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Science 10 June 1983:
Vol. 220. no. 4602, pp. 1185 - 1187
DOI: 10.1126/science.6857244
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Articles

Science, Vol 220, Issue 4602, 1185-1187
Copyright © 1983 by American Association for the Advancement of Science

articles

Endogenous opiates mediate radiogenic behavioral change

GA Mickley, KE Stevens, GA White, and GL Gibbs

Exposure of C57BL/6J mice to ionizing radiation caused stereotypical locomotor hyperactivity similar to that produced by morphine. Naloxone administration prevented this radiation-induced behavioral activation. These results support the hypothesis that endorphins are involved in some aspects of radiogenic behavioral change.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)