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Science 6 May 1983:
Vol. 220. no. 4597, pp. 609 - 610
DOI: 10.1126/science.6573024
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Articles

Science, Vol 220, Issue 4597, 609-610
Copyright © 1983 by American Association for the Advancement of Science

articles

Inhibition of gastric acid secretion in the gastric brooding frog, Rheobatrachus silus

MJ Tyler, DJ Shearman, R Franco, P O'Brien, RF Seamark, and R Kelly

The female gastric brooding frog Rheobatrachus silus broods its young in its stomach. A substance that inhibits gastric acid secretion in a toad stomach preparation in vitro appears to be secreted by the developing young. This substance has been identified as prostaglandin E2. Rheobatrachus silus may thus have developed a mechanism whereby prostaglandin secreted by the larvae inhibits acid secretion in the stomach of the female until the larvae have completed development and emerged as juvenile frogs by way of the female's mouth.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Immunohistochemical Localization of Microsomal PGE Synthase-1 and Cyclooxygenases in Male Mouse Reproductive Organs.
M. Lazarus, C. J. Munday, N. Eguchi, S. Matsumoto, G. J. Killian, B. K. Kubata, and Y. Urade (2002)
Endocrinology 143, 2410-2419
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