Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 2 July 1982:
Vol. 217. no. 4554, pp. 67 - 68
DOI: 10.1126/science.7089542
Prev | Table of Contents | Next

Articles

Science, Vol 217, Issue 4554, 67-68
Copyright © 1982 by American Association for the Advancement of Science

articles

In vitro Evidence for two distinct hippocampal growth factors: basis of neuronal plasticity?

KA Crutcher and F Collins

The rat hippocampal formation was tested for the presence of factors that would accelerate neurite extension from chick parasympathetic (ciliary ganglion) or sympathetic (lumbar chain) neurons in vitro. Two growth factors were identified in extracts of this brain region. One accelerated neurite extension from sympathetic neurons and was blocked by antiserum to nerve growth factor. The other accelerated neurite extension from parasympathetic neurons but was not affected by the antiserum. These results suggest that specific growth factors account for the specificity of neuronal sprouting.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Choline acetyltransferase activity in striatum of neonatal rats increased by nerve growth factor.
W. Mobley, J. Rutkowski, G. Tennekoon, K Buchanan, and M. Johnston (1985)
Science 229, 284-287
   Abstract »    PDF »
Promoting functional plasticity in the damaged nervous system.
W. Freed, L de Medinaceli, and R. Wyatt (1985)
Science 227, 1544-1552
   Abstract »    PDF »
Cell biology of synaptic plasticity.
C. Cotman and M Nieto-Sampedro (1984)
Science 225, 1287-1294
   Abstract »    PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)