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Science 12 November 1982:
Vol. 218. no. 4573, pp. 693 - 695
DOI: 10.1126/science.6291151
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Articles

Science, Vol 218, Issue 4573, 693-695
Copyright © 1982 by American Association for the Advancement of Science

articles

Cotransmitters in the motor nerves of the guinea pig vas deferens: electrophysiological evidence

P Sneddon, DP Westfall, and JS Fedan

The contractile response of the guinea pig vas deferens to motor nerve stimulation is biphasic. The first phase is antagonized by the specific adenosine triphosphate-receptor antagonist arylazido aminoproprionyl adenosine triphosphate (ANAPP3), and the second by the alpha-receptor antagonist prazosin. The underlying electrical event, the excitatory junction potential, is also blocked by ANAPP3, but not by prazosin.


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Facilitation of the Purinergic Contractile Response of the Guinea Pig Vas Deferens by Sodium Orthovanadate.
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