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Science 9 April 1982:
Vol. 216. no. 4542, pp. 191 - 193
DOI: 10.1126/science.7063879
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Articles

Science, Vol 216, Issue 4542, 191-193
Copyright © 1982 by American Association for the Advancement of Science

articles

Pregnancy suppression by active immunization against gestation-specific riboflavin carrier protein

CV Murty and PR Adiga

A riboflavin carrier protein isolated from chickens cross-reacts with a gestation-specific rodent carrier for riboflavin. Active immunization of female rats of proved fertility with the purified chicken carrier protein completely yet reversibly suppressed early pregnancy without impairing implantation per se. Concurrently there were no discernible adverse effects on maternal health in terms of weight gain, vitamin status, and fertility.




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Science. ISSN 0036-8075 (print), 1095-9203 (online)