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Science 1 March 1985:
Vol. 227. no. 4690, pp. 1038 - 1040
DOI: 10.1126/science.2983418
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Articles

Science, Vol 227, Issue 4690, 1038-1040
Copyright © 1985 by American Association for the Advancement of Science

articles

Location of the c-yes gene on the human chromosome and its expression in various tissues

K Semba, Y Yamanashi, M Nishizawa, J Sukegawa, M Yoshida, M Sasaki, T Yamamoto, and K Toyoshima

Analysis of DNA from human embryo fibroblasts showed that ten Eco RI fragments were hybridizable with the Yamaguchi sarcoma virus oncogene (v-yes). Four of the Eco RI fragments were assigned to chromosome 18 and one to chromosome 6. There was evidence for multiple copies of yes-related genes in the human genome; however, only a single RNA species, 4.8 kilobases in length, was related to yes in various cells.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Identification of a chromosome 18q gene that is altered in colorectal cancers.
E. Fearon, K. Cho, J. Nigro, S. Kern, J. Simons, J. Ruppert, Hamilton SR, A. Preisinger, G Thomas, K. Kinzler, et al. (1990)
Science 247, 49-56
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