Science, Vol 217, Issue 4554, 59-61
Copyright © 1982 by American Association for the Advancement of Science
Differential breakdown of phylogenetically diverse ribosomal RNA's inserted via liposomes into mammalian cells
D Lavelle,
MJ Ostro,
and
D Giacomoni
Liposomes were used to deliver ribosomal RNA's from the different organisms into cultivated mouse plasmacytoma cells. Ribosomal RNA from Escherichia coli was degraded intracellularly within 1 hour, whereas mouse and yeast ribosomal RNA's were degraded more slowly. This indicates that cells can discriminated between different ribosomal RNA's.