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Science 20 July 1984:
Vol. 225. no. 4659, pp. 340 - 342
DOI: 10.1126/science.6740316
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Articles

Science, Vol 225, Issue 4659, 340-342
Copyright © 1984 by American Association for the Advancement of Science

articles

GM1 ganglioside treatment facilitates behavioral recovery from bilateral brain damage

BA Sabel, MD Slavin, and DG Stein

Adult rats with bilateral lesions of the caudate nucleus were treated with GM1 ganglioside. Although animals injected with a control solution were severely impaired in their ability to learn a complex spatial task, those treated with ganglioside were able to learn spatial reversals.


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