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Science 8 October 1982:
Vol. 218. no. 4568, pp. 173 - 175
DOI: 10.1126/science.7123228
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Articles

Science, Vol 218, Issue 4568, 173-175
Copyright © 1982 by American Association for the Advancement of Science

articles

Serial position curve in rats: role of the dorsal hippocampus

RP Kesner and JM Novak

In an eight-arm radial maze, normal rats demonstrated good immediate retention for the order of first items (primacy component of serial position curve) and last items (recency component of serial position curve) of an eight-item (arm) list. In contrast, rats with dorsal hippocampal lesions displayed, on an immediate retention test, disruption of the primacy but not the recency component of the serial position curve. Furthermore, imposing a 10-minute delay before the retention test impaired all components of the serial position curve. These results support correspondence in mnemonic function of the hippocampus in animals and humans.


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