Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 25 February 1983:
Vol. 219. no. 4587, pp. 987 - 988
DOI: 10.1126/science.6297010
Prev | Table of Contents | Next

Articles

Science, Vol 219, Issue 4587, 987-988
Copyright © 1983 by American Association for the Advancement of Science

articles

Ammonium chloride prevents lytic growth of reovirus and helps to establish persistent infection in mouse L cells

WM Canning and BN Fields

Ammonium chloride, a lysosomotropic agent that raises intralysosomal pH, reduces the yield of reovirus during infection of mouse L cells. Subsequent removal of ammonium chloride results in the rapid establishment of a persistent infection.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Inhibition of Endosome-Lysosome System Acidification Enhances Porcine Circovirus 2 Infection of Porcine Epithelial Cells.
G. Misinzo, P. L. Delputte, and H. J. Nauwynck (2008)
J. Virol. 82, 1128-1135
   Abstract »    Full Text »    PDF »
Regulation of polymeric immunoglobulin receptor expression by reovirus.
K. Pal, C. S. Kaetzel, K. Brundage, C. A. Cunningham, and C. F. Cuff (2005)
J. Gen. Virol. 86, 2347-2357
   Abstract »    Full Text »    PDF »
Cathepsin S Supports Acid-independent Infection by Some Reoviruses.
J. W. Golden, J. A. Bahe, W. T. Lucas, M. L. Nibert, and L. A. Schiff (2004)
J. Biol. Chem. 279, 8547-8557
   Abstract »    Full Text »    PDF »
Addition of Exogenous Protease Facilitates Reovirus Infection in Many Restrictive Cells.
J. W. Golden, J. Linke, S. Schmechel, K. Thoemke, and L. A. Schiff (2002)
J. Virol. 76, 7430-7443
   Abstract »    Full Text »    PDF »
Sites and Determinants of Early Cleavages in the Proteolytic Processing Pathway of Reovirus Surface Protein {sigma}3.
J. Jane-Valbuena, L. A. Breun, L. A. Schiff, and M. L. Nibert (2002)
J. Virol. 76, 5184-5197
   Abstract »    Full Text »    PDF »
Virion Disassembly Is Required for Apoptosis Induced by Reovirus.
J. L. Connolly and T. S. Dermody (2002)
J. Virol. 76, 1632-1641
   Abstract »    Full Text »    PDF »
Reovirus Virion-Like Particles Obtained by Recoating Infectious Subvirion Particles with Baculovirus-Expressed sigma 3 Protein: an Approach for Analyzing sigma 3 Functions during Virus Entry.
J. Jané-Valbuena, M. L. Nibert, S. M. Spencer, S. B. Walker, T. S. Baker, Y. Chen, V. E. Centonze, and L. A. Schiff (1999)
J. Virol. 73, 2963-2973
   Abstract »    Full Text »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)