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Science 11 March 1983:
Vol. 219. no. 4589, pp. 1221 - 1223
DOI: 10.1126/science.6828851
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Articles

Science, Vol 219, Issue 4589, 1221-1223
Copyright © 1983 by American Association for the Advancement of Science

articles

Exposure to ethylene oxide at work increases sister chromatid exchanges in human peripheral lymphocytes

JW Yager, CJ Hines, and RC Spear

Sister chromatid exchange rates increased significantly in the peripheral lymphocytes of a small group of hospital workers exposed to ethylene oxide for as little as 3.6 minutes per day regularly over a period of months. Results based on breathing zone exposure and task frequency estimates over a 6-month period for 14 workers suggest that sister chromatid exchanges are a sensitive indicator of exposure and that cumulative dose and dose rate are important predictors of sister chromatid exchange response.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Evidence of Neurologic Dysfunction Related to Long-term Ethylene Oxide Exposure.
W. J. Estrin, S. A. Cavalieri, P. Wald, C. E. Becker, J. R. Jones, and J. E. Cone (1987)
Arch Neurol 44, 1283-1286
   Abstract »    PDF »
Epidemiologic Support for Ethylene Oxide as a Cancer-Causing Agent.
C. Hogstedt, L. Aringer, and A. Gustavsson (1986)
JAMA 255, 1575-1578
   Abstract »    PDF »


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