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Science 18 February 1983:
Vol. 219. no. 4586, pp. 856 - 859
DOI: 10.1126/science.6600519

Articles

Science, Vol 219, Issue 4586, 856-859
Copyright © 1983 by American Association for the Advancement of Science


articles

Isolation and transmission of human retrovirus (human t-cell leukemia virus)

M Popovic, PS Sarin, M Robert-Gurroff, VS Kalyanaraman, D Mann, J Minowada, and RC Gallo

Nine new isolates of human T-cell leukemia-lymphoma virus (HTLV) were obtained from cells of seven patients with malignancies of mature T cells and from two clinically normal relatives of a T-cell leukemia patient. These people were from the United States, Israel, the West Indies, and Japan. The virus was detected in the fresh T cells and was isolated from the established T-cell lines. Each isolate is closely related to the first HTLV isolate, and all the new HTLV isolates were transmitted into normal human T cells obtained from the umbilical cord blood of newborns.


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Viruses in human cancers.
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Mikulas Popovic's Letter on The HIV-1/HTLV-IIIB/83 Isolate and the Pooling Experiment.
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   PDF »
Chronic Lymphocytic Leukemia: New Insights into Biology and Therapy.
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   Abstract »    PDF »
Human T cell leukemia viruses use a receptor determined by human chromosome 17.
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   Abstract »    PDF »
The tat gene of human T-lymphotropic virus type 1 induces mesenchymal tumors in transgenic mice.
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   Abstract »    PDF »
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   Abstract »    PDF »
Trans-activator gene of human T-lymphotropic virus type III (HTLV-III).
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   Abstract »    PDF »
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   Abstract »    PDF »
HTLV x-gene product: requirement for the env methionine initiation codon.
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   Abstract »    PDF »
Studies of the putative transforming protein of the type I human T-cell leukemia virus.
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   Abstract »    PDF »
Deregulation of interleukin-2 receptor gene expression in HTLV-I-induced adult T-cell leukemia.
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Science 227, 1227-1228
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G. B. Scott, M. A. Fischl, N. Klimas, M. A. Fletcher, G. M. Dickinson, R. S. Levine, and W. P. Parks (1985)
JAMA 253, 363-366
   Abstract »    PDF »
Diagnostic potential for human malignancies of bacterially produced HTLV-I envelope protein.
K. Samuel, J. Lautenberger, C. Jorcyk, S Josephs, F Wong-Staal, and T. Papas (1984)
Science 226, 1094-1097
   Abstract »    PDF »
Alteration of T-cell functions by infection with HTLV-I or HTLV-II.
M Popovic, N Flomenberg, D. Volkman, D Mann, A. Fauci, B Dupont, and R. Gallo (1984)
Science 226, 459-462
   Abstract »    PDF »
Expression of the 3' terminal region of human T-cell leukemia viruses.
W Wachsman, K Shimotohno, S. Clark, D. Golde, and I. Chen (1984)
Science 226, 177-179
   Abstract »    PDF »
Antigens encoded by the 3'-terminal region of human T-cell leukemia virus: evidence for a functional gene.
T. Lee, J. Coligan, J. Sodroski, W. Haseltine, S. Salahuddin, F Wong-Staal, R. Gallo, and M Essex (1984)
Science 226, 57-61
   Abstract »    PDF »
Identification of the putative transforming protein of the human T-cell leukemia viruses HTLV-I and HTLV-II.
D. Slamon, K Shimotohno, M. Cline, D. Golde, and I. Chen (1984)
Science 226, 61-65
   Abstract »    PDF »
Human T-cell leukemia virus (HTLV-I) antibodies in Africa.
W Saxinger, W. Blattner, P. Levine, J Clark, R Biggar, M Hoh, J Moghissi, P Jacobs, L Wilson, R Jacobson, et al. (1984)
Science 225, 1473-1476
   Abstract »    PDF »
Functional properties of antigen-specific T cells infected by human T-cell leukemia-lymphoma virus (HTLV-I).
H Mitsuya, H. Guo, J Cossman, M Megson, M. Reitz Jr, and S Broder (1984)
Science 225, 1484-1486
   Abstract »    PDF »
Lymphoma in macaques: association with virus of human T lymphotrophic family.
T Homma, P. Kanki, N. King Jr, R. Hunt, M. O'Connell, N. Letvin, M. Daniel, R. Desrosiers, C. Yang, and M Essex (1984)
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   Abstract »    PDF »
Selective tropism of lymphadenopathy associated virus (LAV) for helper-inducer T lymphocytes.
D Klatzmann, F Barre-Sinoussi, M. Nugeyre, C Danquet, E Vilmer, C Griscelli, F Brun-Veziret, C Rouzioux, J. Gluckman, J. Chermann, et al. (1984)
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Antigens on HTLV-infected cells recognized by leukemia and AIDS sera are related to HTLV viral glycoprotein.
J Schupbach, M. Sarngadharan, and R. Gallo (1984)
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Detection, isolation, and continuous production of cytopathic retroviruses (HTLV-III) from patients with AIDS and pre-AIDS.
M Popovic, M. Sarngadharan, E Read, and R. Gallo (1984)
Science 224, 497-500
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Serological analysis of a subgroup of human T-lymphotropic retroviruses (HTLV-III) associated with AIDS.
J Schupbach, M Popovic, R. Gilden, M. Gonda, M. Sarngadharan, and R. Gallo (1984)
Science 224, 503-505
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T-Cell Lymphoproliferative Syndrome Associated with Human T-Cell Leukemia/Lymphoma Virus.
S. BRODER, P. A. BUNN Jr., E. S. JAFFE, W. BLATTNER, R. C. GALLO, F. WONG-STAAL, T. A. WALDMANN, and V. T. DeVITA Jr. (1984)
Ann Intern Med 100, 543-557
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Transformation and cytopathogenic effect in an immune human T-cell clone infected by HTLV-I.
H Mitsuya, H. Guo, M Megson, C Trainor, M. Reitz Jr, and S Broder (1984)
Science 223, 1293-1296
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Novel viral sequences related to human T-cell leukemia virus in T cells of a seropositive baboon.
H. Guo, F Wong-Stall, and R. Gallo (1984)
Science 223, 1195-1197
   Abstract »    PDF »
T-cell growth factor gene: lack of expression in human T-cell leukemia-lymphoma virus-infected cells.
S. Arya, F Wong-Staal, and R. Gallo (1984)
Science 223, 1086-1087
   Abstract »    PDF »
Lymphokine production by cultured human T cells transformed by human T-cell leukemia-lymphoma virus-I.
S. Salahuddin, P. Markham, S. Lindner, J Gootenberg, M Popovic, H Hemmi, P. Sarin, and R. Gallo (1984)
Science 223, 703-707
   Abstract »    PDF »
Gene for T-cell growth factor: location on human chromosome 4q and feline chromosome B1.
L. Seigel, M. Harper, F Wong-Staal, R. Gallo, W. Nash, and S. O'Brien (1984)
Science 223, 175-178
   Abstract »    PDF »
Acquired Immunodeficiency Syndrome: Epidemiologic, Clinical, Immunologic, and Therapeutic Considerations.
A. S. FAUCI, A. M. MACHER, D. L. LONGO, H. C. LANE, A. H. ROOK, H. MASUR, and E. P. GELMANN (1984)
Ann Intern Med 100, 92-106
   Abstract »    PDF »
Productive infection and cell-free transmission of human T-cell leukemia virus in a nonlymphoid cell line.
P Clapham, K Nagy, R Cheingsong-Popov, M Exley, and R. Weiss (1983)
Science 222, 1125-1127
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The Human T-Cell Leukemia-Lymphoma Virus in the Southeastern United States.
D. W. Blayney, W. A. Blattner, M. Robert-Guroff, E. S. Jaffe, R. I. Fisher, P. A. Bunn Jr, M. G. Patton, H. R. Rarick, and R. C. Gallo (1983)
JAMA 250, 1048-1052
   Abstract »    PDF »
Human T-Cell Leukemia-Lymphoma Virus and Adult T-Cell Leukemia.
W. A. Blattner, K. Takatsuki, and R. C. Gallo (1983)
JAMA 250, 1074-1080
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Antibodies to cell membrane antigens associated with human T-cell leukemia virus in patients with AIDS.
M Essex, M. McLane, T. Lee, L Falk, C. Howe, J. Mullins, C Cabradilla, and D. Francis (1983)
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Proviral DNA of a retrovirus, human T-cell leukemia virus, in two patients with AIDS.
E. Gelmann, M Popovic, D Blayney, H Masur, G Sidhu, R. Stahl, and R. Gallo (1983)
Science 220, 862-865
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Isolation of human T-cell leukemia virus in acquired immune deficiency syndrome (AIDS).
R. Gallo, P. Sarin, E. Gelmann, M Robert-Guroff, E Richardson, V. Kalyanaraman, D Mann, G. Sidhu, R. Stahl, S Zolla-Pazner, et al. (1983)
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