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Science 13 August 1982:
Vol. 217. no. 4560, pp. 647 - 648
DOI: 10.1126/science.217.4560.647
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Articles

Natural and Synthetic Allatotoxins: Suicide Substrates for Juvenile Hormone Biosynthesis

W. S. BOWERS 1, P. H. EVANS 1, P. A. MARSELLA 1, D. M. SODERLUND 1, and F. BETTARINI 2

1 New York State Agricultural Experiment Station, Cornell University, Geneva 14456
2 Montedison, Instituto Ricerche Donegani, Novara, Italy

Cytotoxic agents with antijuvenile hormone activity in insects have been discovered. Their mechanism of action may involve an oxidative bioactivation into a reactive quinone methide.

Submitted on June 4, 1982

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Science. ISSN 0036-8075 (print), 1095-9203 (online)