Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Science 12 August 1983:
Vol. 221. no. 4611, pp. 675 - 677
DOI: 10.1126/science.6867738

Articles

Science, Vol 221, Issue 4611, 675-677
Copyright © 1983 by American Association for the Advancement of Science


articles

Ventral posterior thalamic neurons differentially responsive to noxious stimulation of the awake monkey

KL Casey and TJ Morrow

Of 76 cutaneously activated neurons recorded from the ventral posterior thalamus of awake, behaving monkeys, nine were weakly excited by innocuous skin stimulation and responded maximally only when noxious mechanical cutaneous stimuli were delivered within small, contralateral receptive fields. These results show that neurons capable of encoding the spatial and temporal features of noxious stimuli are located in the ventral posterior thalamus of the awake primate.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
A Painful Cutaneous Laser Stimulus Evokes Responses From Single Neurons in the Human Thalamic Principal Somatic Sensory Nucleus Ventral Caudal (Vc).
K. Kobayashi, J. Winberry, C. C. Liu, R. D. Treede, and F. A. Lenz (2009)
J Neurophysiol 101, 2210-2217
   Abstract »    Full Text »    PDF »
Pain and Temperature Encoding in the Human Thalamic Somatic Sensory Nucleus (Ventral caudal): Inhibition-Related Bursting Evoked by Somatic Stimuli.
J.-I. Lee, S. Ohara, P. M. Dougherty, and F. A. Lenz (2005)
J Neurophysiol 94, 1676-1687
   Abstract »    Full Text »    PDF »
Pain Encoding in the Human Forebrain: Binary and Analog Exteroceptive Channels.
F. A. Lenz, S. Ohara, R. H. Gracely, P. M. Dougherty, and S. H. Patel (2004)
J. Neurosci. 24, 6540-6544
   Abstract »    Full Text »    PDF »
Widespread Thalamic Terminations of Fibers Arising in the Superficial Medullary Dorsal Horn of Monkeys and Their Relation to Calbindin Immunoreactivity.
A. Graziano and E. G. Jones (2004)
J. Neurosci. 24, 248-256
   Abstract »    Full Text »    PDF »
Medial Lateral Extent of Thermal and Pain Sensations Evoked By Microstimulation in Somatic Sensory Nuclei of Human Thalamus.
S. Ohara and F. A. Lenz (2003)
J Neurophysiol 90, 2367-2377
   Abstract »    Full Text »    PDF »
Central Neural Mechanisms that Interrelate Sensory and Affective Dimensions of Pain.
D. D. Price (2002)
Mol. Interv. 2, 392-403
   Abstract »    Full Text »    PDF »
Somatotopic Activation in the Human Trigeminal Pain Pathway.
A. F. M. DaSilva, L. Becerra, N. Makris, A. M. Strassman, R. G. Gonzalez, N. Geatrakis, and D. Borsook (2002)
J. Neurosci. 22, 8183-8192
   Abstract »    Full Text »    PDF »
Segregation of Nociceptive and Non-Nociceptive Networks in the Squirrel Monkey Somatosensory Thalamus.
A. V. Apkarian, T. Shi, J. Bruggemann, and L. R. Airapetian (2000)
J Neurophysiol 84, 484-494
   Abstract »    Full Text »    PDF »
Painful Stimuli Evoke Potentials Recorded From the Parasylvian Cortex in Humans.
F. A. Lenz, M. Rios, D. Chau, G. L. Krauss, T. A. Zirh, and R. P. Lesser (1998)
J Neurophysiol 80, 2077-2088
   Abstract »    Full Text »    PDF »
Functional MRI Study of Thalamic and Cortical Activations Evoked by Cutaneous Heat, Cold, and Tactile Stimuli.
K. D. Davis, C. L. Kwan, A. P. Crawley, and D. J. Mikulis (1998)
J Neurophysiol 80, 1533-1546
   Abstract »    Full Text »    PDF »
Cerebral Processing of Acute Skin and Muscle Pain in Humans.
P. Svensson, S. Minoshima, A. Beydoun, T. J. Morrow, and K. L. Casey (1997)
J Neurophysiol 78, 450-460
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)