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Science 9 July 1982:
Vol. 217. no. 4555, pp. 155 - 157
DOI: 10.1126/science.217.4555.155
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Articles

Localization of a Circadian Pacemaker in the Eye of a Mollusc, Bulla

GENE D. BLOCK 1 and STEVEN F. WALLACE 1

1 Department of Biology, University of Virginia, Charlottesville 22901

The eye of the marine mollusc Bulla contains a circadian pacemaker which, along with critical entrainment pathways, is located among a small group of neurons at the base of the retina. Long-term intracellular recording from cells of the organized photoreceptor layer, which constitutes most of the retinal volume, indicates that these cells are not involved in generating the rhythm since rhythmic changes in membrane potential were not observed. In addition, surgical removal of the entire photoreceptor layer does not alter the period of the circadian rhythm and does not prevent phase shifts by light pulses.

Submitted on November 19, 1981
Revised on May 10, 1982


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
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Mutual coupling between the ocular circadian pacemakers of Bulla gouldiana.
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