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Science 15 March 1985:
Vol. 227. no. 4692, pp. 1349 - 1351
DOI: 10.1126/science.3883487
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Articles

Science, Vol 227, Issue 4692, 1349-1351
Copyright © 1985 by American Association for the Advancement of Science

articles

Diagnostic ultrasound and sister chromatid exchanges: failure to reproduce positive findings

V Ciaravino, A Brulfert, MW Miller, D Jacobson-Kram, and WF Morgan

Human lymphocytes were exposed in vitro to ultrasound from two clinical devices, one of which was previously reported to have increased the frequency of sister chromatid exchanges. The ultrasonic exposures had no significant effect on the frequency of sister chromatid exchanges from three blood donors. Exposure to ultrasound also had no effect on cell cycle progression. A concomitant positive control (mitomycin C) resulted in a significant increase in sister chromatid exchanges.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)