Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 24 January 1986:
Vol. 231. no. 4736, pp. 393 - 395
DOI: 10.1126/science.3510456
Prev | Table of Contents | Next

Articles

Science, Vol 231, Issue 4736, 393-395
Copyright © 1986 by American Association for the Advancement of Science

articles

The context effect does not require a fourth base pair

D Ayer and M Yarus

The translational activity of a transfer RNA at a codon varies at different message sites, although the codon does not vary. The source of this effect, which may help to determine the level of gene expression, is generally agreed to be in nearby message sequences. By making every possible nucleotide combination between position 33 of the transfer RNA and the major context nucleotide of the message, it was shown that base-pairing between the two nucleotides is not the source of this context effect on translation in vivo.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Translational recoding signals between gag and pol in diverse LTR retrotransposons.
X. GAO, E. R. HAVECKER, P. V. BARANOV, J. F. ATKINS, and D. F. VOYTAS (2003)
RNA 9, 1422-1430
   Abstract »    Full Text »    PDF »
Predominance of six different hexanucleotide recoding signals 3' of read-through stop codons.
L. Harrell, U. Melcher, and J. F. Atkins (2002)
Nucleic Acids Res. 30, 2011-2017
   Abstract »    Full Text »    PDF »
Reading frame selection and transfer RNA anticodon loop stacking.
J. Curran and M Yarus (1987)
Science 238, 1545-1550
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)