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Science 15 June 1984:
Vol. 224. no. 4654, pp. 1247 - 1249
DOI: 10.1126/science.6729452

Articles

Science, Vol 224, Issue 4654, 1247-1249
Copyright © 1984 by American Association for the Advancement of Science


articles

Dietary restriction retards age-related loss of gamma crystallins in the mouse lens

PJ Leveille, R Weindruch, RL Walford, D Bok, and J Horwitz

The soluble crystallins in lenses from diet-restricted and control mice of diverse ages (2, 11, or 30 months) were studied by high-performance liquid chromatography and sodium dodecyl sulfate-polyacrylamide gel electrophoresis. Results obtained with both methods suggest that dietary restriction decelerates age-related loss of soluble gamma crystallins.


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