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Science 16 September 1983:
Vol. 221. no. 4616, pp. 1185 - 1187
DOI: 10.1126/science.6193581
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Articles

Science, Vol 221, Issue 4616, 1185-1187
Copyright © 1983 by American Association for the Advancement of Science

articles

Shark cartilage contains inhibitors of tumor angiogenesis

A Lee and R Langer

Shark cartilage contains a substance that strongly inhibits the growth of new blood vessels toward solid tumors, thereby restricting tumor growth. The abundance of this factor in shark cartilage, in contrast to cartilage from mammalian sources, may make sharks an ideal source of the inhibitor and may help to explain the rarity of neoplasms in these animals.


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Lipid Angiogenic Factor From Omentum.
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