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Science 10 June 1983:
Vol. 220. no. 4602, pp. 1170 - 1173
DOI: 10.1126/science.6857240
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Articles

Science, Vol 220, Issue 4602, 1170-1173
Copyright © 1983 by American Association for the Advancement of Science

articles

In vivo one-dimensional imaging of phosphorus metabolites by phosphorus-31 nuclear magnetic resonance

JC Haselgrove, VH Subramanian, JS Leigh Jr, L Gyulai, and B Chance

A phosphorus-31 nuclear magnetic resonance imaging technique has been used to obtain information on phosphorus metabolites from different spatial regions of tissues in vivo. The technique for selection of planes through the tissue is based on phase-encoding of spin echoes and was used to obtain one-dimensional discrimination of phosphorus-31 spectra from different parts of the tissue simultaneously. Specimens were resolved into 16 distinct slices and a signal-to-noise ratio of about 20 to 1 was obtained in 1/2 hour. Results are presented for phantoms, rat legs, and gerbil heads.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Nuclear magnetic resonance technology for medical studies.
T. Budinger and P. Lauterbur (1984)
Science 226, 288-298
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Nuclear Magnetic Resonance: Potential Applications in Clinical Cardiology.
G. M. Pohost and A. V. Ratner (1984)
JAMA 251, 1304-1309
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