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Science 12 August 1983:
Vol. 221. no. 4611, pp. 659 - 661
DOI: 10.1126/science.6867734
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Articles

Science, Vol 221, Issue 4611, 659-661
Copyright © 1983 by American Association for the Advancement of Science

articles

5-hydroxytryptophan elevates serum melatonin

MA Namboodiri, D Sugden, DC Klein, and IN Mefford

Daytime administration of 5-hydroxytryptophan to sheep elevated serum melatonin more than sevenfold within 2 hours. This suggests that administration of 5-hydroxytryptophan could be used as the basis of a clinical test of pineal function and that melatonin might mediate some clinical effects of 5-hydroxytryptophan.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Neuroendocrine Response to 5-Hydroxytryptophan in Seasonal Affective Disorder.
F. M. Jacobsen, D. A. Sack, T. A. Wehr, S. Rogers, and N. E. Rosenthal (1987)
Arch Gen Psychiatry 44, 1086-1091
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