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Science 10 September 1982: Vol. 217. no. 4564, pp. 1050 - 1053 DOI: 10.1126/science.7051286
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Articles
Science, Vol 217, Issue 4564, 1050-1053
Copyright © 1982 by American Association for the Advancement of Science
Myocardial injury: quantitation by cell sorting initiated with antimyosin fluorescent spheres
BA Khaw,
J Scott,
JT Fallon,
SL Cahill,
E Haber,
and
C Homcy
Spheres coated with antibodies specific for myosin were used to detect myocardial cell membrane disruption by scanning electron microscopy. Injury in a population of cultured myocytes as then followed and measured by fluorescence-activated cell sorting. This approach provides a unique method for quantitating the evolution of myocardial injury and potentially for assessing the efficacy of interventions aimed at myocardial protection.
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