Note to users. If you're seeing this message, it means that your browser cannot find this page's style/presentation instructions -- or possibly that you are using a browser that does not support current Web standards. Find out more about why this message is appearing, and what you can do to make your experience of our site the best it can be.

Science 16 April 1982:
Vol. 216. no. 4543, pp. 322 - 324
DOI: 10.1126/science.7063891
Prev | Table of Contents | Next

Articles

Science, Vol 216, Issue 4543, 322-324
Copyright © 1982 by American Association for the Advancement of Science

articles

Recovery of olfactory function after bilateral bulbectomy

JW Wright and JW Harding

Mice were trained to discriminate between scented and unscented air. After olfactory bulbs were removed, discrimination was lost, but returned with the formation of synaptic connections between regenerated primary olfactory neurons and the cortex of the forebrain. The acquisition of a second olfactory-mediated task by long-term bulbectomized mice and controls was indistinguishable. The results emphasize the plasticity of the nervous system, correlate the presence of neural connections between olfactory mucosa and forebrain with the recovery of olfactory function, suggest that olfactory-mediated memory resides at least in part outside the olfactory bulbs, and demonstrate that the bulbs are not required for the acquisition of olfactory tasks.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Role of Olfaction in the Conditioned Sucrose Preference of Sweet-Ageusic T1R3 Knockout Mice.
S. Zukerman, K. Touzani, R. F. Margolskee, and A. Sclafani (2009)
Chem Senses 34, 685-694
   Abstract »    Full Text »    PDF »
Olfaction in Olfactory Bulbectomized Rats.
B. Slotnick, R. Cockerham, and E. Pickett (2004)
J. Neurosci. 24, 9195-9200
   Abstract »    Full Text »    PDF »
Olfactory function after bulbectomy.
M Meredith, P. Graziadei, G. Graziadei, M. Rashotte, and J. Smith (1983)
Science 222, 1254-1255
   PDF »
Olfactory Function After Bulbectomy.
J. W. WRIGHT and J. W. HARDING (1983)
Science 222, 1255
   PDF »


To Advertise     Find Products

Science. ISSN 0036-8075 (print), 1095-9203 (online)