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Science 26 November 1982:
Vol. 218. no. 4575, pp. 891 - 894
DOI: 10.1126/science.6813968
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Articles

Science, Vol 218, Issue 4575, 891-894
Copyright © 1982 by American Association for the Advancement of Science

articles

Neuromagnetic localization of epileptiform spike activity in the human brain

DS Barth, W Sutherling, J Engel Jr, and J Beatty

Local paroxysmal discharges of epileptic tissue within the human brain, which may be electrically recorded as voltage spikes in the electroencephalogram, also generate extracranial magnetic fields. These fields were assessed by means of recently developed neuromagnetometric techniques. Surface measurements of magnetic spike field strength in the region of the focus appear sufficient to establish the location, depth, orientation, and polarity of currents underlying the paroxysmal discharge.


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