Science 26 October 1984: Vol. 226. no. 4673, pp. 409 - 416 DOI: 10.1126/science.6494891

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Articles

Lin-28 interaction with the Let-7 precursor loop mediates regulated microRNA processing.

M. A. Newman, J. M. Thomson, and S. M. Hammond (2008)
RNA 14, 1539-1549
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Drosophila let-7 microRNA is required for remodeling of the neuromusculature during metamorphosis.

N. S. Sokol, P. Xu, Y.-N. Jan, and V. Ambros (2008)
Genes & Dev. 22, 1591-1596
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The Caenorhabditis elegans PcG-like Gene sop-2 Regulates the Temporal and Sexual Specificities of Cell Fates.

Q. Cai, Y. Sun, X. Huang, C. Guo, Y. Zhang, Z. Zhu, and H. Zhang (2008)
Genetics 178, 1445-1456
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The let-7 MicroRNA Represses Cell Proliferation Pathways in Human Cells.

C. D. Johnson, A. Esquela-Kerscher, G. Stefani, M. Byrom, K. Kelnar, D. Ovcharenko, M. Wilson, X. Wang, J. Shelton, J. Shingara, et al. (2007)
Cancer Res. 67, 7713-7722
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The Micro-Ribonucleic Acid (miRNA) miR-206 Targets the Human Estrogen Receptor-{alpha} (ER{alpha}) and Represses ER{alpha} Messenger RNA and Protein Expression in Breast Cancer Cell Lines.

B. D. Adams, H. Furneaux, and B. A. White (2007)
Mol. Endocrinol. 21, 1132-1147
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Coordinate Suppression of ERBB2 and ERBB3 by Enforced Expression of Micro-RNA miR-125a or miR-125b.

G. K. Scott, A. Goga, D. Bhaumik, C. E. Berger, C. S. Sullivan, and C. C. Benz (2007)
J. Biol. Chem. 282, 1479-1486
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The mir-84 and let-7 paralogous microRNA genes of Caenorhabditis elegans direct the cessation of molting via the conserved nuclear hormone receptors NHR-23 and NHR-25.

G. D. Hayes, A. R. Frand, and G. Ruvkun (2006)
Development 133, 4631-4641
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The 2006 genetics society of america medal..

G. Seydoux (2006)
Genetics 172, 721-722
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Pathway to RAS..

P. W. Sternberg (2006)
Genetics 172, 727-731
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MicroRNA enrichment among short 'ultraconserved' sequences in insects..

T. Tran, P. Havlak, and J. Miller (2006)
Nucleic Acids Res. 34, e65
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A novel C. elegans zinc finger transcription factor, lsy-2, required for the cell type-specific expression of the lsy-6 microRNA.

R. J. Johnston Jr and O. Hobert (2005)
Development 132, 5451-5460
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Selectionism and Neutralism in Molecular Evolution.

M. Nei (2005)
Mol. Biol. Evol. 22, 2318-2342
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Negative regulation of nuclear divisions in Caenorhabditis elegans by retinoblastoma and RNA interference-related genes.

A. Grishok and P. A. Sharp (2005)
PNAS 102, 17360-17365
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Micro-RNA Regulation of the Mammalian lin-28 Gene during Neuronal Differentiation of Embryonal Carcinoma Cells.

L. Wu and J. G. Belasco (2005)
Mol. Cell. Biol. 25, 9198-9208
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MicroRNA functions in animal development and human disease.

I. Alvarez-Garcia and E. A. Miska (2005)
Development 132, 4653-4662
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Intrinsic and extrinsic regulators of developmental timing: from miRNAs to nutritional cues.

A. E. Rougvie (2005)
Development 132, 3787-3798
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Gene Regulatory Networks Special Feature: Transcriptional network underlying Caenorhabditis elegans vulval development.

T. Inoue, M. Wang, T. O. Ririe, J. S. Fernandes, and P. W. Sternberg (2005)
PNAS 102, 4972-4977
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The C. elegans heterochronic gene lin-46 affects developmental timing at two larval stages and encodes a relative of the scaffolding protein gephyrin.

A. S.-R. Pepper, J. E. McCane, K. Kemper, D. A. Yeung, R. C. Lee, V. Ambros, and E. G. Moss (2004)
Development 131, 2049-2059
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Numerous microRNPs in neuronal cells containing novel microRNAs.

J. DOSTIE, Z. MOURELATOS, M. YANG, A. SHARMA, and G. DREYFUSS (2003)
RNA 9, 180-186
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Identification of spatial and temporal cues that regulate postembryonic expression of axon maintenance factors in the C. elegans ventral nerve cord.

O. Aurelio, T. Boulin, and O. Hobert (2003)
Development 130, 599-610
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Endogenous and Silencing-Associated Small RNAs in Plants.

C. Llave, K. D. Kasschau, M. A. Rector, and J. C. Carrington (2002)
PLANT CELL 14, 1605-1619
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Precocious Expression of the Glide/Gcm Glial-Promoting Factor in Drosophila Induces Neurogenesis.

V. Van De Bor, P. Heitzler, S. Leger, C. Plessy, and A. Giangrande (2002)
Genetics 160, 1095-1106
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Genes Regulating Touch Cell Development in Caenorhabditis elegans.

H. Du and M. Chalfie (2001)
Genetics 158, 197-207
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REF-1, a protein with two bHLH domains, alters the pattern of cell fusion in C. elegans by regulating Hox protein activity.

S Alper and C Kenyon (2001)
Development 128, 1793-1804
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Control of Vulval Cell Division Number in the Nematode Oscheius/Dolichorhabditis sp. CEW1.

M.-L. Dichtel, S. Louvet-Vallée, M. E. Viney, M.-A. Félix, and P. W. Sternberg (2001)
Genetics 157, 183-197
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Isoform-Specific Mutations in the Caenorhabditis elegans Heterochronic Gene lin-14 Affect Stage-Specific Patterning.

B. J. Reinhart and G. Ruvkun (2001)
Genetics 157, 199-209
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daf-12 encodes a nuclear receptor that regulates the dauer diapause and developmental age in C. elegans.

A. Antebi, W.-H. Yeh, D. Tait, E. M. Hedgecock, and D. L. Riddle (2000)
Genes & Dev. 14, 1512-1527
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Structure and Function Analysis of LIN-14, a Temporal Regulator of Postembryonic Developmental Events in Caenorhabditis elegans.

Y. Hong, R. C. Lee, and V. Ambros (2000)
Mol. Cell. Biol. 20, 2285-2295
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The basic helix-loop-helix transcription factors LIN-32 and HLH-2 function together in multiple steps of a C. elegans neuronal sublineage.

D. Portman and S. Emmons (2000)
Development 127, 5415-5426
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Regulation of postembryonic G(1) cell cycle progression in Caenorhabditis elegans by a cyclin D/CDK-like complex.

M Park and M. Krause (1999)
Development 126, 4849-4860
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Cell cycle-dependent sequencing of cell fate decisions in Caenorhabditis elegans vulva precursor cells.

V Ambros (1999)
Development 126, 1947-1956
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Identification of Heterochronic Mutants in Caenorhabditis elegans: Temporal Misexpression of a Collagen::Green Fluorescent Protein Fusion Gene.

J. E. Abrahante, E. A. Miller, and A. E. Rougvie (1998)
Genetics 149, 1335-1351
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CHR3: a Caenorhabditis elegans orphan nuclear hormone receptor required for proper epidermal development and molting.

M Kostrouchova, M Krause, Z Kostrouch, and J. Rall (1998)
Development 125, 1617-1626
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daf-12 regulates developmental age and the dauer alternative in Caenorhabditis elegans.

A Antebi, J. Culotti, and E. Hedgecock (1998)
Development 125, 1191-1205
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The terminal differentiation factor LIN-29 is required for proper vulval morphogenesis and egg laying in Caenorhabditis elegans.

J. Bettinger, S Euling, and A. Rougvie (1997)
Development 124, 4333-4342
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A bulged lin-4/lin-14 RNA duplex is sufficient for Caenorhabditis elegans lin-14 temporal gradient formation..

I Ha, B Wightman, and G Ruvkun (1996)
Genes & Dev. 10, 3041-3050
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Reversal of cell fate determination in Caenorhabditis elegans vulval development.

S Euling and V Ambros (1996)
Development 122, 2507-2515
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Stage-specific accumulation of the terminal differentiation factor LIN-29 during Caenorhabditis elegans development.

J. Bettinger, K Lee, and A. Rougvie (1996)
Development 122, 2517-2527
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The Caenorhabditis elegans heterochronic gene pathway controls stage-specific transcription of collagen genes.

Z Liu, S Kirch, and V Ambros (1995)
Development 121, 2471-2478
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The heterochronic gene lin-29 encodes a zinc finger protein that controls a terminal differentiation event in Caenorhabditis elegans.

A. Rougvie and V Ambros (1995)
Development 121, 2491-2500
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Combinatorial control of touch receptor neuron expression in Caenorhabditis elegans.

S Mitani, H Du, D. Hall, M Driscoll, and M Chalfie (1993)
Development 119, 773-783
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A repressor controls the timing and spatial localisation of stalk cell-specific gene expression in Dictyostelium.

A. Harwood, A Early, and J. Williams (1993)
Development 118, 1041-1048
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Negative regulatory sequences in the lin-14 3'-untranslated region are necessary to generate a temporal switch during Caenorhabditis elegans development..

B Wightman, T R Burglin, J Gatto, P Arasu, and G Ruvkun (1991)
Genes & Dev. 5, 1813-1824
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Temporal regulation of lin-14 by the antagonistic action of two other heterochronic genes, lin-4 and lin-28..

P Arasu, B Wightman, and G Ruvkun (1991)
Genes & Dev. 5, 1825-1833
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Floral homeotic mutations produced by transposon-mutagenesis in Antirrhinum majus..

R Carpenter and E S Coen (1990)
Genes & Dev. 4, 1483-1493
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The mec-3 gene of Caenorhabditis elegans requires its own product for maintained expression and is expressed in three neuronal cell types..

J C Way and M Chalfie (1989)
Genes & Dev. 3, 1823-1833
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Heterochronic genes control the stage-specific initiation and expression of the dauer larva developmental program in Caenorhabditis elegans..

Z C Liu and V Ambros (1989)
Genes & Dev. 3, 2039-2049
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The mab-9 gene controls the fate of B, the major male-specific blast cell in the tail region of Caenorhabditis elegans..

A D Chisholm and J Hodgkin (1989)
Genes & Dev. 3, 1413-1423
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The nematode Caenorhabditis elegans.

C Kenyon (1988)
Science 240, 1448-1453
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New Clues to Developmental Timing: Genes that affect developmental timing have been identified; they may serve as raw material for evolutionary change.

J. L. MARX (1984)
Science 226, 425-426
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