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Science 19 March 1982:
Vol. 215. no. 4539, pp. 1516 - 1517
DOI: 10.1126/science.7063859
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Articles

Science, Vol 215, Issue 4539, 1516-1517
Copyright © 1982 by American Association for the Advancement of Science

articles

Rats self-administer nonrewarding brain stimulation to ameliorate aversion

KD Carr and EE Coons

Hypothalamic stimulation in rats both reduces escape from noxious hindbrain stimulation and sustains self-administration only when hindbrain stimulation is inescapable. Self-administration reflects an aversion-ameliorative action of brain stimulation and not a positive reinforcement process. The psychophysical testing used is offered as a model for establishing the analgesic properties of brain stimulation.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
Intrinsic mechanisms of pain inhibition: activation by stress.
G. Terman, Y Shavit, J. Lewis, J. Cannon, and J. Liebeskind (1984)
Science 226, 1270-1277
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