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Science 4 December 1981:
Vol. 214. no. 4525, pp. 1143 - 1145
DOI: 10.1126/science.7302586
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Articles

Science, Vol 214, Issue 4525, 1143-1145
Copyright © 1981 by American Association for the Advancement of Science

articles

The hagfish slime gland: a model system for studying the biology of mucus

SW Downing, WL Salo, RH Spitzer, and EA Koch

The hagfish slime gland may provide a model system for studying certain aspects of the biology of mucus. Mucus is obtained in nonhydrated form by electrically stimulating the anesthetized hagfish and the secretions are stirred into ammonium sulfate. Centrifugation and filtration are than used to isolate the two major secretory products, mucous vesicles and threads. Specific advantages of the model and potential applications for research are discussed.


THIS ARTICLE HAS BEEN CITED BY OTHER ARTICLES:
From ultra-soft slime to hard {alpha}-keratins: The many lives of intermediate filaments.
D. S. Fudge, T. Winegard, R.H. Ewoldt, D. Beriault, L. Szewciw, and G.H. McKinley (2009)
Integr. Comp. Biol. 49, 32-39
   Abstract »    Full Text »    PDF »
Hagfish slime ecomechanics: testing the gill-clogging hypothesis.
J. Lim, D. S. Fudge, N. Levy, and J. M. Gosline (2006)
J. Exp. Biol. 209, 702-710
   Abstract »    Full Text »    PDF »
Composition, morphology and mechanics of hagfish slime.
D. S. Fudge, N. Levy, S. Chiu, and J. M. Gosline (2005)
J. Exp. Biol. 208, 4613-4625
   Abstract »    Full Text »    PDF »
An unusual intermediate filament subunit from the cytoskeletal biopolymer released extracellularly into seawater by the primitive hagfish (Eptatretus stouti).
E. Koch, R. Spitzer, R. Pithawalla, and D. Parry (1994)
J. Cell Sci. 107, 3133-3144
   Abstract »    PDF »


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