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Science 4 February 1983:
Vol. 219. no. 4584, pp. 503 - 505
DOI: 10.1126/science.6297002
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Articles

Science, Vol 219, Issue 4584, 503-505
Copyright © 1983 by American Association for the Advancement of Science

articles

5' viral and human cellular sequences corresponding to the transforming gene of simian sarcoma virus

SF Josephs, R Dalla-Favera, EP Gelmann, RC Gallo, and F Wong-Staal

The 5' nucleotide sequences of the transforming gene of simian sarcoma virus (v-sis) and its human cellular homolog (c-sis) were compared. A short homology was found between helper virus and cellular DNA sequences at the junction of v-sis and c-sis, which may have had a role in the original recombination event leading to the generation of simian sarcoma virus.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Transforming potential of human c-sis nucleotide sequences encoding platelet-derived growth factor.
S. Josephs, L Ratner, M. Clarke, E. Westin, M. Reitz, and F Wong-Staal (1984)
Science 225, 636-639
   Abstract »    PDF »
Human-proto-oncogene nucleotide sequences corresponding to the transforming region of simian sarcoma virus.
S. Josephs, C Guo, L Ratner, and F Wong-Staal (1984)
Science 223, 487-491
   Abstract »    PDF »
Gene product of v-fgr onc: hybrid protein containing a portion of actin and a tyrosine-specific protein kinase.
G Naharro, K. Robbins, and E. Reddy (1984)
Science 223, 63-66
   Abstract »    PDF »


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