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Science 16 August 1985:
Vol. 229. no. 4714, pp. 673 - 675
DOI: 10.1126/science.3860952

Articles

Science, Vol 229, Issue 4714, 673-675
Copyright © 1985 by American Association for the Advancement of Science


articles

Physiological effects of transforming growth factor in the newborn mouse

JP Tam

Transforming growth factor-type alpha accelerated incisor eruption and eyelid opening in the newborn mouse and also retarded the growth rates of hair and body weight when administered in high dosage (0.7 to 4 micrograms per gram of body weight). The results of whole animal studies indicate that transforming growth factor-type alpha and epidermal growth factor do not differ significantly in these effects and suggest that transforming growth factor-type alpha may be important in immature animals.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Critical Reviews in Oral Biology & Medicine 13, 323-335
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Growth and Development in Rats Given Recombinant Human Epidermal Growth Factor1-48 as Neonates.
J. W. Henck, J. F. Reindel, and J. A. Anderson (2001)
Toxicol. Sci. 62, 80-91
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Role of Hormones in Pilosebaceous Unit Development.
D. Deplewski and R. L. Rosenfield (2000)
Endocr. Rev. 21, 363-392
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Cell Proliferation and Expression of EGF, TGF-{alpha}, and EGF Receptor in the Developing Primary Palate.
A. Iamaroon, B. Tait, and V.M. Diewert (1996)
Journal of Dental Research 75, 1534-1539
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Emergence of salivary gland cell lineage diversity suggests a role for androgen-independent epidermal growth factor receptor signaling.
E. Durban, P. Nagpala, P. Barreto, and E Durban (1995)
J. Cell Sci. 108, 2205-2212
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The mouse waved-2 phenotype results from a point mutation in the EGF receptor tyrosine kinase..
N C Luetteke, H K Phillips, T H Qiu, N G Copeland, H S Earp, N A Jenkins, and D C Lee (1994)
Genes & Dev. 8, 399-413
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Transgenic mice provide new insights into the role of TGF-alpha during epidermal development and differentiation..
R Vassar and E Fuchs (1991)
Genes & Dev. 5, 714-727
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