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Science 28 May 1982:
Vol. 216. no. 4549, pp. 946 - 951
DOI: 10.1126/science.6281888
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Articles

Science, Vol 216, Issue 4549, 946-951
Copyright © 1982 by American Association for the Advancement of Science

articles

Suppression of transcription termination by phage lambda

DF Ward and ME Gottesman

The bacteriophage lambda N gene product positively controls development by preventing termination of transcription at terminator sites critical to the sequential expression of phage genes. Many host transcription factors, including RNA polymerase, are involved in N gene action. Recent findings have shown that ribosomal proteins are also involved. The current understanding of how the N protein affects transcription termination is reviewed, and a possible model and current problems are discussed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Translational repression by a transcriptional elongation factor.
H. R. Wilson, L. Kameyama, J.-g. Zhou, G. Guarneros, and D. L. Court (1997)
Genes & Dev. 11, 2204-2213
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