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Science 24 May 1985:
Vol. 228. no. 4702, pp. 999 - 1002
DOI: 10.1126/science.2408335
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Articles

Science, Vol 228, Issue 4702, 999-1002
Copyright © 1985 by American Association for the Advancement of Science

articles

A catalytic RNA and its gene from Salmonella typhimurium

M Baer and S Altman

The gene for the RNA subunit (M1 RNA) of ribonuclease P from Salmonella typhimurium directs the synthesis of an RNA that can cleave transfer RNA precursor molecules. The mature M1 RNA coded for by Salmonella typhimurium is 375 nucleotides long and has six nucleotide changes in comparison to M1 RNA from Escherichia coli. The regions for promotion and termination of transcription are closely conserved, but adjacent regions of nucleotide sequences show considerable drift.


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