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Science 18 March 1983:
Vol. 219. no. 4590, pp. 1333 - 1335
DOI: 10.1126/science.6828860
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Articles

Science, Vol 219, Issue 4590, 1333-1335
Copyright © 1983 by American Association for the Advancement of Science

articles

Fourier transform infrared difference spectra of intermediates in rhodopsin bleaching

KJ Rothschild, WA Cantore, and H Marrero

The membrane protein rhodopsin is the primary light receptor in vision. Fourier transform infrared difference spectroscopy is sensitive to conformational changes in both the protein and the retinylidene chromophore of rhodopsin. By blocking rhodopsin bleaching at specific intermediates, it is possible to elucidate some of the primary molecular events of vision.


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