Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.


Science 22 October 1982:
Vol. 218. no. 4570, pp. 348 - 353
DOI: 10.1126/science.6289436

Articles

Science, Vol 218, Issue 4570, 348-353
Copyright © 1982 by American Association for the Advancement of Science


articles

Genetic transformation of Drosophila with transposable element vectors

GM Rubin and AC Spradling

Exogenous DNA sequences were introduced into the Drosophila germ line. A rosy transposon (ry1), constructed by inserting a chromosomal DNA fragment containing the wild-type rosy gene into a P transposable element, transformed germ line cells in 20 to 50 percent of the injected rosy mutant embryos. Transformants contained one or two copies of chromosomally integrated, intact ry1 that were stably inherited in subsequent generations. These transformed flies had wild-type eye color indicating that the visible genetic defect in the host strain could be fully and permanently corrected by the transferred gene. To demonstrate the generality of this approach, a DNA segment that does not confer a recognizable phenotype on recipients was also transferred into germ line chromosomes.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Drosophila RecQ4 Has a 3'-5' DNA Helicase Activity That Is Essential for Viability.
C. Capp, J. Wu, and T.-s. Hsieh (2009)
J. Biol. Chem. 284, 30845-30852
   Abstract »    Full Text »    PDF »
Phenotypic inheritance induced by hairpin RNA in Drosophila.
H. Li and Y. Lu (2009)
Acta Biochim Biophys Sin 41, 922-928
   Abstract »    Full Text »    PDF »
In Vivo Role of a Potassium Channel-Binding Protein in Regulating Neuronal Excitability and Behavior.
M. Shahidullah, S. Reddy, H. Fei, and I. B. Levitan (2009)
J. Neurosci. 29, 13328-13337
   Abstract »    Full Text »    PDF »
Evolving enhancer-promoter interactions within the tinman complex of the flour beetle, Tribolium castaneum.
J. D. Cande, V. S. Chopra, and M. Levine (2009)
Development 136, 3153-3160
   Abstract »    Full Text »    PDF »
A chromatin insulator mediates transgene homing and very long-range enhancer-promoter communication.
M. Fujioka, X. Wu, and J. B. Jaynes (2009)
Development 136, 3077-3087
   Abstract »    Full Text »    PDF »
An Isoform-Specific Mutant Reveals a Role of PDP1{varepsilon} in the Circadian Oscillator.
X. Zheng, K. Koh, M. Sowcik, C. J. Smith, D. Chen, M. N. Wu, and A. Sehgal (2009)
J. Neurosci. 29, 10920-10927
   Abstract »    Full Text »    PDF »
Essential requirement for RING finger E3 ubiquitin ligase Hakai in early embryonic development of Drosophila.
M. Kaido, H. Wada, M. Shindo, and S. Hayashi (2009)
Genes Cells 14, 1067-1077
   Abstract »    Full Text »    PDF »
Conservation of Domain Structure in a Fast-Evolving Heterochromatic SUUR Protein in Drosophilids.
A. A. Yurlova, I. V. Makunin, T. D. Kolesnikova, O. V. Posukh, E. S. Belyaeva, and I. F. Zhimulev (2009)
Genetics 183, 119-129
   Abstract »    Full Text »    PDF »
Drosophila O-GlcNAc transferase (OGT) is encoded by the Polycomb group (PcG) gene, super sex combs (sxc).
D. A. R. Sinclair, M. Syrzycka, M. S. Macauley, T. Rastgardani, I. Komljenovic, D. J. Vocadlo, H. W. Brock, and B. M. Honda (2009)
PNAS 106, 13427-13432
   Abstract »    Full Text »    PDF »
Domains of Heterochromatin Protein 1 Required for Drosophila melanogaster Heterochromatin Spreading.
K. A. Hines, D. E. Cryderman, K. M. Flannery, H. Yang, M. W. Vitalini, T. Hazelrigg, C. A. Mizzen, and L. L. Wallrath (2009)
Genetics 182, 967-977
   Abstract »    Full Text »    PDF »
Diverse transcription influences can be insulated by the Drosophila SF1 chromatin boundary.
P. Majumder, S. Roy, V. E. Belozerov, D. Bosu, M. Puppali, and H. N. Cai (2009)
Nucleic Acids Res. 37, 4227-4233
   Abstract »    Full Text »    PDF »
asunder Is a Critical Regulator of Dynein-Dynactin Localization during Drosophila Spermatogenesis.
M. A. Anderson, J. N. Jodoin, E. Lee, K. G. Hales, T. S. Hays, and L. A. Lee (2009)
Mol. Biol. Cell 20, 2709-2721
   Abstract »    Full Text »    PDF »
The Yb protein defines a novel organelle and regulates male germline stem cell self-renewal in Drosophila melanogaster.
A. Szakmary, M. Reedy, H. Qi, and H. Lin (2009)
J. Cell Biol. 185, 613-627
   Abstract »    Full Text »    PDF »
Drosophila convoluted/dALS Is an Essential Gene Required for Tracheal Tube Morphogenesis and Apical Matrix Organization.
L. E. Swanson, M. Yu, K. S. Nelson, P. Laprise, U. Tepass, and G. J. Beitel (2009)
Genetics 181, 1281-1290
   Abstract »    Full Text »    PDF »
FGF ligands in Drosophila have distinct activities required to support cell migration and differentiation.
S. Kadam, A. McMahon, P. Tzou, and A. Stathopoulos (2009)
Development 136, 739-747
   Abstract »    Full Text »    PDF »
Multiple transcription factor codes activate epidermal wound-response genes in Drosophila.
J. C. Pearson, M. T. Juarez, M. Kim, O. Drivenes, and W. McGinnis (2009)
PNAS 106, 2224-2229
   Abstract »    Full Text »    PDF »
no poles encodes a predicted E3 ubiquitin ligase required for early embryonic development of Drosophila.
J. A. Merkle, J. L. Rickmyre, A. Garg, E. B. Loggins, J. N. Jodoin, E. Lee, L. P. Wu, and L. A. Lee (2009)
Development 136, 449-459
   Abstract »    Full Text »    PDF »
The PP2C Alphabet Is a Negative Regulator of Stress-Activated Protein Kinase Signaling in Drosophila.
C. Baril, M. Sahmi, D. Ashton-Beaucage, B. Stronach, and M. Therrien (2009)
Genetics 181, 567-579
   Abstract »    Full Text »    PDF »
The Bax/Bak ortholog in Drosophila, Debcl, exerts limited control over programmed cell death.
K. A. Galindo, W.-J. Lu, J. H. Park, and J. M. Abrams (2009)
Development 136, 275-283
   Abstract »    Full Text »    PDF »
A Drosophila Protein Family Implicated in Pheromone Perception Is Related to Tay-Sachs GM2-Activator Protein.
E. Starostina, A. Xu, H. Lin, and C. W. Pikielny (2009)
J. Biol. Chem. 284, 585-594
   Abstract »    Full Text »    PDF »
The actin-binding protein Lasp promotes Oskar accumulation at the posterior pole of the Drosophila embryo.
R. Suyama, A. Jenny, S. Curado, W. Pellis-van Berkel, and A. Ephrussi (2009)
Development 136, 95-105
   Abstract »    Full Text »    PDF »
Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases.
K. J. Beumer, J. K. Trautman, A. Bozas, J.-L. Liu, J. Rutter, J. G. Gall, and D. Carroll (2008)
PNAS 105, 19821-19826
   Abstract »    Full Text »    PDF »
The DNA-binding Polycomb-group protein Pleiohomeotic maintains both active and repressed transcriptional states through a single site.
M. Fujioka, G. L. Yusibova, J. Zhou, and J. B. Jaynes (2008)
Development 135, 4131-4139
   Abstract »    Full Text »    PDF »
A Mucin-type O-Glycosyltransferase Modulates Cell Adhesion during Drosophila Development.
L. Zhang, Y. Zhang, and K. G. T. Hagen (2008)
J. Biol. Chem. 283, 34076-34086
   Abstract »    Full Text »    PDF »
Establishment of Tribolium as a Genetic Model System and Its Early Contributions to Evo-Devo.
R. Denell (2008)
Genetics 180, 1779-1786
   Full Text »    PDF »
Telomere Loss Provokes Multiple Pathways to Apoptosis and Produces Genomic Instability in Drosophila melanogaster.
S. W. A. Titen and K. G. Golic (2008)
Genetics 180, 1821-1832
   Abstract »    Full Text »    PDF »
Drosophila Maternal Hsp83 mRNA Destabilization Is Directed by Multiple SMAUG Recognition Elements in the Open Reading Frame.
J. L. Semotok, H. Luo, R. L. Cooperstock, A. Karaiskakis, H. K. Vari, C. A. Smibert, and H. D. Lipshitz (2008)
Mol. Cell. Biol. 28, 6757-6772
   Abstract »    Full Text »    PDF »
Drosophila MFAP1 Is Required for Pre-mRNA Processing and G2/M Progression.
D. S. Andersen and N. Tapon (2008)
J. Biol. Chem. 283, 31256-31267
   Abstract »    Full Text »    PDF »
Recombineering-mediated tagging of Drosophila genomic constructs for in vivo localization and acute protein inactivation.
K. J. T. Venken, J. Kasprowicz, S. Kuenen, J. Yan, B. A. Hassan, and P. Verstreken (2008)
Nucleic Acids Res. 36, e114
   Abstract »    Full Text »    PDF »
Anillin-mediated Targeting of Peanut to Pseudocleavage Furrows Is Regulated by the GTPase Ran.
R. V. Silverman-Gavrila, K. G. Hales, and A. Wilde (2008)
Mol. Biol. Cell 19, 3735-3744
   Abstract »    Full Text »    PDF »
From the Cover: The Drosophila cohesin subunit Rad21 is a trithorax group (trxG) protein.
G. Hallson, M. Syrzycka, S. A. Beck, J. A. Kennison, D. Dorsett, S. L. Page, S. M. Hunter, R. Keall, W. D. Warren, H. W. Brock, et al. (2008)
PNAS 105, 12405-12410
   Abstract »    Full Text »    PDF »
The expanding role of mouse genetics for understanding human biology and disease.
D. Nguyen and T. Xu (2008)
Dis. Model. Mech. 1, 56-66
   Abstract »    Full Text »    PDF »
Mitochondrial Transcription Factor B2 Is Essential for Metabolic Function in Drosophila melanogaster Development.
C. Adan, Y. Matsushima, R. Hernandez-Sierra, R. Marco-Ferreres, M. A. Fernandez-Moreno, E. Gonzalez-Vioque, M. Calleja, J. J. Aragon, L. S. Kaguni, and R. Garesse (2008)
J. Biol. Chem. 283, 12333-12342
   Abstract »    Full Text »    PDF »
Mutations in String/CDC25 inhibit cell cycle re-entry and neurodegeneration in a Drosophila model of Ataxia telangiectasia.
S. A. Rimkus, R. J. Katzenberger, A. T. Trinh, G. E. Dodson, R. S. Tibbetts, and D. A. Wassarman (2008)
Genes & Dev. 22, 1205-1220
   Abstract »    Full Text »    PDF »
The third RNA recognition motif of Drosophila ELAV protein has a role in multimerization.
G. Toba and K. White (2008)
Nucleic Acids Res. 36, 1390-1399
   Abstract »    Full Text »    PDF »
Myocyte Enhancer Factor 2 and Chorion Factor 2 Collaborate in Activation of the Myogenic Program in Drosophila.
K. K. K. Tanaka, A. L. Bryantsev, and R. M. Cripps (2008)
Mol. Cell. Biol. 28, 1616-1629
   Abstract »    Full Text »    PDF »
Targeted Gene Deletion and Phenotypic Analysis of the Drosophila melanogaster Seminal Fluid Protease Inhibitor Acp62F.
J. L. Mueller, J. R. Linklater, K. Ravi Ram, T. Chapman, and M. F. Wolfner (2008)
Genetics 178, 1605-1614
   Abstract »    Full Text »    PDF »
Visual pattern memory requires foraging function in the central complex of Drosophila.
Z. Wang, Y. Pan, W. Li, H. Jiang, L. Chatzimanolis, J. Chang, Z. Gong, and L. Liu (2008)
Learn. Mem. 15, 133-142
   Abstract »    Full Text »    PDF »
Red flag on the white reporter: a versatile insulator abuts the white gene in Drosophila and is omnipresent in mini-white constructs.
D. Chetverina, E. Savitskaya, O. Maksimenko, L. Melnikova, O. Zaytseva, A. Parshikov, A. V. Galkin, and P. Georgiev (2008)
Nucleic Acids Res. 36, 929-937
   Abstract »    Full Text »    PDF »
Identification of Motifs That Are Conserved in 12 Drosophila Species and Regulate Midline Glia vs. Neuron Expression.
P. Estes, E. Fulkerson, and Y. Zhang (2008)
Genetics 178, 787-799
   Abstract »    Full Text »    PDF »
A stem-loop structure in the wingless transcript defines a consensus motif for apical RNA transport.
G. dos Santos, A. J. Simmonds, and H. M. Krause (2008)
Development 135, 133-143
   Abstract »    Full Text »    PDF »
collier transcription in a single Drosophila muscle lineage: the combinatorial control of muscle identity.
L. Dubois, J. Enriquez, V. Daburon, F. Crozet, G. Lebreton, M. Crozatier, and A. Vincent (2007)
Development 134, 4347-4355
   Abstract »    Full Text »    PDF »
Nucleocytoplasmic shuttling mediates the dynamic maintenance of nuclear Dorsal levels during Drosophila embryogenesis.
R. DeLotto, Y. DeLotto, R. Steward, and J. Lippincott-Schwartz (2007)
Development 134, 4233-4241
   Abstract »    Full Text »    PDF »
Isolation and characterization of the Drosophila ubiquilin ortholog dUbqln: in vivo interaction with early-onset Alzheimer disease genes.
A. Li, Z. Xie, Y. Dong, K. M. McKay, M. L. McKee, and R. E. Tanzi (2007)
Hum. Mol. Genet. 16, 2626-2639
   Abstract »    Full Text »    PDF »
Transgenesis upgrades for Drosophila melanogaster.
K. J. T. Venken and H. J. Bellen (2007)
Development 134, 3571-3584
   Abstract »    Full Text »    PDF »
New Properties of Drosophila Fab-7 Insulator.
S. Rodin, O. Kyrchanova, E. Pomerantseva, A. Parshikov, and P. Georgiev (2007)
Genetics 177, 113-121
   Abstract »    Full Text »    PDF »
Homeostatic Mechanisms for Iron Storage Revealed by Genetic Manipulations and Live Imaging of Drosophila Ferritin.
F. Missirlis, S. Kosmidis, T. Brody, M. Mavrakis, S. Holmberg, W. F. Odenwald, E. M. C. Skoulakis, and T. A. Rouault (2007)
Genetics 177, 89-100
   Abstract »    Full Text »    PDF »
Bedraggled, a Putative Transporter, Influences the Tissue Polarity Complex During the R3/R4 Fate Decision in the Drosophila Eye.
A. S. Rawls, S. A. Schultz, R. D. Mitra, and T. Wolff (2007)
Genetics 177, 313-328
   Abstract »    Full Text »    PDF »
Rhythm Defects Caused by Newly Engineered Null Mutations in Drosophila's cryptochrome Gene.
E. Dolezelova, D. Dolezel, and J. C. Hall (2007)
Genetics 177, 329-345
   Abstract »    Full Text »    PDF »
The AKAP Yu is required for olfactory long-term memory formation in Drosophila.
Y. Lu, Y.-S. Lu, Y. Shuai, C. Feng, T. Tully, Z. Xie, Y. Zhong, and H.-M. Zhou (2007)
PNAS 104, 13792-13797
   Abstract »    Full Text »    PDF »
Cotranscriptional recruitment of the dosage compensation complex to X-linked target genes.
J. Kind and A. Akhtar (2007)
Genes & Dev. 21, 2030-2040
   Abstract »    Full Text »    PDF »
A Double-Bromodomain Protein, FSH-S, Activates the Homeotic Gene Ultrabithorax through a Critical Promoter-Proximal Region.
Y.-L. Chang, B. King, S.-C. Lin, J. A. Kennison, and D.-H. Huang (2007)
Mol. Cell. Biol. 27, 5486-5498
   Abstract »    Full Text »    PDF »
Translational control of meiotic cell cycle progression and spermatid differentiation in male germ cells by a novel eIF4G homolog.
C. C. Baker and M. T. Fuller (2007)
Development 134, 2863-2869
   Abstract »    Full Text »    PDF »
Epigenetic regulation of the Drosophila chromosome 4 by the histone H3K9 methyltransferase dSETDB1.
T.-Y. Tzeng, C.-H. Lee, L.-W. Chan, and C.-K. J. Shen (2007)
PNAS 104, 12691-12696
   Abstract »    Full Text »    PDF »
Divergent functions and distinct localization of the Notch ligands DLL1 and DLL3 in vivo.
I. Geffers, K. Serth, G. Chapman, R. Jaekel, K. Schuster-Gossler, R. Cordes, D. B. Sparrow, E. Kremmer, S. L. Dunwoodie, T. Klein, et al. (2007)
J. Cell Biol. 178, 465-476
   Abstract »    Full Text »    PDF »
Two distinct but convergent groups of cells trigger Torso receptor tyrosine kinase activation by independently expressing torso-like.
M. Furriols, G. Ventura, and J. Casanova (2007)
PNAS 104, 11660-11665
   Abstract »    Full Text »    PDF »
Evolution of the dorsal-ventral patterning network in the mosquito, Anopheles gambiae.
Y. Goltsev, N. Fuse, M. Frasch, R. P. Zinzen, G. Lanzaro, and M. Levine (2007)
Development 134, 2415-2424
   Abstract »    Full Text »    PDF »
CTCF-Dependent Chromatin Boundary Element between the Latency-Associated Transcript and ICP0 Promoters in the Herpes Simplex Virus Type 1 Genome.
Q. Chen, L. Lin, S. Smith, J. Huang, S. L. Berger, and J. Zhou (2007)
J. Virol. 81, 5192-5201
   Abstract »    Full Text »    PDF »
Control of Sigma Virus Multiplication by the ref(2)P Gene of Drosophila melanogaster: An in Vivo Study of the PB1 Domain of Ref(2)P.
A. Carre-Mlouka, S. Gaumer, P. Gay, A. M. Petitjean, C. Coulondre, P. Dru, F. Bras, S. Dezelee, and D. Contamine (2007)
Genetics 176, 409-419
   Abstract »    Full Text »    PDF »
tailup, a LIM-HD gene, and Iro-C cooperate in Drosophila dorsal mesothorax specification.
J. de Navascues and J. Modolell (2007)
Development 134, 1779-1788
   Abstract »    Full Text »    PDF »
Receptor-Like Tyrosine Phosphatase PTP10D Is Required for Long-Term Memory in Drosophila.
M. Qian, G. Pan, L. Sun, C. Feng, Z. Xie, T. Tully, and Y. Zhong (2007)
J. Neurosci. 27, 4396-4402
   Abstract »    Full Text »    PDF »
Thioredoxin Suppresses Parkin-associated Endothelin Receptor-like Receptor-induced Neurotoxicity and Extends Longevity in Drosophila.
Y. Umeda-Kameyama, M. Tsuda, C. Ohkura, T. Matsuo, Y. Namba, Y. Ohuchi, and T. Aigaki (2007)
J. Biol. Chem. 282, 11180-11187
   Abstract »    Full Text »    PDF »
Idefix insulator activity can be modulated by nearby regulatory elements.
E. Brasset, F. Bantignies, F. Court, S. Cheresiz, C. Conte, and C. Vaury (2007)
Nucleic Acids Res.
   Abstract »    Full Text »    PDF »
A role for a novel centrosome cycle in asymmetric cell division.
N. M. Rusan and M. Peifer (2007)
J. Cell Biol. 177, 13-20
   Abstract »    Full Text »    PDF »
In Vivo Construction of Transgenes in Drosophila.
H. Takeuchi, O. Georgiev, M. Fetchko, M. Kappeler, W. Schaffner, and D. Egli (2007)
Genetics 175, 2019-2028
   Abstract »    Full Text »    PDF »
Stereotypic founder cell patterning and embryonic muscle formation in Drosophila require nautilus (MyoD) gene function.
Q. Wei, Y. Rong, and B. M. Paterson (2007)
PNAS 104, 5461-5466
   Abstract »    Full Text »    PDF »
Exploring Strategies for Protein Trapping in Drosophila.
A. T. Quinones-Coello, L. N. Petrella, K. Ayers, A. Melillo, S. Mazzalupo, A. M. Hudson, S. Wang, C. Castiblanco, M. Buszczak, R. A. Hoskins, et al. (2007)
Genetics 175, 1089-1104
   Abstract »    Full Text »    PDF »
Cis-Regulatory Elements in the Accord Retrotransposon Result in Tissue-Specific Expression of the Drosophila melanogaster Insecticide Resistance Gene Cyp6g1.
H. Chung, M. R. Bogwitz, C. McCart, A. Andrianopoulos, R. H. ffrench-Constant, P. Batterham, and P. J. Daborn (2007)
Genetics 175, 1071-1077
   Abstract »    Full Text »    PDF »
Promoter targeting sequence mediates enhancer interference in the Drosophila embryo.
Q. Lin, Q. Chen, L. Lin, S. Smith, and J. Zhou (2007)
PNAS 104, 3237-3242
   Abstract »    Full Text »    PDF »
An optimized transgenesis system for Drosophila using germ-line-specific {varphi}C31 integrases.
J. Bischof, R. K. Maeda, M. Hediger, F. Karch, and K. Basler (2007)
PNAS 104, 3312-3317
   Abstract »    Full Text »    PDF »
A Novel Repeat-Associated Small Interfering RNA-Mediated Silencing Pathway Downregulates Complementary Sense gypsy Transcripts in Somatic Cells of the Drosophila Ovary.
A. Pelisson, E. Sarot, G. Payen-Groschene, and A. Bucheton (2007)
J. Virol. 81, 1951-1960
   Abstract »    Full Text »    PDF »
Causative role of oxidative stress in a Drosophila model of Friedreich ataxia.
J. V. Llorens, J. A. Navarro, M. J. Martinez-Sebastian, M. K. Baylies, S. Schneuwly, J. A. Botella, and M. D. Molto (2007)
FASEB J 21, 333-344
   Abstract »    Full Text »    PDF »
Antagonizing Scalloped With a Novel Vestigial Construct Reveals an Important Role for Scalloped in Drosophila melanogaster Leg, Eye and Optic Lobe Development.
A. Garg, A. Srivastava, M. M. Davis, S. L. O'Keefe, L. Chow, and J. B. Bell (2007)
Genetics 175, 659-669
   Abstract »    Full Text »    PDF »
An Ectopic Expression Screen Reveals the Protective and Toxic Effects of Drosophila Seminal Fluid Proteins.
J. L. Mueller, J. L. Page, and M. F. Wolfner (2007)
Genetics 175, 777-783
   Abstract »    Full Text »    PDF »
A Drosophila Model of Mutant Human Parkin-Induced Toxicity Demonstrates Selective Loss of Dopaminergic Neurons and Dependence on Cellular Dopamine.
T.-K. Sang, H.-Y. Chang, G. M. Lawless, A. Ratnaparkhi, L. Mee, L. C. Ackerson, N. T. Maidment, D. E. Krantz, and G. R. Jackson (2007)
J. Neurosci. 27, 981-992
   Abstract »    Full Text »    PDF »
A UDP-GalNAc:Polypeptide N-Acetylgalactosaminyltransferase Is Required for Epithelial Tube Formation.
E Tian and K. G. T. Hagen (2007)
J. Biol. Chem. 282, 606-614
   Abstract »    Full Text »    PDF »
P[acman]: A BAC Transgenic Platform for Targeted Insertion of Large DNA Fragments in D. melanogaster.
K. J. T. Venken, Y. He, R. A. Hoskins, and H. J. Bellen (2006)
Science 314, 1747-1751
   Abstract »    Full Text »    PDF »
Direct control of neurogenesis by selector factors in the fly eye: regulation of atonal by Ey and So.
T. Zhang, S. Ranade, C. Q. Cai, C. Clouser, and F. Pignoni (2006)
Development 133, 4881-4889
   Abstract »    Full Text »    PDF »
Predicted seminal astacin-like protease is required for processing of reproductive proteins in Drosophila melanogaster.
K. Ravi Ram, L. K. Sirot, and M. F. Wolfner (2006)
PNAS 103, 18674-18679
   Abstract »    Full Text »    PDF »
Accelerated Accumulation of Misfolded Prion Protein and Spongiform Degeneration in a Drosophila Model of Gerstmann-Straussler-Scheinker Syndrome.
B. A. Gavin, M. J. Dolph, N. R. Deleault, J. C. Geoghegan, V. Khurana, M. B. Feany, P. J. Dolph, and S. Supattapone (2006)
J. Neurosci. 26, 12408-12414
   Abstract »    Full Text »    PDF »
The Drosophila radish gene encodes a protein required for anesthesia-resistant memory.
E. Folkers, S. Waddell, and W. G. Quinn (2006)
PNAS 103, 17496-17500
   Abstract »    Full Text »    PDF »
Two Isoforms of Drosophila TRF2 Are Involved in Embryonic Development, Premeiotic Chromatin Condensation, and Proper Differentiation of Germ Cells of Both Sexes..
D. V. Kopytova, A. N. Krasnov, M. R. Kopantceva, E. N. Nabirochkina, J. V. Nikolenko, O. Maksimenko, M. M. Kurshakova, L. A. Lebedeva, M. M. Yerokhin, O. B. Simonova, et al. (2006)
Mol. Cell. Biol. 26, 7492-7505
   Abstract »    Full Text »    PDF »
A Drosophila model of the rhabdomyosarcoma initiator PAX7-FKHR.
R. L. Galindo, J. A. Allport, and E. N. Olson (2006)
PNAS 103, 13439-13444
   Abstract »    Full Text »    PDF »
Behavioral Responses to Odorants in Drosophila Require Nervous System Expression of the {beta} Integrin Gene Myospheroid.
P. Bhandari, J. W. Gargano, M. M. Goddeeris, and M. S. Grotewiel (2006)
Chem Senses 31, 627-639
   Abstract »    Full Text »    PDF »
Drosophila Reptin and Other TIP60 Complex Components Promote Generation of Silent Chromatin.
D. Qi, H. Jin, T. Lilja, and M. Mannervik (2006)
Genetics 174, 241-251
   Abstract »    Full Text »    PDF »
Of Two Cytosolic Aconitases Expressed in Drosophila, Only One Functions as an Iron-regulatory Protein.
M. I. Lind, F. Missirlis, O. Melefors, H. Uhrigshardt, K. Kirby, J. P. Phillips, K. Soderhall, and T. A. Rouault (2006)
J. Biol. Chem. 281, 18707-18714
   Abstract »    Full Text »    PDF »
Characterization of Drosophila mini-me, a Gene Required for Cell Proliferation and Survival.
C. Jones, R. Reifegerste, and K. Moses (2006)
Genetics 173, 793-808
   Abstract »    Full Text »    PDF »
Site-Specific Transformation of Drosophila via {phi}C31 Integrase-Mediated Cassette Exchange.
J. R. Bateman, A. M. Lee, and C.-t. Wu (2006)
Genetics 173, 769-777
   Abstract »    Full Text »    PDF »
Programmed cell death mechanisms of identifiable peptidergic neurons in Drosophila melanogaster.
Y.-J. Choi, G. Lee, and J. H. Park (2006)
Development 133, 2223-2232
   Abstract »    Full Text »    PDF »
Drosophila melanogaster auxilin regulates the internalization of Delta to control activity of the Notch signaling pathway.
E. J. Hagedorn, J. L. Bayraktar, V. R. Kandachar, T. Bai, D. M. Englert, and H. C. Chang (2006)
J. Cell Biol. 173, 443-452
   Abstract »    Full Text »    PDF »
Molecular Genetics of Natural Populations.
A. J. Greenberg and C.-I Wu (2006)
Mol. Biol. Evol. 23, 883-886
   Abstract »    Full Text »    PDF »
The Mcp Element Mediates Stable Long-Range Chromosome-Chromosome Interactions in Drosophila.
J. Vazquez, M. Muller, V. Pirrotta, and J. W. Sedat (2006)
Mol. Biol. Cell 17, 2158-2165
   Abstract »    Full Text »    PDF »



To Advertise     Find Products


Science. ISSN 0036-8075 (print), 1095-9203 (online)