Related Content
Search Google Scholar for:
|
|
Science 5 August 1983: Vol. 221. no. 4610, pp. 551 - 553 DOI: 10.1126/science.6306768
|
|
Articles
Science, Vol 221, Issue 4610, 551-553
Copyright © 1983 by American Association for the Advancement of Science
High efficiency DNA-mediated transformation of primate cells
C Gorman,
R Padmanabhan,
and
BH Howard
Tissue culture cells from several mammalian species, including three primate lines, were transfected with recombinant vectors carrying Escherichia coli xanthine-guanine phosphoribosyltransferase or Tn5 aminoglycoside phosphotransferase dominant selectable markers. Human HeLa and SV40-transformed xeroderma pigmentosum cells exhibited stable transformation frequencies of at least 10(-3) (0.1 percent). CV-1, an African green monkey kidney cell line, could be stably transformed with the exceptionally high frequency of 6 X 10(-2) (6 percent).
THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
- Nuclear Factor-{kappa}B Binds to the Epstein-Barr Virus LMP1 Promoter and Upregulates Its Expression.
- P. Johansson, A. Jansson, U. Ruetschi, and L. Rymo (2009)
J. Virol.
83, 1393-1401
| Abstract »
| Full Text »
| PDF »
- Negative regulation of the SH2-homology containing protein-tyrosine phosphatase-1 (SHP-1) P2 promoter by the HTLV-1 Tax oncoprotein.
- J. Cheng, A. R. Kydd, K. Nakase, K. M. Noonan, A. Murakami, H. Tao, M. Dwyer, C. Xu, Q. Zhu, and W. A. Marasco (2007)
Blood
110, 2110-2120
| Abstract »
| Full Text »
| PDF »
- Role of deadenylation and AUF1 binding in the pH-responsive stabilization of glutaminase mRNA.
- J. M. Schroeder, H. Ibrahim, L. Taylor, and N. P. Curthoys (2006)
Am J Physiol Renal Physiol
290, F733-F740
| Abstract »
| Full Text »
| PDF »
- A mechanism of AP-1 suppression through interaction of c-Fos with lamin A/C.
- C. Ivorra, M. Kubicek, J. M. Gonzalez, S. M. Sanz-Gonzalez, A. Alvarez-Barrientos, J.-E. O'Connor, B. Burke, and V. Andres (2006)
Genes & Dev.
20, 307-320
| Abstract »
| Full Text »
| PDF »
- cAMP-dependent stabilization of phosphoenolpyruvate carboxykinase mRNA in LLC-PK1-F+ kidney cells.
- P. S. Dhakras, S. Hajarnis, L. Taylor, and N. P. Curthoys (2006)
Am J Physiol Renal Physiol
290, F313-F318
| Abstract »
| Full Text »
| PDF »
- The SET domain protein Metnase mediates foreign DNA integration and links integration to nonhomologous end-joining repair.
- S.-H. Lee, M. Oshige, S. T. Durant, K. K. Rasila, E. A. Williamson, H. Ramsey, L. Kwan, J. A. Nickoloff, and R. Hromas (2005)
PNAS
102, 18075-18080
| Abstract »
| Full Text »
| PDF »
- 3'-Untranslated Region of Phosphoenolpyruvate Carboxykinase mRNA Contains Multiple Instability Elements That Bind AUF1.
- S. Hajarnis, J. M. Schroeder, and N. P. Curthoys (2005)
J. Biol. Chem.
280, 28272-28280
| Abstract »
| Full Text »
| PDF »
- Lipopolysaccharide induces 5-lipoxygenase-activating protein gene expression in THP-1 cells via a NF-{kappa}B and C/EBP-mediated mechanism.
- K. J. Serio, K. V. Reddy, and T. D. Bigby (2005)
Am J Physiol Cell Physiol
288, C1125-C1133
| Abstract »
| Full Text »
| PDF »
- Activation of the Tumor-Specific Death Effector Apoptin and Its Kinase by an N-Terminal Determinant of Simian Virus 40 Large T Antigen.
- Y.-H. Zhang, K. Kooistra, A. Pietersen, J. L. Rohn, and M. H. M. Noteborn (2004)
J. Virol.
78, 9965-9976
| Abstract »
| Full Text »
| PDF »
- PU.1 Binding to ets Motifs within the Equine Infectious Anemia Virus Long Terminal Repeat (LTR) Enhancer: Regulation of LTR Activity and Virus Replication in Macrophages.
- R. Hines, B. R. Sorensen, M. A. Shea, and W. Maury (2004)
J. Virol.
78, 3407-3418
| Abstract »
| Full Text »
| PDF »
- Simian Virus 40-Based Replication of Catalytically Inactive Human Immunodeficiency Virus Type 1 Integrase Mutants in Nonpermissive T Cells and Monocyte-Derived Macrophages.
- R. Lu, N. Nakajima, W. Hofmann, M. Benkirane, K. Teh-Jeang, J. Sodroski, and A. Engelman (2004)
J. Virol.
78, 658-668
| Abstract »
| Full Text »
| PDF »
- pH-responsive stabilization of glutamate dehydrogenase mRNA in LLC-PK1-F+ cells.
- J. M. Schroeder, W. Liu, and N. P. Curthoys (2003)
Am J Physiol Renal Physiol
285, F258-F265
| Abstract »
| Full Text »
| PDF »
- Lipopolysaccharide Down-Regulates the Leukotriene C4 Synthase Gene in the Monocyte-Like Cell Line, THP-1.
- K. J. Serio, S. C. Johns, L. Luo, C. R. Hodulik, and T. D. Bigby (2003)
J. Immunol.
170, 2121-2128
| Abstract »
| Full Text »
| PDF »
- Non-contact positions impose site selectivity on Cre recombinase.
- A. W. Rufer and B. Sauer (2002)
Nucleic Acids Res.
30, 2764-2771
| Abstract »
| Full Text »
| PDF »
- Pigment Epithelium-Derived Factor Suppresses Ischemia-Induced Retinal Neovascularization and VEGF-Induced Migration and Growth.
- E. J. Duh, H. S. Yang, I. Suzuma, M. Miyagi, E. Youngman, K. Mori, M. Katai, L. Yan, K. Suzuma, K. West, et al. (2002)
Invest. Ophthalmol. Vis. Sci.
43, 821-829
| Abstract »
| Full Text »
| PDF »
- Transient Disruption of Intercellular Junctions Enables Baculovirus Entry into Nondividing Hepatocytes.
- J. P. Bilello, W. E. Delaney IV, F. M. Boyce, and H. C. Isom (2001)
J. Virol.
75, 9857-9871
| Abstract »
| Full Text »
| PDF »
- Inhibitor of the Tissue-Specific Transcription Factor HNF4, a Potential Regulator in Early Xenopus Development.
- G. Peiler, B. Böckmann, H. Nakhei, and G. U. Ryffel (2000)
Mol. Cell. Biol.
20, 8676-8683
| Abstract »
| Full Text »
- A duodenum-specific enhancer regulates expression along three axes in the small intestine.
- M. R. Dusing, A. G. Brickner, S. Y. Lowe, M. B. Cohen, and D. A. Wiginton (2000)
Am J Physiol Gastrointest Liver Physiol
279, G1080-G1093
| Abstract »
| Full Text »
| PDF »
- Mapping and functional analysis of an instability element in phosphoenolpyruvate carboxykinase mRNA.
- O. F. Laterza, L. Taylor, S. Unnithan, L. Nguyen, and N. P. Curthoys (2000)
Am J Physiol Renal Physiol
279, F866-F873
| Abstract »
| Full Text »
| PDF »
- Roles of Autocrine TGF-{beta} Receptor and Smad Signaling in Adipocyte Differentiation.
- L. Choy, J. Skillington, and R. Derynck (2000)
J. Cell Biol.
149, 667-682
| Abstract »
| Full Text »
| PDF »
- In Vitro and In Vivo Characterization of a Mouse Adenovirus Type 1 Early Region 3 Null Mutant.
- A. N. Cauthen, C. C. Brown, and K. R. Spindler (1999)
J. Virol.
73, 8640-8646
| Abstract »
| Full Text »
| PDF »
- Protective effects of transient HO-1 overexpression on susceptibility to oxygen toxicity in lung cells.
- D. M. Suttner, K. Sridhar, C. S. Lee, T. Tomura, T. N. Hansen, and P. A. Dennery (1999)
Am J Physiol Lung Cell Mol Physiol
276, L443-L451
| Abstract »
| Full Text »
| PDF »
- Characterization of a Nuclear Deformed Epidermal Autoregulatory Factor-1 (DEAF-1)-Related (NUDR) Transcriptional Regulator Protein.
- J. I. Huggenvik, R. J. Michelson, M. W. Collard, A. J. Ziemba, P. Gurley, and K. A. Mowen (1998)
Mol. Endocrinol.
12, 1619-1639
| Abstract »
| Full Text »
- Thyroid Hormone Receptor Does Not Heterodimerize with the Vitamin D Receptor but Represses Vitamin D Receptor-Mediated Transactivation.
- M. Raval-Pandya, L. P. Freedman, H. Li, and S. Christakos (1998)
Mol. Endocrinol.
12, 1367-1379
| Abstract »
| Full Text »
- Apolipoprotein(a) Enhances Platelet Responses to the Thrombin Receptor–Activating Peptide SFLLRN.
- M. L. Rand, W. Sangrar, M. A. Hancock, D. M. Taylor, S. M. Marcovina, M. A. Packham, and M. L. Koschinsky (1998)
Arterioscler Thromb Vasc Biol
18, 1393-1399
| Abstract »
| Full Text »
| PDF »
- The Role of Enhancer A in the Locus-Specific Transactivation of Classical and Nonclassical HLA Class I Genes by Nuclear Factor {kappa}B.
- S. J. P. Gobin, V. Keijsers, M. van Zutphen, and P. J. van den Elsen (1998)
J. Immunol.
161, 2276-2283
| Abstract »
| Full Text »
| PDF »
- B-Cell Lymphoma Induction by Akv Murine Leukemia Viruses Harboring One or Both Copies of the Tandem Repeat in the U3 Enhancer.
- J. Lovmand, A. B. Sorensen, J. Schmidt, M. Ostergaard, A. Luz, and F. S. Pedersen (1998)
J. Virol.
72, 5745-5756
| Abstract »
| Full Text »
| PDF »
- Wild-type p53-mediated Induction of Rat mdr1b Expression by the Anticancer Drug Daunorubicin.
- G. Zhou and M. T. Kuo (1998)
J. Biol. Chem.
273, 15387-15394
| Abstract »
| Full Text »
| PDF »
- Retrotransposition of Nonviral RNAs in an Avian Packaging Cell Line.
- R. Lum and M. L. Linial (1998)
J. Virol.
72, 4057-4064
| Abstract »
| Full Text »
| PDF »
- Lens-Specific Gene Recruitment of zeta -Crystallin through Pax6, Nrl-Maf, and Brain Suppressor Sites.
- R. Sharon-Friling, J. Richardson, S. Sperbeck, D. Lee, M. Rauchman, R. Maas, A. Swaroop, and G. Wistow (1998)
Mol. Cell. Biol.
18, 2067-2076
| Abstract »
| Full Text »
- The Product of the Herpes Simplex Virus Type 1 UL25 Gene Is Required for Encapsidation but Not for Cleavage of Replicated Viral DNA.
- A. R. McNab, P. Desai, S. Person, L. L. Roof, D. R. Thomsen, W. W. Newcomb, J. C. Brown, and F. L. Homa (1998)
J. Virol.
72, 1060-1070
| Abstract »
| Full Text »
| PDF »
- The C-terminal Subdomain Makes an Important Contribution to the DNA Binding Activity of the Pax-3 Paired Domain.
- K. J. Vogan and P. Gros (1997)
J. Biol. Chem.
272, 28289-28295
| Abstract »
| Full Text »
| PDF »
- Upregulation of Low Density Lipoprotein Receptor by Gemfibrozil, a Hypolipidemic Agent, in Human Hepatoma Cells Through Stabilization of mRNA Transcripts.
- D. Goto, T. Okimoto, M. Ono, H. Shimotsu, K. Abe, Y. Tsujita, and M. Kuwano (1997)
Arterioscler Thromb Vasc Biol
17, 2707-2712
| Abstract »
| Full Text »
- Regulation of Duodenal Specific Expression of the Human Adenosine Deaminase Gene.
- M. R. Dusing, A. G. Brickner, M. B. Thomas, and D. A. Wiginton (1997)
J. Biol. Chem.
272, 26634-26642
| Abstract »
| Full Text »
| PDF »
- The Dynamics of the Transcriptional Response to Cyclic Adenosine 3',5'-Monophosphate: Recurrent Inducibility and Refractory Phase.
- M. Lamas and P. Sassone-Corsi (1997)
Mol. Endocrinol.
11, 1415-1424
| Abstract »
| Full Text »
- Ectopic ICER Expression in Pituitary Corticotroph AtT20 Cells: Effects on Morphology, Cell Cycle, and Hormonal Production.
- M. Lamas, C. Molina, N. S. Foulkes, E. Jansen, and P. Sassone-Corsi (1997)
Mol. Endocrinol.
11, 1425-1434
| Abstract »
| Full Text »
- NF-kappa B-mediated Induction of mdr1b Expression by Insulin in Rat Hepatoma Cells.
- G. Zhou and M. T. Kuo (1997)
J. Biol. Chem.
272, 15174-15183
| Abstract »
| Full Text »
| PDF »
- The Type II Transforming Growth Factor-beta Receptor Autophosphorylates Not Only on Serine and Threonine but Also on Tyrosine Residues.
- S. Lawler, X.-H. Feng, R.-H. Chen, E. M. Maruoka, C. W. Turck, I. Griswold-Prenner, and R. Derynck (1997)
J. Biol. Chem.
272, 14850-14859
| Abstract »
| Full Text »
| PDF »
- The Paired-domain Regulates DNA Binding by the Homeodomain within the Intact Pax-3 Protein.
- D. A. Underhill and P. Gros (1997)
J. Biol. Chem.
272, 14175-14182
| Abstract »
| Full Text »
| PDF »
- Cell-free tumor antigen peptide-based cancer vaccines.
- W. Schmidt, M. Buschle, W. Zauner, H. Kirlappos, K. Mechtler, B. Trska, and M. L. Birnstiel (1997)
PNAS
94, 3262-3267
| Abstract »
| Full Text »
| PDF »
- Post-Transcriptional Regulation of the GAP-43 Gene by Specific Sequences in the 3' Untranslated Region of the mRNA.
- K.-C. Tsai, V. V. Cansino, D. T. Kohn, R. L. Neve, and N. I. Perrone-Bizzozero (1997)
J. Neurosci.
17, 1950-1958
| Abstract »
| Full Text »
| PDF »
- The Binding Activity of the Macrophage Lipoprotein(a)/Apolipoprotein(a) Receptor Is Induced by Cholesterol via a Post-translational Mechanism and Recognizes Distinct Kringle Domains on Apolipoprotein(a).
- G. A. Keesler, B. R. Gabel, C. M. Devlin, M. L. Koschinsky, and I. Tabas (1996)
J. Biol. Chem.
271, 32096-32104
| Abstract »
| Full Text »
| PDF »
- Lipoprotein(a) Assembly: Quantitative Assessment of the Role of Apo(a) Kringle IV Types 2-10 in Particle Formation.
- B. R. Gabel, L. F. May, S. M. Marcovina, and M. L. Koschinsky (1996)
Arterioscler Thromb Vasc Biol
16, 1559-1567
| Abstract »
| Full Text »
- Role of p300-family proteins in E1A oncogene induction of cytolytic susceptibility and tumor cell rejection.
- J. L. Cook, C. K. Krantz, and B. A. Routes (1996)
PNAS
93, 13985-13990
| Abstract »
| Full Text »
| PDF »
- Membrane Localization of cAMP-dependent Protein Kinase Amplifies cAMP Signaling to the Nucleus in PC12 Cells.
- S. Cassano, A. Gallo, V. Buccigrossi, A. Porcellini, R. Cerillo, M. E. Gottesman, and E. V. Avvedimento (1996)
J. Biol. Chem.
271, 29870-29875
| Abstract »
| Full Text »
| PDF »
- Analysis of the Role of Calmodulin Binding and Sequestration in Neuromodulin (GAP-43) Function.
- C. Gamby, M. C. Waage, R. G. Allen, and L. Baizer (1996)
J. Biol. Chem.
271, 26698-26705
| Abstract »
| Full Text »
| PDF »
- The Chick alpha 2(I) Collagen Gene Contains Two Functional Promoters, and Its Expression in Chondrocytes Is Regulated at Both Transcriptional and Post-transcriptional Levels.
- K. M. Pallante, Z. Niu, Y. Zhao, A. J. Cohen, H.-D. Nah, and S. L. Adams (1996)
J. Biol. Chem.
271, 25233-25239
| Abstract »
| Full Text »
| PDF »
- Identification and Characterization of Basal and Cyclic AMP Response Elements in the Promoter of the Rat Hexokinase II Gene.
- H. Osawa, R. B. Robey, R. L. Printz, and D. K. Granner (1996)
J. Biol. Chem.
271, 17296-17303
| Abstract »
| Full Text »
| PDF »
- De Novo Expression of Transfected Human Class 1 Aldehyde Dehydrogenase (ALDH) Causes Resistance to Oxazaphosphorine Anti-cancer Alkylating Agents in Hamster V79 Cell Lines.
- K. D. Bunting and A. J. Townsend (1996)
J. Biol. Chem.
271, 11884-11890
| Abstract »
| Full Text »
| PDF »
- Growth-associated Protein-43 (GAP-43) Facilitates Peptide Hormone Secretion in Mouse Anterior Pituitary AtT-20 Cells.
- C. Gamby, M. C. Waage, R. G. Allen, and L. Baizer (1996)
J. Biol. Chem.
271, 10023-10028
| Abstract »
| Full Text »
| PDF »
- Regulation of Activating Transcription Factor-1 and the cAMP Response Element-binding Protein by Ca[IMAGE]/Calmodulin-dependent Protein Kinases Type I, II, and IV.
- P. Sun, L. Lou, and R. A. Maurer (1996)
J. Biol. Chem.
271, 3066-3073
| Abstract »
| Full Text »
| PDF »
- Phosphorylation-dependent Interaction of the Cytoplasmic Domains of the Type I and Type II Transforming Growth Factor-[IMAGE] Receptors.
- R.-H. Chen, H. L. Moses, E. M. Maruoka, R. Derynck, and M. Kawabata (1995)
J. Biol. Chem.
270, 12235-12241
| Abstract »
| Full Text »
| PDF »
- Characterization of the Human Tryptophan Hydroxylase Gene Promoter.
- S. Boularand, M.èl. C. Darmon, P. Ravassard, and J. Mallet (1995)
J. Biol. Chem.
270, 3757-3764
| Abstract »
| Full Text »
| PDF »
- Differential activation of CREB by Ca2+/calmodulin-dependent protein kinases type II and type IV involves phosphorylation of a site that negatively regulates activity..
- P Sun, H Enslen, P S Myung, and R A Maurer (1994)
Genes & Dev.
8, 2527-2539
| Abstract »
| PDF »
- Identification of a locus control region in the immunoglobulin heavy-chain locus that deregulates c-myc expression in plasmacytoma and Burkitt's lymphoma cells..
- L Madisen and M Groudine (1994)
Genes & Dev.
8, 2212-2226
| Abstract »
| PDF »
- The murine type II TGF-beta receptor has a coincident embryonic expression and binding preference for TGF-beta 1.
- S Lawler, A. Candia, R Ebner, L Shum, A. Lopez, H. Moses, C. Wright, and R Derynck (1994)
Development
120, 165-175
| Abstract »
| PDF »
- Determination of type I receptor specificity by the type II receptors for TGF-beta or activin.
- R Ebner, R. Chen, S Lawler, T Zioncheck, and R Derynck (1993)
Science
262, 900-902
| Abstract »
| PDF »
- Inactivation of the type II receptor reveals two receptor pathways for the diverse TGF-beta activities.
- R. Chen, R Ebner, and R Derynck (1993)
Science
260, 1335-1338
| Abstract »
| PDF »
- Cloning of a type I TGF-beta receptor and its effect on TGF-beta binding to the type II receptor.
- R Ebner, R. Chen, L Shum, S Lawler, T. Zioncheck, A Lee, A. Lopez, and R Derynck (1993)
Science
260, 1344-1348
| Abstract »
| PDF »
- A 300 bp 5'-upstream sequence of a differentiation-dependent rabbit K3 keratin gene can serve as a keratinocyte-specific promoter.
- R. Wu, S Galvin, S. Wu, C Xu, M Blumenberg, and T. Sun (1993)
J. Cell Sci.
105, 303-316
| Abstract »
| PDF »
- The block to transcriptional elongation within the human c-myc gene is determined in the promoter-proximal region..
- A Krumm, T Meulia, M Brunvand, and M Groudine (1992)
Genes & Dev.
6, 2201-2213
| Abstract »
| PDF »
- Regulation of a human epidermal keratin gene: sequences and nuclear factors involved in keratinocyte-specific transcription..
- A Leask, M Rosenberg, R Vassar, and E Fuchs (1990)
Genes & Dev.
4, 1985-1998
| Abstract »
| PDF »
- Requirement for activin A and transforming growth factor--beta 1 pro-regions in homodimer assembly.
- A. Gray and A. Mason (1990)
Science
247, 1328-1330
| Abstract »
| PDF »
- Gene targeting at the human CD4 locus by epitope addition..
- M Jasin, S J Elledge, R W Davis, and P Berg (1990)
Genes & Dev.
4, 157-166
| Abstract »
| PDF »
- The block to transcription elongation is promoter dependent in normal and Burkitt's lymphoma c-myc alleles..
- C A Spencer, R C LeStrange, U Novak, W S Hayward, and M Groudine (1990)
Genes & Dev.
4, 75-88
| Abstract »
| PDF »
- The growth hormone-binding protein in rat serum is an alternatively spliced form of the rat growth hormone receptor..
- W R Baumbach, D L Horner, and J S Logan (1989)
Genes & Dev.
3, 1199-1205
| Abstract »
| PDF »
- Histone H5 in the control of DNA synthesis and cell proliferation.
- J. Sun, R Wiaderkiewicz, and A Ruiz-Carrillo (1989)
Science
245, 68-71
| Abstract »
| PDF »
- Differential requirements for cell-specific elastase I enhancer domains in transfected cells and transgenic mice..
- G H Swift, F Kruse, R J MacDonald, and R E Hammer (1989)
Genes & Dev.
3, 687-696
| Abstract »
| PDF »
- Constitutive expression of c-fos antisense RNA blocks c-fos gene induction by interferon and by phorbol ester and reduces c-myc expression in F9 embryonal carcinoma cells..
- B Z Levi and K Ozato (1988)
Genes & Dev.
2, 554-566
| Abstract »
| PDF »
- A parathyroid hormone-related protein implicated in malignant hypercalcemia: cloning and expression.
- L. Suva, G. Winslow, R. Wettenhall, R. Hammonds, J. Moseley, H Diefenbach-Jagger, C. Rodda, B. Kemp, H Rodriguez, E. Chen, et al. (1987)
Science
237, 893-896
| Abstract »
| PDF »
- Expression and properties of two types of protein kinase C: alternative splicing from a single gene.
- Y Ono, U Kikkawa, K Ogita, T Fujii, T Kurokawa, Y Asaoka, K Sekiguchi, K Ase, K Igarashi, and Y Nishizuka (1987)
Science
236, 1116-1120
| Abstract »
| PDF »
- Primary rat embryo cells transformed by one or two oncogenes show different metastatic potentials.
- R Pozzatti, R Muschel, J Williams, R Padmanabhan, B Howard, L Liotta, and G Khoury (1986)
Science
232, 223-227
| Abstract »
| PDF »
- Cell-specific expression of the rat insulin gene: evidence for role of two distinct 5' flanking elements.
- T Edlund, M. Walker, P. Barr, and W. Rutter (1985)
Science
230, 912-916
| Abstract »
| PDF »
- Heat Shock Protein 70 Inhibits Apoptosis Downstream of Cytochrome c Release and Upstream of Caspase-3 Activation.
- C.-Y. Li, J.-S. Lee, Y.-G. Ko, J.-I. Kim, and J.-S. Seo (2000)
J. Biol. Chem.
275, 25665-25671
| Abstract »
| Full Text »
| PDF »
- Identification and Characterization of Cell Lines with a Defect in a Post-adsorption Stage of Sendai Virus-mediated Membrane Fusion.
- A. Eguchi, T. Kondoh, H. Kosaka, T. Suzuki, H. Momota, A. Masago, T. Yoshida, H. Taira, A. Ishii-Watabe, J. Okabe, et al. (2000)
J. Biol. Chem.
275, 17549-17555
| Abstract »
| Full Text »
| PDF »
|
|