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Science 19 July 1985:
Vol. 229. no. 4710, pp. 238 - 242
DOI: 10.1126/science.2409599
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Articles

Science, Vol 229, Issue 4710, 238-242
Copyright © 1985 by American Association for the Advancement of Science

articles

Neurotrophic factors

H Thoenen and D Edgar

In addition to nerve growth factor (NGF), many proteins present in soluble tissue extracts and in the extracellular matrix influence the survival and development of cultured neurons. The structure, synthesis, and mechanism of action of NGF as a neurotrophic factor are considered along with the experiments on the new putative trophic molecules.


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