shapshak, and S. D. W. Frost (2007)
J. Virol. 81, 6643-6651
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HIV-1 specific CTLs effectively suppress replication of HIV-1 in HIV-1 infected macrophages.

M. Fujiwara and M. Takiguchi (2007)
Blood 109, 4832-4838
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Type 1: Resistance to Nucleoside Analogues and Replicative Capacity in Primary Human Macrophages.

D. Perez-Bercoff, S. Wurtzer, S. Compain, H. Benech, and F. Clavel (2007)
J. Virol. 81, 4540-4550
 |  Abstract »  |  Full Text »  |  PDF »

Administration of Fludarabine-Loaded Autologous Red Blood Cells in Simian Immunodeficiency Virus-Infected Sooty Mangabeys Depletes pSTAT-1-Expressing Macrophages and Delays the Rebound of Viremia after Suspension of Antiretroviral Therapy..

B. Cervasi, M. Paiardini, S. Serafini, A. Fraternale, M. Menotta, J. Engram, B. Lawson, S. I. Staprans, G. Piedimonte, C. F. Perno, et al. (2006)
J. Virol. 80, 10335-10345
 |  Abstract »  |  Full Text »  |  PDF »

In vitro modeling of the HIV-macrophage reservoir.

A. Brown, H. Zhang, P. Lopez, C. A. Pardo, and S. Gartner (2006)
J. Leukoc. Biol. 80, 1127-1135
 |  Abstract »  |  Full Text »  |  PDF »

Mechanisms underlying activity of antiretroviral drugs in HIV-1-infected macrophages: new therapeutic strategies.

S. Aquaro, V. Svicher, D. Schols, M. Pollicita, A. Antinori, J. Balzarini, and C. F. Perno (2006)
J. Leukoc. Biol. 80, 1103-1110
 |  Abstract »  |  Full Text »  |  PDF »

TRAIL-Mediated Apoptosis in HIV-1-Infected Macrophages Is Dependent on the Inhibition of Akt-1 Phosphorylation.

Y. Huang, N. Erdmann, H. Peng, S. Herek, J. S. Davis, X. Luo, T. Ikezu, and J. Zheng (2006)
J. Immunol. 177, 2304-2313
 |  Abstract »  |  Full Text »  |  PDF »

Thinning of the cerebral cortex visualized in HIV/AIDS reflects CD4+ T lymphocyte decline.

P. M. Thompson, R. A. Dutton, K. M. Hayashi, A. W. Toga, O. L. Lopez, H. J. Aizenstein, and J. T. Becker (2005)
PNAS 102, 15647-15652
 |  Abstract »  |  Full Text »  |  PDF »

Human immunodeficiency virus 1 (HIV-1) envelope-dependent cell-cell fusion modulation by HIV-positive sera is related to disease progression.

L. Huerta, G. Gomez-Icazbalceta, L. Soto-Ramirez, M. Viveros-Rogel, R. Rodriguez, L. Fuentes, E. Lamoyi, and C. Larralde (2005)
J. Gen. Virol. 86, 1961-1966
 |  Abstract »  |  Full Text »  |  PDF »

Compartmentalized Human Immunodeficiency Virus Type 1 Present in Cerebrospinal Fluid Is Produced by Short-Lived Cells.

P. R. Harrington, D. W. Haas, K. Ritola, and R. Swanstrom (2005)
J. Virol. 79, 7959-7966
 |  Abstract »  |  Full Text »  |  PDF »

Limited development and progression of resistance of HIV-1 to the nucleoside analogue reverse transcriptase inhibitor lamivudine in human primary macrophages.

S. Aquaro, V. Svicher, F. Ceccherini-Silberstein, A. Cenci, F. Marcuccilli, S. Giannella, L. Marcon, R. Calio, J. Balzarini, and C.-F. Perno (2005)
J. Antimicrob. Chemother. 55, 872-878
 |  Abstract »  |  Full Text »  |  PDF »

Roles for CXC Chemokine Ligands 10 and 11 in Recruiting CD4+ T Cells to HIV-1-Infected Monocyte-Derived Macrophages, Dendritic Cells, and Lymph Nodes.

J. F. Foley, C.-R. Yu, R. Solow, M. Yacobucci, K. W. C. Peden, and J. M. Farber (2005)
J. Immunol. 174, 4892-4900
 |  Abstract »  |  Full Text »  |  PDF »

Genetic Composition of Human Immunodeficiency Virus Type 1 in Cerebrospinal Fluid and Blood without Treatment and during Failing Antiretroviral Therapy.

M. C. Strain, S. Letendre, S. K. Pillai, T. Russell, C. C. Ignacio, H. F. Gunthard, B. Good, D. M. Smith, S. M. Wolinsky, M. Furtado, et al. (2005)
J. Virol. 79, 1772-1788
 |  Abstract »  |  Full Text »  |  PDF »

RON Receptor Tyrosine Kinase, a Negative Regulator of Inflammation, Inhibits HIV-1 Transcription in Monocytes/Macrophages and Is Decreased in Brain Tissue from Patients with AIDS.

E. S. Lee, P. Kalantari, S. Tsutsui{section}, A. Klatt, J. Holden, P. H. Correll, C. Power{section}, and A. J. Henderson (2004)
J. Immunol. 173, 6864-6872
 |  Abstract »  |  Full Text »  |  PDF »

Role of Microglia in Central Nervous System Infections.

R. B. Rock, G. Gekker, S. Hu, W. S. Sheng, M. Cheeran, J. R. Lokensgard, and P. K. Peterson (2004)
Clin. Microbiol. Rev. 17, 942-964
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Biological Analysis of Human Immunodeficiency Virus Type 1 R5 Envelopes Amplified from Brain and Lymph Node Tissues of AIDS Patients with Neuropathology Reveals Two Distinct Tropism Phenotypes and Identifies Envelopes in the Brain That Confer an Enhanced Tropism and Fusigenicity for Macrophages.

P. J. Peters, J. Bhattacharya, S. Hibbitts, M. T. Dittmar, G. Simmons, J. Bell, P. Simmonds, and P. R. Clapham (2004)
J. Virol. 78, 6915-6926
 |  Abstract »  |  Full Text »  |  PDF »

Characterization of Restrictions to Human Immunodeficiency Virus Type 1 Infection of Monocytes.

K. Triques and M. Stevenson (2004)
J. Virol. 78, 5523-5527
 |  Abstract »  |  Full Text »  |  PDF »

Where Does HIV Live?.

J. Stebbing, B. Gazzard, and D. C. Douek (2004)
N. Engl. J. Med. 350, 1872-1880
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Cell-Type-Dependent Targeting of Human Immunodeficiency Virus Type 1 Assembly to the Plasma Membrane and the Multivesicular Body.

A. Ono and E. O. Freed (2004)
J. Virol. 78, 1552-1563
 |  Abstract »  |  Full Text »  |  PDF »

Macrophage-Tropic Simian/Human Immunodeficiency Virus Chimeras Use CXCR4, Not CCR5, for Infections of Rhesus Macaque Peripheral Blood Mononuclear Cells and Alveolar Macrophages.

T. Igarashi, O. K. Donau, H. Imamichi, M.-J. Dumaurier, R. Sadjadpour, R. J. Plishka, A. Buckler-White, C. Buckler, A. F. Suffredini, H. C. Lane, et al. (2003)
J. Virol. 77, 13042-13052
 |  Abstract »  |  Full Text »  |  PDF »

Mononuclear phagocyte immunity and the neuropathogenesis of HIV-1 infection.

Y. Persidsky and H. E. Gendelman (2003)
J. Leukoc. Biol. 74, 691-701
 |  Abstract »  |  Full Text »  |  PDF »

The emergence and characterization of macrophage-tropic SIV/HIV chimeric viruses (SHIVs) present in CD4+ T cell-depleted rhesus monkeys.

T. Igarashi, H. Imamichi, C. R. Brown, V. M. Hirsch, and M. A. Martin (2003)
J. Leukoc. Biol. 74, 772-780
 |  Abstract »  |  Full Text »  |  PDF »

Oligodendrocyte-Specific Expression of Human Immunodeficiency Virus Type 1 Nef in Transgenic Mice Leads to Vacuolar Myelopathy and Alters Oligodendrocyte Phenotype In Vitro.

F. Radja, D. G. Kay, S. Albrecht, and P. Jolicoeur (2003)
J. Virol. 77, 11745-11753
 |  Abstract »  |  Full Text »  |  PDF »

Viral and host cofactors facilitate HIV-1 replication in macrophages.

S. M. Wahl, T. Greenwell-Wild, G. Peng, G. Ma, J. M. Orenstein, and N. Vazquez (2003)
J. Leukoc. Biol. 74, 726-735
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Tumor necrosis factor-related apoptosis-inducing ligand induces neuronal death in a murine model of HIV central nervous system infection.

Y. Miura, N. Misawa, Y. Kawano, H. Okada, Y. Inagaki, N. Yamamoto, M. Ito, H. Yagita, K. Okumura, H. Mizusawa, et al. (2003)
PNAS 100, 2777-2782
 |  Abstract »  |  Full Text »  |  PDF »

Induction of Apoptosis by HIV-1-Infected Monocytic Cells.

K. Sperber, P. Beuria, N. Singha, I. Gelman, P. Cortes, H. Chen, and T. Kraus (2003)
J. Immunol. 170, 1566-1578
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The HIV-1 Nef Protein and Phagocyte NADPH Oxidase Activation.

F. Vilhardt, O. Plastre, M. Sawada, K. Suzuki, M. Wiznerowicz, E. Kiyokawa, D. Trono, and K.-H. Krause (2002)
J. Biol. Chem. 277, 42136-42143
 |  Abstract »  |  Full Text »  |  PDF »

From the Cover: HIV-1 infection and AIDS dementia are influenced by a mutant MCP-1 allele linked to increased monocyte infiltration of tissues and MCP-1 levels.

E. Gonzalez, B. H. Rovin, L. Sen, G. Cooke, R. Dhanda, S. Mummidi, H. Kulkarni, M. J. Bamshad, V. Telles, S. A. Anderson, et al. (2002)
PNAS 99, 13795-13800
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Amino acid deletions are introduced into the V2 region of gp120 during independent pathogenic simian immunodeficiency virus/HIV chimeric virus (SHIV) infections of rhesus monkeys generating variants that are macrophage tropic.

H. Imamichi, T. Igarashi, T. Imamichi, O. K. Donau, Y. Endo, Y. Nishimura, R. L. Willey, A. F. Suffredini, H. C. Lane, and M. A. Martin (2002)
PNAS 99, 13813-13818
 |  Abstract »  |  Full Text »  |  PDF »

Neuropathogenesis of Lentiviral Infection in Macaques : Roles of CXCR4 and CCR5 Viruses and Interleukin-4 in Enhancing Monocyte Chemoattractant Protein-1 Production in Macrophages.

A. Hicks, R. Potula, Y. J. Sui, F. Villinger, D. Pinson, I. Adany, Z. Li, C. Long, P. Cheney, J. Marcario, et al. (2002)
Am. J. Pathol. 161, 813-822
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of CXCR4-Tropic HIV-1 Infection by Lipopolysaccharide: Evidence of Different Mechanisms in Macrophages and T Lymphocytes.

A. Verani, F. Sironi, A. G. Siccardi, P. Lusso, and D. Vercelli (2002)
J. Immunol. 168, 6388-6395
 |  Abstract »  |  Full Text »  |  PDF »

Interferon-{alpha} as an immunotherapeutic protein.

D. L. Brassard, M. J. Grace, and R. W. Bordens (2002)
J. Leukoc. Biol. 71, 565-581
 |  Abstract »  |  Full Text »  |  PDF »

Progress Toward a Human CD4/CCR5 Transgenic Rat Model for De Novo Infection by Human Immunodeficiency Virus Type 1.

O. T. Keppler, F. J. Welte, T. A. Ngo, P. S. Chin, K. S. Patton, C.-L. Tsou, N. W. Abbey, M. E. Sharkey, R. M. Grant, Y. You, et al. (2002)
J. Exp. Med. 195, 719-736
 |  Abstract »  |  Full Text »  |  PDF »

Evidence for Human Immunodeficiency Virus Type 1 Replication In Vivo in CD14+ Monocytes and Its Potential Role as a Source of Virus in Patients on Highly Active Antiretroviral Therapy.

T. Zhu, D. Muthui, S. Holte, D. Nickle, F. Feng, S. Brodie, Y. Hwangbo, J. I. Mullins, and L. Corey (2002)
J. Virol. 76, 707-716
 |  Abstract »  |  Full Text »  |  PDF »

Directed Egress of Animal Viruses Promotes Cell-to-Cell Spread.

D. C. Johnson and M. T. Huber (2002)
J. Virol. 76, 1-8
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The contribution of oxidative stress in apoptosis of human-cultured astroglial cells induced by supernatants of HIV-1-infected macrophages.

V. Mollace, D. Salvemini, D. P. Riley, C. Muscoli, M. Iannone, T. Granato, L. Masuelli, A. Modesti, D. Rotiroti, R. Nistico, et al. (2002)
J. Leukoc. Biol. 71, 65-72
 |  Abstract »  |  Full Text »  |  PDF »

NF-kappa B cis-Acting Motifs of the Human Immunodeficiency Virus (HIV) Long Terminal Repeat Regulate HIV Transcription in Human Macrophages.

S. Asin, G. D. Bren, E. M. Carmona, N. J. Solan, and C. V. Paya (2001)
J. Virol. 75, 11408-11416
 |  Abstract »  |  Full Text »  |  PDF »

Endothelial Cells Enhance Human Immunodeficiency Virus Type 1 Replication in Macrophages through a C/EBP-Dependent Mechanism.

E. S. Lee, H. Zhou, and A. J. Henderson (2001)
J. Virol. 75, 9703-9712
 |  Abstract »  |  Full Text »  |  PDF »

Syndecans Serve as Attachment Receptors for Human Immunodeficiency Virus Type 1 on Macrophages.

A. C. S. Saphire, M. D. Bobardt, Z. Zhang, G. David, and P. A. Gallay (2001)
J. Virol. 75, 9187-9200
 |  Abstract »  |  Full Text »  |  PDF »

Highly Productive Infection with Pseudotyped Human Immunodeficiency Virus Type 1 (HIV-1) Indicates No Intracellular Restrictions to HIV-1 Replication in Primary Human Astrocytes.

M. Canki, J. N. F. Thai, W. Chao, A. Ghorpade, M. J. Potash, and D. J. Volsky (2001)
J. Virol. 75, 7925-7933
 |  Abstract »  |  Full Text »  |  PDF »

Susceptibility of Rat-Derived Cells to Replication by Human Immunodeficiency Virus Type 1.

O. T. Keppler, W. Yonemoto, F. J. Welte, K. S. Patton, D. Iacovides, R. E. Atchison, T. Ngo, D. L. Hirschberg, R. F. Speck, and M. A. Goldsmith (2001)
J. Virol. 75, 8063-8073
 |  Abstract »  |  Full Text »  |  PDF »

Erythrocyte-mediated delivery of a new homodinucleotide active against human immunodeficiency virus and herpes simplex virus.

L. Rossi, S. Serafini, L. Cappellacci, E. Balestra, G. Brandi, G. F. Schiavano, P. Franchetti, M. Grifantini, C.-F. Perno, and M. Magnani (2001)
J. Antimicrob. Chemother. 47, 819-827
 |  Abstract »  |  Full Text »  |  PDF »

Regulation of Human Immunodeficiency Virus Type 1 Infection, {beta}-Chemokine Production, and CCR5 Expression in CD40L-Stimulated Macrophages: Immune Control of Viral Entry.

R. L. Cotter, J. Zheng, M. Che, D. Niemann, Y. Liu, J. He, E. Thomas, and H. E. Gendelman (2001)
J. Virol. 75, 4308-4320
 |  Abstract »  |  Full Text »  |  PDF »

The LD78{beta} Isoform of MIP-1{alpha} Is the Most Potent CC-Chemokine in Inhibiting CCR5-Dependent Human Immunodeficiency Virus Type 1 Replication in Human Macrophages.

S. Aquaro, P. Menten, S. Struyf, P. Proost, J. Van Damme, E. De Clercq, and D. Schols (2001)
J. Virol. 75, 4402-4406
 |  Abstract »  |  Full Text »  |  PDF »

Perivascular Macrophages Are the Primary Cell Type Productively Infected by Simian Immunodeficiency Virus in the Brains of Macaques: Implications for the Neuropathogenesis of AIDS.

K. C. Williams, S. Corey, S. V. Westmoreland, D. Pauley, H. Knight, C. deBakker, X. Alvarez, and A. A. Lackner (2001)
J. Exp. Med. 193, 905-916
 |  Abstract »  |  Full Text »  |  PDF »

Differential CD4/CCR5 Utilization, gp120 Conformation, and Neutralization Sensitivity between Envelopes from a Microglia-Adapted Human Immunodeficiency Virus Type 1 and Its Parental Isolate.

J. Martin, C. C. LaBranche, and F. Gonzalez-Scarano (2001)
J. Virol. 75, 3568-3580
 |  Abstract »  |  Full Text »  |  PDF »

Investigation of the simian polyomavirus SV40 as a potential causative agent of human neurological disorders in AIDS patients.

M. TOGNON, F. MARTINI, L. IACCHERI, R. CULTRERA, and C. CONTINI (2001)
J. Med. Microbiol. 50, 165-172
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 Tat promotes monocyte chemoattractant protein-1 secretion followed by transmigration of monocytes.

I.-W. Park, J.-F. Wang, and J. E. Groopman (2001)
Blood 97, 352-358
 |  Abstract »  |  Full Text »  |  PDF »

T-tropic human immunodeficiency virus (HIV) type 1 Nef protein enters human monocyte-macrophages and induces resistance to HIV replication: a possible mechanism of HIV T-tropic emergence in AIDS.

L. Alessandrini, A. C. Santarcangelo, E. Olivetta, F. Ferrantelli, P. d’Aloja, K. Pugliese, E. Pelosi, C. Chelucci, G. Mattia, C. Peschle, et al. (2000)
J. Gen. Virol. 81, 2905-2917
 |  Abstract »  |  Full Text »

Mechanisms for Adaptation of Simian Immunodeficiency Virus to Replication in Alveolar Macrophages.

K. Mori, M. Rosenzweig, and R. C. Desrosiers (2000)
J. Virol. 74, 10852-10859
 |  Abstract »  |  Full Text »  |  PDF »

Nitric Oxide Synthesis Enhances Human Immunodeficiency Virus Replication in Primary Human Macrophages.

D. Blond, H. Raoul, R. Le Grand, and D. Dormont (2000)
J. Virol. 74, 8904-8912
 |  Abstract »  |  Full Text »  |  PDF »

Induction of the Chemokines Interleukin-8 and IP-10 by Human Immunodeficiency Virus Type 1 Tat in Astrocytes.

O. Kutsch, J.-W. Oh, A. Nath, and E. N. Benveniste (2000)
J. Virol. 74, 9214-9221
 |  Abstract »  |  Full Text »  |  PDF »

Mononuclear phagocytes mediate blood-brain barrier compromise and neuronal injury during HIV-1-associated dementia.

Y. Persidsky, J. Zheng, D. Miller, and H. E. Gendelman (2000)
J. Leukoc. Biol. 68, 413-422
 |  Abstract »  |  Full Text »  |  PDF »

Primary macrophages infected by human immunodeficiency virus trigger CD95-mediated apoptosis of uninfected astrocytes.

S. Aquaro, S. Panti, M. C. Caroleo, E. Balestra, A. Cenci, F. Forbici, G. Ippolito, A. Mastino, R. Testi, V. Mollace, et al. (2000)
J. Leukoc. Biol. 68, 429-435
 |  Abstract »  |  Full Text »  |  PDF »

Lentivirus Infection in the Brain Induces Matrix Metalloproteinase Expression: Role of Envelope Diversity.

J. B. Johnston, Y. Jiang, G. van Marle, M. B. Mayne, W. Ni, J. Holden, J. C. McArthur, and C. Power (2000)
J. Virol. 74, 7211-7220
 |  Abstract »  |  Full Text »  |  PDF »

Inhibition of Human Immunodeficiency Virus Type 1 Replication in Primary CD4+ T Lymphocytes, Monocytes, and Dendritic Cells by Cytotoxic T Lymphocytes.

M. E. Severino, N. V. Sipsas, P. T. Nguyen, S. A. Kalams, B. D. Walker, R. P. Johnson, and O. O. Yang (2000)
J. Virol. 74, 6695-6699
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus (HIV)-Positive Sera Obtained Shortly after Seroconversion Neutralize Autologous HIV Type 1 Isolates on Primary Macrophages but Not on Lymphocytes.

H. Ruppach, P. Nara, I. Raudonat, Z. Elanjikal, H. Rubsamen-Waigmann, and U. Dietrich (2000)
J. Virol. 74, 5403-5411
 |  Abstract »  |  Full Text »  |  PDF »

Identification of Critical Amino Acid Residues in Human Immunodeficiency Virus Type 1 IN Required for Efficient Proviral DNA Formation at Steps prior to Integration in Dividing and Nondividing Cells.

N. Tsurutani, M. Kubo, Y. Maeda, T. Ohashi, N. Yamamoto, M. Kannagi, and T. Masuda (2000)
J. Virol. 74, 4795-4806
 |  Abstract »  |  Full Text »  |  PDF »

Lipopolysaccharide Inhibits HIV-1 Infection of Monocyte- Derived Macrophages Through Direct and Sustained Down-Regulation of CC Chemokine Receptor 5.

G. Franchin, G. Zybarth, W. W. Dai, L. Dubrovsky, N. Reiling, H. Schmidtmayerova, M. Bukrinsky, and B. Sherry (2000)
J. Immunol. 164, 2592-2601
 |  Abstract »  |  Full Text »  |  PDF »

Abundant Defective Viral Particles Budding from Microglia in the Course of Retroviral Spongiform Encephalopathy.

R. Hansen, S. Czub, E. Werder, J. Herold, G. Gosztonyi, H. Gelderblom, S. Schimmer, S. Mazgareanu, V. ter Meulen, and M. Czub (2000)
J. Virol. 74, 1775-1780
 |  Abstract »  |  Full Text »  |  PDF »

Activities of Masked 2',3'-Dideoxynucleoside Monophosphate Derivatives against Human Immunodeficiency Virus in Resting Macrophages.

S. Aquaro, O. Wedgwood, C. Yarnold, D. Cahard, R. Pathinara, C. McGuigan, R. Calio', E. de Clercq, J. Balzarini, and C. F. Perno (2000)
Antimicrob. Agents Chemother. 44, 173-177
 |  Abstract »  |  Full Text »  |  PDF »

Activation of the PAK-Related Kinase by Human Immunodeficiency Virus Type 1 Nef in Primary Human Peripheral Blood Lymphocytes and Macrophages Leads to Phosphorylation of a PIX-p95 Complex.

A. Brown, X. Wang, E. Sawai, and C. Cheng-Mayer (1999)
J. Virol. 73, 9899-9907
 |  Abstract »  |  Full Text »  |  PDF »

Blood-Brain Barrier Tight Junction Disruption in Human Immunodeficiency Virus-1 Encephalitis.

L. M. Dallasta, L. A. Pisarov, J. E. Esplen, J. V. Werley, A. V. Moses, J. A. Nelson, and C. L. Achim (1999)
Am. J. Pathol. 155, 1915-1927
 |  Abstract »  |  Full Text »  |  PDF »

Nerve growth factor is an autocrine factor essential for the survival of macrophages infected with HIV.

E. Garaci, M. C. Caroleo, L. Aloe, S. Aquaro, M. Piacentini, N. Costa, A. Amendola, A. Micera, R. Calio, C.-F. Perno, et al. (1999)
PNAS 96, 14013-14018
 |  Abstract »  |  Full Text »  |  PDF »

Microglial and Astrocyte Chemokines Regulate Monocyte Migration through the Blood-Brain Barrier in Human Immunodeficiency Virus-1 Encephalitis.

Y. Persidsky, A. Ghorpade, J. Rasmussen, J. Limoges, X. J. Liu, M. Stins, M. Fiala, D. Way, K. S. Kim, M. H. Witte, et al. (1999)
Am. J. Pathol. 155, 1599-1611
 |  Abstract »  |  Full Text »  |  PDF »

Infection of HIV-1 Transgenic Mice with Mycobacterium avium Induces the Expression of Infectious Virus Selectively from a Mac-1-Positive Host Cell Population.

T. M. Doherty, C. Chougnet, M. Schito, B. K. Patterson, C. Fox, G. M. Shearer, G. Englund, and A. Sher (1999)
J. Immunol. 163, 1506-1515
 |  Abstract »  |  Full Text »  |  PDF »

Randomized trial of the platelet-activating factor antagonist lexipafant in HIV-associated cognitive impairment.

G. Schifitto, N. Sacktor, K. Marder, M. P. McDermott, J. C. McArthur, K. Kieburtz, S. Small, and L. G. Epstein (1999)
Neurology 53, 391
 |  Abstract »  |  Full Text »  |  PDF »

Inflammatory Cytokines and HIV-1-Associated Neurodegeneration: Oncostatin-M Produced by Mononuclear Cells from HIV-1-Infected Individuals Induces Apoptosis of Primary Neurons.

F. Ensoli, V. Fiorelli, M. DeCristofaro, D. Santini Muratori, A. Novi, B. Vannelli, C. J. Thiele, G. Luzi, and F. Aiuti (1999)
J. Immunol. 162, 6268-6277
 |  Abstract »  |  Full Text »  |  PDF »

Increased Peroxynitrite Activity in AIDS Dementia Complex: Implications for the Neuropathogenesis of HIV-1 Infection.

L. A. Boven, L. Gomes, C. Hery, F. Gray, J. Verhoef, P. Portegies, M. Tardieu, and H. S. L. M. Nottet (1999)
J. Immunol. 162, 4319-4327
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus-1-Infected Macrophages Induce Inducible Nitric Oxide Synthase and Nitric Oxide (NO) Production in Astrocytes: Astrocytic NO as a Possible Mediator of Neural Damage in Acquired Immunodeficiency Syndrome.

K. Hori, P. R. Burd, K. Furuke, J. Kutza, K. A. Weih, and K. A. Clouse (1999)
Blood 93, 1843-1850
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Replication Induces Monocyte Chemotactic Protein-1 in Human Macrophages and U937 Promonocytic Cells.

M. Mengozzi, C. De Filippi, P. Transidico, P. Biswas, M. Cota, S. Ghezzi, E. Vicenzi, A. Mantovani, S. Sozzani, and G. Poli (1999)
Blood 93, 1851-1857
 |  Abstract »  |  Full Text »  |  PDF »

V3 Recombinants Indicate a Central Role for CCR5 as a Coreceptor in Tissue Infection by Human Immunodeficiency Virus Type 1.

S. Y. Chan, R. F. Speck, C. Power, S. L. Gaffen, B. Chesebro, and M. A. Goldsmith (1999)
J. Virol. 73, 2350-2358
 |  Abstract »  |  Full Text »  |  PDF »

Neuronal Death Induced by Brain-Derived Human Immunodeficiency Virus Type 1 Envelope Genes Differs between Demented and Nondemented AIDS Patients.

C. Power, J. C. McArthur, A. Nath, K. Wehrly, M. Mayne, J. Nishio, T. Langelier, R. T. Johnson, and B. Chesebro (1998)
J. Virol. 72, 9045-9053
 |  Abstract »  |  Full Text »  |  PDF »

A phase I/II trial of nimodipine for HIV-related neurologic complications.

B. A. Navia, U. Dafni, D. Simpson, T. Tucker, E. Singer, J. C. McArthur, C. Yiannoutsos, L. Zaborski, S. A. Lipton, and the AIDS Clinical Trial Group* (1998)
Neurology 51, 221-228
 |  Abstract »  |  Full Text »  |  PDF »

HIV-1 Tat Elongates the G1 Phase and Indirectly Promotes HIV-1 Gene Expression in Cells of Glial Origin.

M. Kundu, S. Sharma, A. De Luca, A. Giordano, J. Rappaport, K. Khalili, and S. Amini (1998)
J. Biol. Chem. 273, 8130-8136
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus Neurotropism: an Analysis of Viral Replication and Cytopathicity for Divergent Strains in Monocytes and Microglia.

A. Ghorpade, A. Nukuna, M. Che, S. Haggerty, Y. Persidsky, E. Carter, L. Carhart, L. Shafer, and H. E. Gendelman (1998)
J. Virol. 72, 3340-3350
 |  Abstract »  |  Full Text »  |  PDF »

Differentiation of Promonocytic U937 Subclones into Macrophagelike Phenotypes Regulates a Cellular Factor(s) Which Modulates Fusion/Entry of Macrophagetropic Human Immunodeficiency Virus Type 1.

H. Moriuchi, M. Moriuchi, and A. S. Fauci (1998)
J. Virol. 72, 3394-3400
 |  Abstract »  |  Full Text »  |  PDF »

Induction of monocyte chemoattractant protein-1 in HIV-1 Tat-stimulated astrocytes and elevation in AIDS dementia.

K. Conant, A. Garzino-Demo, A. Nath, J. C. McArthur, W. Halliday, C. Power, R. C. Gallo, and E. O. Major (1998)
PNAS 95, 3117-3121
 |  Abstract »  |  Full Text »  |  PDF »

Differential Tropism and Chemokine Receptor Expression of Human Immunodeficiency Virus Type 1 in Neonatal Monocytes, Monocyte-Derived Macrophages, and Placental Macrophages.

W. R. Fear, A. M. Kesson, H. Naif, G. W. Lynch, and A. L. Cunningham (1998)
J. Virol. 72, 1334-1344
 |  Abstract »  |  Full Text »  |  PDF »

Use of Murine CXCR-4 as a Second Receptor by Some T-Cell-Tropic Human Immunodeficiency Viruses.

C. Parolin, A. Borsetti, H. Choe, M. Farzan, P. Kolchinsky, M. Heesen, Q. Ma, C. Gerard, G. Palu, M. E. Dorf, et al. (1998)
J. Virol. 72, 1652-1656
 |  Abstract »  |  Full Text »  |  PDF »

Human Immunodeficiency Virus-1 env Impairs Fcgamma Receptor-Mediated Phagocytosis Via a Cyclic Adenosine Monophosphate-Dependent Mechanism.

C. A. Thomas, O. K. Weinberger, B. L. Ziegler, S. Greenberg, I. Schieren, S. C. Silverstein, and J. El Khoury (1997)
Blood 90, 3760-3765
 |  Abstract »  |  Full Text »  |  PDF »

Two Orphan Seven-Transmembrane Segment Receptors Which Are Expressed in CD4-positive Cells Support Simian Immunodeficiency Virus Infection.

M. Farzan, H. Choe, K. Martin, L. Marcon, W. Hofmann, G. Karlsson, Y. Sun, P. Barrett, N. Marchand, N. Sullivan, et al. (1997)
J. Exp. Med. 186, 405-411
 |  Abstract »  |  Full Text »  |  PDF »

C-C Chemokines Released by Lipopolysaccharide (LPS)-stimulated Human Macrophages Suppress HIV-1 Infection in Both Macrophages and T Cells.

A. Verani, G. Scarlatti, M. Comar, E. Tresoldi, S. Polo, M. Giacca, P. Lusso, A. G. Siccardi, and D. Vercelli (1997)
J. Exp. Med. 185, 805-816
 |  Abstract »  |  Full Text »  |  PDF »

CD8+ T-cell-derived soluble factor(s), but not beta -chemokines RANTES, MIP-1alpha , and MIP-1beta , suppress HIV-1 replication in monocyte/macrophages.

H. Moriuchi, M. Moriuchi, C. Combadiere, P. M. Murphy, and A. S. Fauci (1996)
PNAS 93, 15341-15345
 |  Abstract »  |  Full Text »  |  PDF »

Serum Neopterin Level Predicts HIV-Related Mortality but Not Progression to AIDS or Development of Neurological Disease in Gay Men and Parenteral Drug Users.

N. Sacktor, X. Liu, M. Popescu, K. Marder, Y. Stern, and R. Mayeux (1995)
Arch Neurol 52, 676-679
 |  Abstract »  |  PDF »

Cerebral Single-photon Emission Computed Tomography Abnormalities in Human Immunodeficiency Virus Type 1-Infected Gay Men Without Cognitive Impairment.

N. Sacktor, I. Prohovnik, R. L. Van Heertum, G. Dooneief, J. Gorman, K. Marder, G. Todak, Y. Stern, and R. Mayeux (1995)
Arch Neurol 52, 607-611
 |  Abstract »  |  PDF »

Dementia Associated with the Acquired Immunodeficiency Syndrome.

S. A. Lipton and H. E. Gendelman (1995)
N. Engl. J. Med. 332, 934-940
 |  Full Text »  |  PDF »

Hydroxyurea as an inhibitor of human immunodeficiency virus-type 1 replication.

F Lori, A Malykh, A Cara, D Sun, J. Weinstein, J Lisziewicz, and R. Gallo (1994)
Science 266, 801-805
 |  Abstract »  |  PDF »

Magnetic Resonance Imaging Morphometric Analysis of Cerebral Volume Loss in Human Immunodeficiency Virus Infection.

T. L. Jernigan, S. Archibald, J. R. Hesselink, J. H. Atkinson, R. A. Velin, J. A. McCutchan, J. Chandler, I. Grant, and HNRC Group (1993)
Arch Neurol 50, 250-255
 |  Abstract »  |  PDF »

HIV-induced syncytia of a T cell line form single giant pseudopods and are motile.

A Sylwester, D Wessels, S. Anderson, R. Warren, D. Shutt, R. Kennedy, and D. Soll (1993)
J. Cell Sci. 106, 941-953
 |  Abstract »  |  PDF »

Expression directed from HIV long terminal repeats in the central nervous system of transgenic mice.

Corboy JR, J. Buzy, M. Zink, and J. Clements (1992)
Science 258, 1804-1808
 |  Abstract »  |  PDF »

Topical Review Article: The Neuropathology of Pediatric Acquired Immunodeficiency Syndrome.

D. K. Burns (1992)
J Child Neurol 7, 332-346
 |  Abstract »  |  PDF »

Inhibition of entry of HIV-1 in neural cell lines by antibodies against galactosyl ceramide.

J. Harouse, S Bhat, S. Spitalnik, M Laughlin, K Stefano, D. Silberberg, and F Gonzalez-Scarano (1991)
Science 253, 320-323
 |  Abstract »  |  PDF »

Identification of the envelope V3 loop as the primary determinant of cell tropism in HIV-1.

S. Hwang, T. Boyle, H. Lyerly, and B. Cullen (1991)
Science 253, 71-74
 |  Abstract »  |  PDF »

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